Academic Journal
Evaluation of Insecticide Treated Military Uniforms in Combination with DoD Approved Insect Repellents Against Sand Fly Bites Using a Hairless Guinea Pig Model.
| Τίτλος: | Evaluation of Insecticide Treated Military Uniforms in Combination with DoD Approved Insect Repellents Against Sand Fly Bites Using a Hairless Guinea Pig Model. |
|---|---|
| Συγγραφείς: | Case, Jamie R., Bender, Kathryn, Pascini, Tales, Perazzo, Leah, Maheswaran, Durga, Raiciulescu, Sorana, Chagas, Andrezza, Perry, Melynda, Burrows, Matthew, Wanja, Elizabeth, Murphy, Jittawadee, Rowland, Tobin |
| Πηγή: | Medical Journal, US Army Medical Center of Excellence (MEDCoE); Oct-Dec2024, p49-56, 8p |
| Θεματικοί όροι: | Sand flies, Trypanosomiasis, Insect baits & repellents, Military uniforms, Phlebotomus |
| Περίληψη: | Sand flies are small, blood feeding arthropods responsible for the transmission of Leishmania protozoa, the causative agent of Leishmaniasis which can affect humans. This study evaluated the efficacy of permethrin-treated, etofenprox-treated, and untreated Flame-Resistant Army Combat Uniform (FRACU) materials, in preventing sand fly, Phlebotomus papatasi, bites when challenged in the absence or presence of military authorized topical repellents i. e. diethyl-m-toluamide -DEET, Ethyl butylacetylaminoproprionate commonly referred to as Insect Repellent 3535-IR3535, and picaridin, when applied to the exposed skin of hairless guinea pigs. Uniform fabrics used in sand fly bite challenges were exposed to 1, 20, and 50 washes prior to the start of this study. Our findings demonstrate the hairless guinea pig as a suitable animal model that supports sand fly host-seeking behavior and could replace the use of humans in treated uniform bite protection studies. Probing was not recorded; however, the presence or absence of blood was examined 24 hours after exposure by crushing the sand fly on white filter paper. Statistically significant differences were observed in the percentage of blood fed sand flies between untreated and both treated uniforms (etofenprox and permethrin). However, no significant difference was found between number of wash treatments. Bite protection was observed when topical repellents (DEET, Picaridin, and IR355) were applied to the host exposed skin. The trends observed in sand fly knockdown (above 60% at 1h) vary with multiple wash treatments suggesting that sand flies were potentially in contact with treated uniforms even in the presence of topical repellents. Also, a synergistic effect (treated uniform and repellents) should be considered. This assessment highlights the bite protection offered by military treated uniforms and repellents against sand fly bites and disease transmission. Therefore, the use of topical repellents along with treated uniforms remains highly recommended. [ABSTRACT FROM AUTHOR] |
| Copyright of Medical Journal, US Army Medical Center of Excellence (MEDCoE) is the property of U.S. Army Medical Department and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Βάση Δεδομένων: | Complementary Index |
| FullText | Text: Availability: 0 |
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| Header | DbId: edb DbLabel: Complementary Index An: 181594936 RelevancyScore: 966 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 965.718994140625 |
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| Items | – Name: Title Label: Title Group: Ti Data: Evaluation of Insecticide Treated Military Uniforms in Combination with DoD Approved Insect Repellents Against Sand Fly Bites Using a Hairless Guinea Pig Model. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Case%2C+Jamie+R%2E%22">Case, Jamie R.</searchLink><br /><searchLink fieldCode="AR" term="%22Bender%2C+Kathryn%22">Bender, Kathryn</searchLink><br /><searchLink fieldCode="AR" term="%22Pascini%2C+Tales%22">Pascini, Tales</searchLink><br /><searchLink fieldCode="AR" term="%22Perazzo%2C+Leah%22">Perazzo, Leah</searchLink><br /><searchLink fieldCode="AR" term="%22Maheswaran%2C+Durga%22">Maheswaran, Durga</searchLink><br /><searchLink fieldCode="AR" term="%22Raiciulescu%2C+Sorana%22">Raiciulescu, Sorana</searchLink><br /><searchLink fieldCode="AR" term="%22Chagas%2C+Andrezza%22">Chagas, Andrezza</searchLink><br /><searchLink fieldCode="AR" term="%22Perry%2C+Melynda%22">Perry, Melynda</searchLink><br /><searchLink fieldCode="AR" term="%22Burrows%2C+Matthew%22">Burrows, Matthew</searchLink><br /><searchLink fieldCode="AR" term="%22Wanja%2C+Elizabeth%22">Wanja, Elizabeth</searchLink><br /><searchLink fieldCode="AR" term="%22Murphy%2C+Jittawadee%22">Murphy, Jittawadee</searchLink><br /><searchLink fieldCode="AR" term="%22Rowland%2C+Tobin%22">Rowland, Tobin</searchLink> – Name: TitleSource Label: Source Group: Src Data: Medical Journal, US Army Medical Center of Excellence (MEDCoE); Oct-Dec2024, p49-56, 8p – Name: Subject Label: Subject Terms Group: Su Data: <searchLink fieldCode="DE" term="%22Sand+flies%22">Sand flies</searchLink><br /><searchLink fieldCode="DE" term="%22Trypanosomiasis%22">Trypanosomiasis</searchLink><br /><searchLink fieldCode="DE" term="%22Insect+baits+%26+repellents%22">Insect baits & repellents</searchLink><br /><searchLink fieldCode="DE" term="%22Military+uniforms%22">Military uniforms</searchLink><br /><searchLink fieldCode="DE" term="%22Phlebotomus%22">Phlebotomus</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Sand flies are small, blood feeding arthropods responsible for the transmission of Leishmania protozoa, the causative agent of Leishmaniasis which can affect humans. This study evaluated the efficacy of permethrin-treated, etofenprox-treated, and untreated Flame-Resistant Army Combat Uniform (FRACU) materials, in preventing sand fly, Phlebotomus papatasi, bites when challenged in the absence or presence of military authorized topical repellents i. e. diethyl-m-toluamide -DEET, Ethyl butylacetylaminoproprionate commonly referred to as Insect Repellent 3535-IR3535, and picaridin, when applied to the exposed skin of hairless guinea pigs. Uniform fabrics used in sand fly bite challenges were exposed to 1, 20, and 50 washes prior to the start of this study. Our findings demonstrate the hairless guinea pig as a suitable animal model that supports sand fly host-seeking behavior and could replace the use of humans in treated uniform bite protection studies. Probing was not recorded; however, the presence or absence of blood was examined 24 hours after exposure by crushing the sand fly on white filter paper. Statistically significant differences were observed in the percentage of blood fed sand flies between untreated and both treated uniforms (etofenprox and permethrin). However, no significant difference was found between number of wash treatments. Bite protection was observed when topical repellents (DEET, Picaridin, and IR355) were applied to the host exposed skin. The trends observed in sand fly knockdown (above 60% at 1h) vary with multiple wash treatments suggesting that sand flies were potentially in contact with treated uniforms even in the presence of topical repellents. Also, a synergistic effect (treated uniform and repellents) should be considered. This assessment highlights the bite protection offered by military treated uniforms and repellents against sand fly bites and disease transmission. Therefore, the use of topical repellents along with treated uniforms remains highly recommended. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Group: Ab Data: <i>Copyright of Medical Journal, US Army Medical Center of Excellence (MEDCoE) is the property of U.S. Army Medical Department and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edb&AN=181594936 |
| RecordInfo | BibRecord: BibEntity: Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 49 Subjects: – SubjectFull: Sand flies Type: general – SubjectFull: Trypanosomiasis Type: general – SubjectFull: Insect baits & repellents Type: general – SubjectFull: Military uniforms Type: general – SubjectFull: Phlebotomus Type: general Titles: – TitleFull: Evaluation of Insecticide Treated Military Uniforms in Combination with DoD Approved Insect Repellents Against Sand Fly Bites Using a Hairless Guinea Pig Model. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Case, Jamie R. – PersonEntity: Name: NameFull: Bender, Kathryn – PersonEntity: Name: NameFull: Pascini, Tales – PersonEntity: Name: NameFull: Perazzo, Leah – PersonEntity: Name: NameFull: Maheswaran, Durga – PersonEntity: Name: NameFull: Raiciulescu, Sorana – PersonEntity: Name: NameFull: Chagas, Andrezza – PersonEntity: Name: NameFull: Perry, Melynda – PersonEntity: Name: NameFull: Burrows, Matthew – PersonEntity: Name: NameFull: Wanja, Elizabeth – PersonEntity: Name: NameFull: Murphy, Jittawadee – PersonEntity: Name: NameFull: Rowland, Tobin IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: Oct-Dec2024 Type: published Y: 2024 Identifiers: – Type: issn-print Value: 26943581 Titles: – TitleFull: Medical Journal, US Army Medical Center of Excellence (MEDCoE) Type: main |
| ResultId | 1 |