Academic Journal

Portable Sensing Systems in Biological and Chemical Analyses: A Review of Sensor Technologies, Miniaturized Platforms, Data Processing, and Field Applications.

Bibliographic Details
Title: Portable Sensing Systems in Biological and Chemical Analyses: A Review of Sensor Technologies, Miniaturized Platforms, Data Processing, and Field Applications.
Authors: Chen, Hsuan-Yu, Chen, Chiachung
Source: Micromachines; Jul2026, Vol. 17 Issue 7, p863, 72p
Subject Terms: Point-of-care testing, Labs on a chip, Application software, Analytical chemistry, Detectors, Electronic data processing, Chemical research
Abstract: Portable sensing systems are increasingly important in biological and chemical analyses because they can provide analytical information at the point of decision-making. While traditional laboratory methods remain crucial for reference measurements, regulatory validation, and high-precision quantification, portable systems emphasize rapid response, convenience, cost-effectiveness, robustness, and relevance to decision-making. This paper views portable sensing systems as integrated analytical platforms rather than isolated sensing elements. The paper discusses recognition elements, including enzymes, antibodies, nucleic acid probes, aptamers, molecularly imprinted polymers, nanomaterials, and hybrid recognition interfaces, as well as electrochemical, optical, mass-sensitive, thermal, field-effect, and hybrid sensing technologies. Furthermore, this paper reviews platform designs, including paper-based analytical devices, chip lab systems, smartphone-assisted sensors, wearable and flexible sensors, handheld instruments, and wireless sensor networks. It explores their applications in sample handling, calibration, data processing, and field deployment. Applications of this technology include point-of-care diagnostics, pathogen detection, wearable health monitoring, agriculture, veterinary medicine, environmental monitoring, food safety, industrial process control, forensic analysis, public safety, and occupational exposure assessment. The report focuses on sample acquisition, miniaturized preparation, reagent storage, matrix interference, calibration transfer, signal conditioning, machine learning, cloud platforms, analytical validation, and decision support. Furthermore, it identifies key obstacles to translating academic prototypes into industrial products, including reproducibility, stability, manufacturability, ease of use, cybersecurity, regulatory approval, and market acceptance. Future development requires fully integrated sample-to-result systems, multimodal sensing, artificial intelligence, sustainable single-use materials, self-powered devices, and system-level validation under real-world operating conditions. [ABSTRACT FROM AUTHOR]
Copyright of Micromachines is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Complementary Index
FullText Text:
  Availability: 0
CustomLinks:
  – Url: https://resolver.ebsco.com/c/fiv2js/result?sid=EBSCO:edb&genre=article&issn=2072666X&ISBN=&volume=17&issue=7&date=20260701&spage=863&pages=863-934&title=Micromachines&atitle=Portable%20Sensing%20Systems%20in%20Biological%20and%20Chemical%20Analyses%3A%20A%20Review%20of%20Sensor%20Technologies%2C%20Miniaturized%20Platforms%2C%20Data%20Processing%2C%20and%20Field%20Applications.&aulast=Chen%2C%20Hsuan-Yu&id=DOI:10.3390/mi17070863
    Name: Full Text Finder (for New FTF UI) (ns324271)
    Category: fullText
    Text: Full Text Finder
    MouseOverText: Full Text Finder
Header DbId: edb
DbLabel: Complementary Index
An: 195803396
RelevancyScore: 1082
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 1082.42175292969
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Portable Sensing Systems in Biological and Chemical Analyses: A Review of Sensor Technologies, Miniaturized Platforms, Data Processing, and Field Applications.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Chen%2C+Hsuan-Yu%22">Chen, Hsuan-Yu</searchLink><br /><searchLink fieldCode="AR" term="%22Chen%2C+Chiachung%22">Chen, Chiachung</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: Micromachines; Jul2026, Vol. 17 Issue 7, p863, 72p
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Point-of-care+testing%22">Point-of-care testing</searchLink><br /><searchLink fieldCode="DE" term="%22Labs+on+a+chip%22">Labs on a chip</searchLink><br /><searchLink fieldCode="DE" term="%22Application+software%22">Application software</searchLink><br /><searchLink fieldCode="DE" term="%22Analytical+chemistry%22">Analytical chemistry</searchLink><br /><searchLink fieldCode="DE" term="%22Detectors%22">Detectors</searchLink><br /><searchLink fieldCode="DE" term="%22Electronic+data+processing%22">Electronic data processing</searchLink><br /><searchLink fieldCode="DE" term="%22Chemical+research%22">Chemical research</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Portable sensing systems are increasingly important in biological and chemical analyses because they can provide analytical information at the point of decision-making. While traditional laboratory methods remain crucial for reference measurements, regulatory validation, and high-precision quantification, portable systems emphasize rapid response, convenience, cost-effectiveness, robustness, and relevance to decision-making. This paper views portable sensing systems as integrated analytical platforms rather than isolated sensing elements. The paper discusses recognition elements, including enzymes, antibodies, nucleic acid probes, aptamers, molecularly imprinted polymers, nanomaterials, and hybrid recognition interfaces, as well as electrochemical, optical, mass-sensitive, thermal, field-effect, and hybrid sensing technologies. Furthermore, this paper reviews platform designs, including paper-based analytical devices, chip lab systems, smartphone-assisted sensors, wearable and flexible sensors, handheld instruments, and wireless sensor networks. It explores their applications in sample handling, calibration, data processing, and field deployment. Applications of this technology include point-of-care diagnostics, pathogen detection, wearable health monitoring, agriculture, veterinary medicine, environmental monitoring, food safety, industrial process control, forensic analysis, public safety, and occupational exposure assessment. The report focuses on sample acquisition, miniaturized preparation, reagent storage, matrix interference, calibration transfer, signal conditioning, machine learning, cloud platforms, analytical validation, and decision support. Furthermore, it identifies key obstacles to translating academic prototypes into industrial products, including reproducibility, stability, manufacturability, ease of use, cybersecurity, regulatory approval, and market acceptance. Future development requires fully integrated sample-to-result systems, multimodal sensing, artificial intelligence, sustainable single-use materials, self-powered devices, and system-level validation under real-world operating conditions. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label:
  Group: Ab
  Data: <i>Copyright of Micromachines is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edb&AN=195803396
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.3390/mi17070863
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 72
        StartPage: 863
    Subjects:
      – SubjectFull: Point-of-care testing
        Type: general
      – SubjectFull: Labs on a chip
        Type: general
      – SubjectFull: Application software
        Type: general
      – SubjectFull: Analytical chemistry
        Type: general
      – SubjectFull: Detectors
        Type: general
      – SubjectFull: Electronic data processing
        Type: general
      – SubjectFull: Chemical research
        Type: general
    Titles:
      – TitleFull: Portable Sensing Systems in Biological and Chemical Analyses: A Review of Sensor Technologies, Miniaturized Platforms, Data Processing, and Field Applications.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Chen, Hsuan-Yu
      – PersonEntity:
          Name:
            NameFull: Chen, Chiachung
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 07
              Text: Jul2026
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-print
              Value: 2072666X
          Numbering:
            – Type: volume
              Value: 17
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Micromachines
              Type: main
ResultId 1