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Clinical Value of Transcutaneous PCO 2 in Free Flap Blood Supply.

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Τίτλος: Clinical Value of Transcutaneous PCO 2 in Free Flap Blood Supply.
Συγγραφείς: Liu, Fangfang, Han, Nannan, Wang, Lei, Dong, Jinxiu, Ruan, Min, Ying, Youguo
Πηγή: Journal of Clinical Medicine; Oct2025, Vol. 14 Issue 19, p7112, 12p
Θεματικοί όροι: Surgical flaps, Blood flow, Aerobic metabolism, Blood flow measurement, Prognosis, Oral cancer
Περίληψη: Background: Transcutaneous PCO2 (TcPCO2) effectively represents the partial pressure of carbon dioxide in deep tissues, providing us with more accurate information regarding deep tissue perfusion and oxygen metabolism. Based on this, we aimed to explore the clinical value of TcPCO2 in assessing free flap blood supply during oral cancer surgery. Methods: A total of 27 patients undergoing oral cancer reconstruction with free flap reconstruction were enrolled. For enrolled patients, continuous monitoring was conducted before, during, and after free flap transplantation surgery. Results: A total of 121 measurements were taken, comprising 93 instances in the normal flap group and 28 instances in the insufficient flap group. The TcPCO2 levels were significantly higher and transcutaneous PO2 (TcPO2) levels were lower in the insufficient group (p < 0.001). The cutoff values for TcPCO2 and TcPO2, calculated using the Youden index, were 66 mmHg and 16 mmHg, respectively. TcPCO2 exhibits high specificity in monitoring the blood supply of free flaps. The area under the ROC curve (AUC) for TcPCO2 in predicting insufficient flap perfusion was calculated to be 0.912. Conclusions: TcPCO2 demonstrates high specificity in assessing blood supply in free flaps for patients undergoing oral cancer surgery and has diagnostic significance for early identification of insufficient flap. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Clinical Medicine is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Βάση Δεδομένων: Complementary Index
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  Data: Clinical Value of Transcutaneous PCO 2 in Free Flap Blood Supply.
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  Data: Journal of Clinical Medicine; Oct2025, Vol. 14 Issue 19, p7112, 12p
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  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Surgical+flaps%22&quot;&gt;Surgical flaps&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Blood+flow%22&quot;&gt;Blood flow&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Aerobic+metabolism%22&quot;&gt;Aerobic metabolism&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Blood+flow+measurement%22&quot;&gt;Blood flow measurement&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Prognosis%22&quot;&gt;Prognosis&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Oral+cancer%22&quot;&gt;Oral cancer&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Transcutaneous PCO&lt;subscript&gt;2&lt;/subscript&gt; (TcPCO&lt;subscript&gt;2&lt;/subscript&gt;) effectively represents the partial pressure of carbon dioxide in deep tissues, providing us with more accurate information regarding deep tissue perfusion and oxygen metabolism. Based on this, we aimed to explore the clinical value of TcPCO&lt;subscript&gt;2&lt;/subscript&gt; in assessing free flap blood supply during oral cancer surgery. Methods: A total of 27 patients undergoing oral cancer reconstruction with free flap reconstruction were enrolled. For enrolled patients, continuous monitoring was conducted before, during, and after free flap transplantation surgery. Results: A total of 121 measurements were taken, comprising 93 instances in the normal flap group and 28 instances in the insufficient flap group. The TcPCO&lt;subscript&gt;2&lt;/subscript&gt; levels were significantly higher and transcutaneous PO&lt;subscript&gt;2&lt;/subscript&gt; (TcPO&lt;subscript&gt;2&lt;/subscript&gt;) levels were lower in the insufficient group (p &lt; 0.001). The cutoff values for TcPCO&lt;subscript&gt;2&lt;/subscript&gt; and TcPO&lt;subscript&gt;2&lt;/subscript&gt;, calculated using the Youden index, were 66 mmHg and 16 mmHg, respectively. TcPCO&lt;subscript&gt;2&lt;/subscript&gt; exhibits high specificity in monitoring the blood supply of free flaps. The area under the ROC curve (AUC) for TcPCO&lt;subscript&gt;2&lt;/subscript&gt; in predicting insufficient flap perfusion was calculated to be 0.912. Conclusions: TcPCO&lt;subscript&gt;2&lt;/subscript&gt; demonstrates high specificity in assessing blood supply in free flaps for patients undergoing oral cancer surgery and has diagnostic significance for early identification of insufficient flap. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label:
  Group: Ab
  Data: &lt;i&gt;Copyright of Journal of Clinical Medicine is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.3390/jcm14197112
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 12
        StartPage: 7112
    Subjects:
      – SubjectFull: Surgical flaps
        Type: general
      – SubjectFull: Blood flow
        Type: general
      – SubjectFull: Aerobic metabolism
        Type: general
      – SubjectFull: Blood flow measurement
        Type: general
      – SubjectFull: Prognosis
        Type: general
      – SubjectFull: Oral cancer
        Type: general
    Titles:
      – TitleFull: Clinical Value of Transcutaneous PCO 2 in Free Flap Blood Supply.
        Type: main
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          Name:
            NameFull: Liu, Fangfang
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            NameFull: Han, Nannan
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            NameFull: Wang, Lei
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            NameFull: Dong, Jinxiu
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            NameFull: Ruan, Min
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            NameFull: Ying, Youguo
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          Dates:
            – D: 01
              M: 10
              Text: Oct2025
              Type: published
              Y: 2025
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              Value: 20770383
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              Value: 14
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              Value: 19
          Titles:
            – TitleFull: Journal of Clinical Medicine
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