Λεπτομέρειες βιβλιογραφικής εγγραφής
| Τίτλος: |
Ferroptosis as a biological phase transition IV: chronotherapy of epithelial–mesenchymal transition of the tumour growth. |
| Συγγραφείς: |
Suárez Ogando, Henry, Guerra González, Alejandro, Mansilla Corona, Ricardo, Nicado García, Miriam, Nieto Villar, José Manuel |
| Πηγή: |
Biological Rhythm Research; Oct2026, Vol. 57 Issue 10, p1053-1062, 10p |
| Θεματικοί όροι: |
Ferroptosis, Epithelial-mesenchymal transition, Drug resistance, Cancer treatment, Clinical chronobiology, Perturbation theory, Autonomous differential equations |
| Περίληψη: |
The ferroptosis process has become an alternative to overcome therapeutic resistance in various types of cancer. A non-autonomous ordinary differential equations model was developed with the aim of simulating the chrono-modulated application of a therapy based on triggering the ferroptosis process. A periodic perturbation was applied to the system in order to analyze the behaviour of cancer cells with drug resistance due to the epithelial–mesenchymal transition process. Due to this perturbation, large areas of less complexity were obtained and a reduction in mesenchymal cell populations was observed. These results contribute to a hypothesis-generating framework for investigating chrono-therapeutic modulation of treatments involving the ferroptosis process. [ABSTRACT FROM AUTHOR] |
|
Copyright of Biological Rhythm Research is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| Βάση Δεδομένων: |
Complementary Index |