Academic Journal
Development and biomechanical validation of a whole spine–thorax finite element model for quantitative biomechanical analysis.
| Τίτλος: | Development and biomechanical validation of a whole spine–thorax finite element model for quantitative biomechanical analysis. |
|---|---|
| Συγγραφείς: | Li, Junhua, Yu, Yaoshuai, Lin, Yuanxun, Liu, Hongwen, Zhong, Weixing, Tang, Lixin, Chen, Diangu, Ye, Yongliang, Lin, Xiaoguang, Tian, Tianzhao, Li, Yikai |
| Πηγή: | PeerJ; Mar2026, p1-20, 20p |
| Θεματικοί όροι: | Finite element method, Model validation, Stress concentration, Thoracic vertebrae, Biomechanics, Computed tomography, Torsional load |
| Περίληψη: | Objective: To develop a high-fidelity three-dimensional finite element model of the whole spine–thorax complex based on high-resolution computed tomography (CT) images of a healthy adult male, and to perform initial validation under representative loading conditions for quantitative analysis of load transmission, coupled motion, and stress distribution. We hypothesized that the model would reproduce published quasi-static segmental moment–rotation behavior and cadaveric thoracic impact responses within acceptable error ranges. Methods: High-resolution CT data of one healthy adult Chinese male volunteer (25 years; 175 cm; 70 kg) were used to reconstruct detailed anatomical structures, including vertebrae, intervertebral discs, ribs, costal cartilage, sternum, ligaments, respiratory muscles, lungs, and heart. Material properties were assigned based on literature data, and nonlinear contacts were defined among articular and cartilaginous structures. Model validation was carried out using two scenarios: pure-moment loading of the T12–L1 functional spinal unit and a frontal chest impact simulation, with the numerical responses compared against available experimental and cadaveric data. Results: The T12–L1 moment–rotation curves agreed well with published biomechanical ranges, and the frontal impact simulation produced a peak force (3,270 N) and chest compression (79 mm) closely matching experimental results (3,453 N and 80 mm), with errors of 5.3% and 1.25%, respectively. Conclusions: The finite element model reproduced static and dynamic responses of the spine–thorax complex within available experimental ranges for the loading conditions examined, providing an initial, non-invasive platform for investigating load transmission, coupled motion, and stress distribution under physiological, pathological, and interventional conditions. [ABSTRACT FROM AUTHOR] |
| Copyright of PeerJ is the property of PeerJ Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Βάση Δεδομένων: | Complementary Index |
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| Items | – Name: Title Label: Title Group: Ti Data: Development and biomechanical validation of a whole spine–thorax finite element model for quantitative biomechanical analysis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Li%2C+Junhua%22">Li, Junhua</searchLink><br /><searchLink fieldCode="AR" term="%22Yu%2C+Yaoshuai%22">Yu, Yaoshuai</searchLink><br /><searchLink fieldCode="AR" term="%22Lin%2C+Yuanxun%22">Lin, Yuanxun</searchLink><br /><searchLink fieldCode="AR" term="%22Liu%2C+Hongwen%22">Liu, Hongwen</searchLink><br /><searchLink fieldCode="AR" term="%22Zhong%2C+Weixing%22">Zhong, Weixing</searchLink><br /><searchLink fieldCode="AR" term="%22Tang%2C+Lixin%22">Tang, Lixin</searchLink><br /><searchLink fieldCode="AR" term="%22Chen%2C+Diangu%22">Chen, Diangu</searchLink><br /><searchLink fieldCode="AR" term="%22Ye%2C+Yongliang%22">Ye, Yongliang</searchLink><br /><searchLink fieldCode="AR" term="%22Lin%2C+Xiaoguang%22">Lin, Xiaoguang</searchLink><br /><searchLink fieldCode="AR" term="%22Tian%2C+Tianzhao%22">Tian, Tianzhao</searchLink><br /><searchLink fieldCode="AR" term="%22Li%2C+Yikai%22">Li, Yikai</searchLink> – Name: TitleSource Label: Source Group: Src Data: PeerJ; Mar2026, p1-20, 20p – Name: Subject Label: Subject Terms Group: Su Data: <searchLink fieldCode="DE" term="%22Finite+element+method%22">Finite element method</searchLink><br /><searchLink fieldCode="DE" term="%22Model+validation%22">Model validation</searchLink><br /><searchLink fieldCode="DE" term="%22Stress+concentration%22">Stress concentration</searchLink><br /><searchLink fieldCode="DE" term="%22Thoracic+vertebrae%22">Thoracic vertebrae</searchLink><br /><searchLink fieldCode="DE" term="%22Biomechanics%22">Biomechanics</searchLink><br /><searchLink fieldCode="DE" term="%22Computed+tomography%22">Computed tomography</searchLink><br /><searchLink fieldCode="DE" term="%22Torsional+load%22">Torsional load</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Objective: To develop a high-fidelity three-dimensional finite element model of the whole spine–thorax complex based on high-resolution computed tomography (CT) images of a healthy adult male, and to perform initial validation under representative loading conditions for quantitative analysis of load transmission, coupled motion, and stress distribution. We hypothesized that the model would reproduce published quasi-static segmental moment–rotation behavior and cadaveric thoracic impact responses within acceptable error ranges. Methods: High-resolution CT data of one healthy adult Chinese male volunteer (25 years; 175 cm; 70 kg) were used to reconstruct detailed anatomical structures, including vertebrae, intervertebral discs, ribs, costal cartilage, sternum, ligaments, respiratory muscles, lungs, and heart. Material properties were assigned based on literature data, and nonlinear contacts were defined among articular and cartilaginous structures. Model validation was carried out using two scenarios: pure-moment loading of the T12–L1 functional spinal unit and a frontal chest impact simulation, with the numerical responses compared against available experimental and cadaveric data. Results: The T12–L1 moment–rotation curves agreed well with published biomechanical ranges, and the frontal impact simulation produced a peak force (3,270 N) and chest compression (79 mm) closely matching experimental results (3,453 N and 80 mm), with errors of 5.3% and 1.25%, respectively. Conclusions: The finite element model reproduced static and dynamic responses of the spine–thorax complex within available experimental ranges for the loading conditions examined, providing an initial, non-invasive platform for investigating load transmission, coupled motion, and stress distribution under physiological, pathological, and interventional conditions. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Group: Ab Data: <i>Copyright of PeerJ is the property of PeerJ Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.7717/peerj.20961 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 20 StartPage: 1 Subjects: – SubjectFull: Finite element method Type: general – SubjectFull: Model validation Type: general – SubjectFull: Stress concentration Type: general – SubjectFull: Thoracic vertebrae Type: general – SubjectFull: Biomechanics Type: general – SubjectFull: Computed tomography Type: general – SubjectFull: Torsional load Type: general Titles: – TitleFull: Development and biomechanical validation of a whole spine–thorax finite element model for quantitative biomechanical analysis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Li, Junhua – PersonEntity: Name: NameFull: Yu, Yaoshuai – PersonEntity: Name: NameFull: Lin, Yuanxun – PersonEntity: Name: NameFull: Liu, Hongwen – PersonEntity: Name: NameFull: Zhong, Weixing – PersonEntity: Name: NameFull: Tang, Lixin – PersonEntity: Name: NameFull: Chen, Diangu – PersonEntity: Name: NameFull: Ye, Yongliang – PersonEntity: Name: NameFull: Lin, Xiaoguang – PersonEntity: Name: NameFull: Tian, Tianzhao – PersonEntity: Name: NameFull: Li, Yikai IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: Mar2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 21678359 Titles: – TitleFull: PeerJ Type: main |
| ResultId | 1 |