Academic Journal
Comparative Genomics of All Three Campylobacter sputorum Biovars and a Novel Cattle-Associated C. sputorum Clade.
| Τίτλος: | Comparative Genomics of All Three Campylobacter sputorum Biovars and a Novel Cattle-Associated C. sputorum Clade. |
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| Συγγραφείς: | Miller, William G., Yee, Emma, Chapman, Mary H., Bono, James L. |
| Πηγή: | Genome Biology & Evolution; Jun2017, Vol. 9 Issue 6, p1513-1518, 6p |
| Θεματικοί όροι: | Campylobacter, Genomics, Urease genetics, Comparative genomics, Catalase genetics |
| Περίληψη: | Campylobacter sputorumis anonthermotolerantcampylobacter that is primarily isolated from food animals such as cattle andsheep. C. sputorum is also infrequently associated with human illness. Based on catalase and urease activity, three biovars are currently recognized within C. sputorum:bv. sputorum(catalasenegative, urease negative), bv. fecalis (catalasepositive, urease negative), and bv. paraureolyticus (catalase negative, urease positive). A multi-locus sequence typing (MLST)methodwas recently constructed for C. sputorum. MLST typing of several cattle-associated C. sputorum isolates suggested that they are members of a divergent C. sputorum clade. Although catalase positive, and thus technically bv. fecalis, the taxonomic position of these strains could not be determined solely by MLST. To further characterize C. sputorum, the genomes of four strains, representing all three biovars and the divergent clade, were sequenced to completion. Here we present a comparative genomic analysis of the four C. sputorum genomes. This analysis indicates that the three biovars and the cattle-associated strains are highly related at the genome level with similarities in gene content. Furthermore, the four genomes are strongly syntenic with one or two minor inversions. However, substantial differences in gene content were observed among the three biovars. Finally, although the strain representing the cattle-associated isolateswas shown to be C. sputorum, it is possible that this strain is amember of a novel C. sputorum subspecies; thus, these cattle-associated strains may form a second taxon within C. sputorum. [ABSTRACT FROM AUTHOR] |
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| Βάση Δεδομένων: | Complementary Index |
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| Header | DbId: edb DbLabel: Complementary Index An: 124368141 RelevancyScore: 853 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 853.477783203125 |
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| Items | – Name: Title Label: Title Group: Ti Data: Comparative Genomics of All Three Campylobacter sputorum Biovars and a Novel Cattle-Associated C. sputorum Clade. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Miller%2C+William+G%2E%22">Miller, William G.</searchLink><br /><searchLink fieldCode="AR" term="%22Yee%2C+Emma%22">Yee, Emma</searchLink><br /><searchLink fieldCode="AR" term="%22Chapman%2C+Mary+H%2E%22">Chapman, Mary H.</searchLink><br /><searchLink fieldCode="AR" term="%22Bono%2C+James+L%2E%22">Bono, James L.</searchLink> – Name: TitleSource Label: Source Group: Src Data: Genome Biology & Evolution; Jun2017, Vol. 9 Issue 6, p1513-1518, 6p – Name: Subject Label: Subject Terms Group: Su Data: <searchLink fieldCode="DE" term="%22Campylobacter%22">Campylobacter</searchLink><br /><searchLink fieldCode="DE" term="%22Genomics%22">Genomics</searchLink><br /><searchLink fieldCode="DE" term="%22Urease+genetics%22">Urease genetics</searchLink><br /><searchLink fieldCode="DE" term="%22Comparative+genomics%22">Comparative genomics</searchLink><br /><searchLink fieldCode="DE" term="%22Catalase+genetics%22">Catalase genetics</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Campylobacter sputorumis anonthermotolerantcampylobacter that is primarily isolated from food animals such as cattle andsheep. C. sputorum is also infrequently associated with human illness. Based on catalase and urease activity, three biovars are currently recognized within C. sputorum:bv. sputorum(catalasenegative, urease negative), bv. fecalis (catalasepositive, urease negative), and bv. paraureolyticus (catalase negative, urease positive). A multi-locus sequence typing (MLST)methodwas recently constructed for C. sputorum. MLST typing of several cattle-associated C. sputorum isolates suggested that they are members of a divergent C. sputorum clade. Although catalase positive, and thus technically bv. fecalis, the taxonomic position of these strains could not be determined solely by MLST. To further characterize C. sputorum, the genomes of four strains, representing all three biovars and the divergent clade, were sequenced to completion. Here we present a comparative genomic analysis of the four C. sputorum genomes. This analysis indicates that the three biovars and the cattle-associated strains are highly related at the genome level with similarities in gene content. Furthermore, the four genomes are strongly syntenic with one or two minor inversions. However, substantial differences in gene content were observed among the three biovars. Finally, although the strain representing the cattle-associated isolateswas shown to be C. sputorum, it is possible that this strain is amember of a novel C. sputorum subspecies; thus, these cattle-associated strains may form a second taxon within C. sputorum. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Group: Ab Data: <i>Copyright of Genome Biology & Evolution is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1093/gbe/evx112 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 6 StartPage: 1513 Subjects: – SubjectFull: Campylobacter Type: general – SubjectFull: Genomics Type: general – SubjectFull: Urease genetics Type: general – SubjectFull: Comparative genomics Type: general – SubjectFull: Catalase genetics Type: general Titles: – TitleFull: Comparative Genomics of All Three Campylobacter sputorum Biovars and a Novel Cattle-Associated C. sputorum Clade. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Miller, William G. – PersonEntity: Name: NameFull: Yee, Emma – PersonEntity: Name: NameFull: Chapman, Mary H. – PersonEntity: Name: NameFull: Bono, James L. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: Jun2017 Type: published Y: 2017 Identifiers: – Type: issn-print Value: 17596653 Numbering: – Type: volume Value: 9 – Type: issue Value: 6 Titles: – TitleFull: Genome Biology & Evolution Type: main |
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