Academic Journal
Dietary Patterns of Docosahexaenoic Acid Intake and Supplementation from Pregnancy Through Childhood with a Focus on Low- and Middle-Income Countries: A Narrative Review of Implications for Child Health.
| Τίτλος: | Dietary Patterns of Docosahexaenoic Acid Intake and Supplementation from Pregnancy Through Childhood with a Focus on Low- and Middle-Income Countries: A Narrative Review of Implications for Child Health. |
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| Συγγραφείς: | Valle-Valdez, Brenda, Terrazas-Lopez, Xochitl, Gonzalez-Rocha, Alejandra, Astiazaran-Garcia, Humberto, Armenta-Guirado, Brianda |
| Πηγή: | Nutrients; Dec2025, Vol. 17 Issue 24, p3931, 29p |
| Περίληψη: | Docosahexaenoic acid (DHA) is a long-chain omega-3 fatty acid essential for neurodevelopment, immune regulation, and key physiological functions during early life. In low- and middle-income countries (LMICs), limited access to DHA-rich foods contributes to disparities in intake and health outcomes. This narrative review describes the current evidence on dietary patterns of DHA intake and supplementation from pregnancy through childhood in LMICs and highlights the implications of these patterns for child health. The review is based on a systematic search conducted in PubMed using Medical Subject Heading (MeSH) terms related to DHA, dietary patterns, health outcomes, and LMICs. Studies published between 2014 and 2025 were screened using Covidence software. Eligible studies included observational, interventional, and review designs that reported DHA through dietary intake, supplementation, or measurement in biological samples during pregnancy, lactation, infancy, or childhood. Data extraction followed the PICOS (Population, Intervention, Comparison, Outcome, Study Design) framework. A total of 76 studies were included. Across LMICs, DHA intake was consistently insufficient among pregnant and lactating women, infants, and children. Reported dietary sources were generally low in DHA content. Intake or supplementation was associated with neurodevelopment, immune response, pregnancy outcomes, and cardiometabolic health, although findings were sometimes mixed or modified by gene–environment interactions. Results varied by study design, contextual factors, income level, and geographic access. Large gaps remain in nationally representative intake data. Despite its physiological relevance, DHA intake remains inadequate in LMICs during early life. This review underscores the importance of improving DHA intake in vulnerable populations and identifies evidence gaps to guide future research and inform context-specific nutrition strategies. [ABSTRACT FROM AUTHOR] |
| Copyright of Nutrients is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Βάση Δεδομένων: | Complementary Index |
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| Items | – Name: Title Label: Title Group: Ti Data: Dietary Patterns of Docosahexaenoic Acid Intake and Supplementation from Pregnancy Through Childhood with a Focus on Low- and Middle-Income Countries: A Narrative Review of Implications for Child Health. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Valle-Valdez%2C+Brenda%22">Valle-Valdez, Brenda</searchLink><br /><searchLink fieldCode="AR" term="%22Terrazas-Lopez%2C+Xochitl%22">Terrazas-Lopez, Xochitl</searchLink><br /><searchLink fieldCode="AR" term="%22Gonzalez-Rocha%2C+Alejandra%22">Gonzalez-Rocha, Alejandra</searchLink><br /><searchLink fieldCode="AR" term="%22Astiazaran-Garcia%2C+Humberto%22">Astiazaran-Garcia, Humberto</searchLink><br /><searchLink fieldCode="AR" term="%22Armenta-Guirado%2C+Brianda%22">Armenta-Guirado, Brianda</searchLink> – Name: TitleSource Label: Source Group: Src Data: Nutrients; Dec2025, Vol. 17 Issue 24, p3931, 29p – Name: Abstract Label: Abstract Group: Ab Data: Docosahexaenoic acid (DHA) is a long-chain omega-3 fatty acid essential for neurodevelopment, immune regulation, and key physiological functions during early life. In low- and middle-income countries (LMICs), limited access to DHA-rich foods contributes to disparities in intake and health outcomes. This narrative review describes the current evidence on dietary patterns of DHA intake and supplementation from pregnancy through childhood in LMICs and highlights the implications of these patterns for child health. The review is based on a systematic search conducted in PubMed using Medical Subject Heading (MeSH) terms related to DHA, dietary patterns, health outcomes, and LMICs. Studies published between 2014 and 2025 were screened using Covidence software. Eligible studies included observational, interventional, and review designs that reported DHA through dietary intake, supplementation, or measurement in biological samples during pregnancy, lactation, infancy, or childhood. Data extraction followed the PICOS (Population, Intervention, Comparison, Outcome, Study Design) framework. A total of 76 studies were included. Across LMICs, DHA intake was consistently insufficient among pregnant and lactating women, infants, and children. Reported dietary sources were generally low in DHA content. Intake or supplementation was associated with neurodevelopment, immune response, pregnancy outcomes, and cardiometabolic health, although findings were sometimes mixed or modified by gene–environment interactions. Results varied by study design, contextual factors, income level, and geographic access. Large gaps remain in nationally representative intake data. Despite its physiological relevance, DHA intake remains inadequate in LMICs during early life. This review underscores the importance of improving DHA intake in vulnerable populations and identifies evidence gaps to guide future research and inform context-specific nutrition strategies. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Group: Ab Data: <i>Copyright of Nutrients is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3390/nu17243931 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 29 StartPage: 3931 Titles: – TitleFull: Dietary Patterns of Docosahexaenoic Acid Intake and Supplementation from Pregnancy Through Childhood with a Focus on Low- and Middle-Income Countries: A Narrative Review of Implications for Child Health. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Valle-Valdez, Brenda – PersonEntity: Name: NameFull: Terrazas-Lopez, Xochitl – PersonEntity: Name: NameFull: Gonzalez-Rocha, Alejandra – PersonEntity: Name: NameFull: Astiazaran-Garcia, Humberto – PersonEntity: Name: NameFull: Armenta-Guirado, Brianda IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 12 Text: Dec2025 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 20726643 Numbering: – Type: volume Value: 17 – Type: issue Value: 24 Titles: – TitleFull: Nutrients Type: main |
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