Academic Journal
The Influence of Monosaccharide Composition on the Bioactivity of Medicinal Plant Polysaccharides.
| Title: | The Influence of Monosaccharide Composition on the Bioactivity of Medicinal Plant Polysaccharides. |
|---|---|
| Authors: | Fan, Xinhui, Li, Ke, Yang, Maohui, Qin, Xuemei, Li, Zhenyu, Du, Yuguang |
| Source: | International Journal of Molecular Sciences; Apr2026, Vol. 27 Issue 7, p3075, 26p |
| Subject Terms: | Monosaccharides, Polysaccharides, Immunoregulation, Antioxidants, Pharmacology, Gut microbiota, Neuroprotective agents, Antineoplastic agent development |
| Abstract: | Polysaccharides are natural polymers that are widely found in medicinal plants. Structurally, they are complex molecules composed of long chains of monosaccharide units linked by glycosidic bonds. Modern pharmacological research shows that the bioactivity of polysaccharides is closely related to their monosaccharide composition. This review summarises the monosaccharide composition of 210 polysaccharides from 72 medicinal plants. They were classified into 10 types through principal component analysis (glucans; homogalacturonan; galactans; arabinogalactans; mannans; glucomannans; arabinans; xylans; fructans; rhamnogalacturonan-I). The relationship between monosaccharide composition and biological activity was further analysed. The results are as follows: glucans make significant contributions to immunomodulation, antioxidant activity, and gut microbiota regulation; galactans are crucial for antioxidant effects, immunomodulation, and gut microbiota regulation; mannans play a key role in immunomodulation, antitumor activity, and neuroprotection; fructans are vital for gut microbiota regulation, immunomodulation, and antioxidant effects; and pectins exhibit notable immunomodulatory, antioxidant, and hypoglycaemic properties. Consequently, developing polysaccharides from medicinal plant resources based on their monosaccharide composition is expected to speed up the search for polysaccharides with high biological activity and provide a theoretical reference for polysaccharide research. [ABSTRACT FROM AUTHOR] |
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| Database: | Complementary Index |
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| Header | DbId: edb DbLabel: Complementary Index An: 192957474 RelevancyScore: 1061 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 1060.75964355469 |
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| Items | – Name: Title Label: Title Group: Ti Data: The Influence of Monosaccharide Composition on the Bioactivity of Medicinal Plant Polysaccharides. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Fan%2C+Xinhui%22">Fan, Xinhui</searchLink><br /><searchLink fieldCode="AR" term="%22Li%2C+Ke%22">Li, Ke</searchLink><br /><searchLink fieldCode="AR" term="%22Yang%2C+Maohui%22">Yang, Maohui</searchLink><br /><searchLink fieldCode="AR" term="%22Qin%2C+Xuemei%22">Qin, Xuemei</searchLink><br /><searchLink fieldCode="AR" term="%22Li%2C+Zhenyu%22">Li, Zhenyu</searchLink><br /><searchLink fieldCode="AR" term="%22Du%2C+Yuguang%22">Du, Yuguang</searchLink> – Name: TitleSource Label: Source Group: Src Data: International Journal of Molecular Sciences; Apr2026, Vol. 27 Issue 7, p3075, 26p – Name: Subject Label: Subject Terms Group: Su Data: <searchLink fieldCode="DE" term="%22Monosaccharides%22">Monosaccharides</searchLink><br /><searchLink fieldCode="DE" term="%22Polysaccharides%22">Polysaccharides</searchLink><br /><searchLink fieldCode="DE" term="%22Immunoregulation%22">Immunoregulation</searchLink><br /><searchLink fieldCode="DE" term="%22Antioxidants%22">Antioxidants</searchLink><br /><searchLink fieldCode="DE" term="%22Pharmacology%22">Pharmacology</searchLink><br /><searchLink fieldCode="DE" term="%22Gut+microbiota%22">Gut microbiota</searchLink><br /><searchLink fieldCode="DE" term="%22Neuroprotective+agents%22">Neuroprotective agents</searchLink><br /><searchLink fieldCode="DE" term="%22Antineoplastic+agent+development%22">Antineoplastic agent development</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Polysaccharides are natural polymers that are widely found in medicinal plants. Structurally, they are complex molecules composed of long chains of monosaccharide units linked by glycosidic bonds. Modern pharmacological research shows that the bioactivity of polysaccharides is closely related to their monosaccharide composition. This review summarises the monosaccharide composition of 210 polysaccharides from 72 medicinal plants. They were classified into 10 types through principal component analysis (glucans; homogalacturonan; galactans; arabinogalactans; mannans; glucomannans; arabinans; xylans; fructans; rhamnogalacturonan-I). The relationship between monosaccharide composition and biological activity was further analysed. The results are as follows: glucans make significant contributions to immunomodulation, antioxidant activity, and gut microbiota regulation; galactans are crucial for antioxidant effects, immunomodulation, and gut microbiota regulation; mannans play a key role in immunomodulation, antitumor activity, and neuroprotection; fructans are vital for gut microbiota regulation, immunomodulation, and antioxidant effects; and pectins exhibit notable immunomodulatory, antioxidant, and hypoglycaemic properties. Consequently, developing polysaccharides from medicinal plant resources based on their monosaccharide composition is expected to speed up the search for polysaccharides with high biological activity and provide a theoretical reference for polysaccharide research. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Group: Ab Data: <i>Copyright of International Journal of Molecular Sciences is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3390/ijms27073075 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 26 StartPage: 3075 Subjects: – SubjectFull: Monosaccharides Type: general – SubjectFull: Polysaccharides Type: general – SubjectFull: Immunoregulation Type: general – SubjectFull: Antioxidants Type: general – SubjectFull: Pharmacology Type: general – SubjectFull: Gut microbiota Type: general – SubjectFull: Neuroprotective agents Type: general – SubjectFull: Antineoplastic agent development Type: general Titles: – TitleFull: The Influence of Monosaccharide Composition on the Bioactivity of Medicinal Plant Polysaccharides. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Fan, Xinhui – PersonEntity: Name: NameFull: Li, Ke – PersonEntity: Name: NameFull: Yang, Maohui – PersonEntity: Name: NameFull: Qin, Xuemei – PersonEntity: Name: NameFull: Li, Zhenyu – PersonEntity: Name: NameFull: Du, Yuguang IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: Apr2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 16616596 Numbering: – Type: volume Value: 27 – Type: issue Value: 7 Titles: – TitleFull: International Journal of Molecular Sciences Type: main |
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