Academic Journal

Functional near-infrared spectroscopy characteristics in children with autism spectrum disorder under animated video modeling therapy.

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Τίτλος: Functional near-infrared spectroscopy characteristics in children with autism spectrum disorder under animated video modeling therapy.
Συγγραφείς: Zhu, Chuanhua, Li, Hongwei, Zhang, Lina, Liu, Yonglu, Zhang, Yangyang, Huang, Binbin, Li, Wei
Πηγή: Frontiers in Neurology; 2025, p1-11, 11p
Θεματικοί όροι: Autism spectrum disorders, Near infrared spectroscopy, Visual perception, Therapeutics, School children, Cognitive psychology, Human information processing, Functional connectivity
Περίληψη: Objective: To investigate the impact of animated video modeling (AVM) on the brain function of children with autism spectrum disorder (ASD) using functional near-infrared spectroscopy (fNIRS). Methods: Fifteen children with ASD and 15 matched typically developing (TD) controls were enrolled. fNIRS was used to obtain 8-min data in quiet and visually stimulated states, with the dorsolateral prefrontal cortex, medial prefrontal cortex (mPFC), and bilateral occipital lobe as regions of interest (ROIs). Based on the concentration of oxygenated hemoglobin (HbO2) over time, correlation coefficient analysis was performed to calculate functional connection strength, and the intergroup disparity was compared. Result: The ASD group showed significantly lower functional connection strength. Comparison of the ROI–ROI functional connectivity strength revealed significant differences in connectivity patterns of the right dorsolateral prefrontal lobe (RDLPFC), left dorsolateral prefrontal lobe (LDLPFC), mPFC, right occipital lobe (ROL), and left occipital lobe (LOL) with other brain regions. Extremely significant differences were found between the RDLPFC/RPMC, ROL/RPMC, LOL/RPMC, and LOL/LIPL. The functional connectivity strength of children with ASD was significantly higher during visual stimulation than during the quiet test. Comparison between the ROI–ROI functional connectivity strengths revealed significant differences in the connectivity strength of the RDLPFC/LOL, LDLPFC/LIPL, mPFC/RPMC, mPFC/LPMC, mPFC/LIPL, ROL/RPM, ROL. RIPL, ROL/LIPL, and LOL/LIPL. Extremely significant differences were observed between the ROL/RPMC and ROL/RIPL. Conclusion: Animated video modeling can improve visual perception and information processing in children with ASD, by strengthening the functional connectivity between the occipital and inferior parietal cortices. [ABSTRACT FROM AUTHOR]
Copyright of Frontiers in Neurology is the property of Frontiers Media S.A. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Label: Title
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  Data: Functional near-infrared spectroscopy characteristics in children with autism spectrum disorder under animated video modeling therapy.
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  Data: <searchLink fieldCode="AR" term="%22Zhu%2C+Chuanhua%22">Zhu, Chuanhua</searchLink><br /><searchLink fieldCode="AR" term="%22Li%2C+Hongwei%22">Li, Hongwei</searchLink><br /><searchLink fieldCode="AR" term="%22Zhang%2C+Lina%22">Zhang, Lina</searchLink><br /><searchLink fieldCode="AR" term="%22Liu%2C+Yonglu%22">Liu, Yonglu</searchLink><br /><searchLink fieldCode="AR" term="%22Zhang%2C+Yangyang%22">Zhang, Yangyang</searchLink><br /><searchLink fieldCode="AR" term="%22Huang%2C+Binbin%22">Huang, Binbin</searchLink><br /><searchLink fieldCode="AR" term="%22Li%2C+Wei%22">Li, Wei</searchLink>
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  Data: Frontiers in Neurology; 2025, p1-11, 11p
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  Data: <searchLink fieldCode="DE" term="%22Autism+spectrum+disorders%22">Autism spectrum disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Near+infrared+spectroscopy%22">Near infrared spectroscopy</searchLink><br /><searchLink fieldCode="DE" term="%22Visual+perception%22">Visual perception</searchLink><br /><searchLink fieldCode="DE" term="%22Therapeutics%22">Therapeutics</searchLink><br /><searchLink fieldCode="DE" term="%22School+children%22">School children</searchLink><br /><searchLink fieldCode="DE" term="%22Cognitive+psychology%22">Cognitive psychology</searchLink><br /><searchLink fieldCode="DE" term="%22Human+information+processing%22">Human information processing</searchLink><br /><searchLink fieldCode="DE" term="%22Functional+connectivity%22">Functional connectivity</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Objective: To investigate the impact of animated video modeling (AVM) on the brain function of children with autism spectrum disorder (ASD) using functional near-infrared spectroscopy (fNIRS). Methods: Fifteen children with ASD and 15 matched typically developing (TD) controls were enrolled. fNIRS was used to obtain 8-min data in quiet and visually stimulated states, with the dorsolateral prefrontal cortex, medial prefrontal cortex (mPFC), and bilateral occipital lobe as regions of interest (ROIs). Based on the concentration of oxygenated hemoglobin (HbO<subscript>2</subscript>) over time, correlation coefficient analysis was performed to calculate functional connection strength, and the intergroup disparity was compared. Result: The ASD group showed significantly lower functional connection strength. Comparison of the ROI–ROI functional connectivity strength revealed significant differences in connectivity patterns of the right dorsolateral prefrontal lobe (RDLPFC), left dorsolateral prefrontal lobe (LDLPFC), mPFC, right occipital lobe (ROL), and left occipital lobe (LOL) with other brain regions. Extremely significant differences were found between the RDLPFC/RPMC, ROL/RPMC, LOL/RPMC, and LOL/LIPL. The functional connectivity strength of children with ASD was significantly higher during visual stimulation than during the quiet test. Comparison between the ROI–ROI functional connectivity strengths revealed significant differences in the connectivity strength of the RDLPFC/LOL, LDLPFC/LIPL, mPFC/RPMC, mPFC/LPMC, mPFC/LIPL, ROL/RPM, ROL. RIPL, ROL/LIPL, and LOL/LIPL. Extremely significant differences were observed between the ROL/RPMC and ROL/RIPL. Conclusion: Animated video modeling can improve visual perception and information processing in children with ASD, by strengthening the functional connectivity between the occipital and inferior parietal cortices. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label:
  Group: Ab
  Data: <i>Copyright of Frontiers in Neurology is the property of Frontiers Media S.A. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.3389/fneur.2025.1590185
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        Text: English
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        Type: general
      – SubjectFull: Near infrared spectroscopy
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      – SubjectFull: Visual perception
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      – SubjectFull: Therapeutics
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      – TitleFull: Functional near-infrared spectroscopy characteristics in children with autism spectrum disorder under animated video modeling therapy.
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              Text: 2025
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