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Consensus on the clinical management, screening-to-treat, and surveillance of Helicobacter pylori infection to improve gastric cancer control on a nationwide scale.

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Title: Consensus on the clinical management, screening-to-treat, and surveillance of Helicobacter pylori infection to improve gastric cancer control on a nationwide scale.
Authors: Sheu, Bor‐Shyang, Wu, Ming‐Shiang, Chiu, Cheng‐Tang, Lo, Jing‐Chuan, Wu, Deng‐Chyang, Liou, Jyh‐Ming, Wu, Chun‐Ying, Cheng, Hsiu‐Chi, Lee, Yi‐Chia, Hsu, Ping‐I, Chang, Chun‐Chao, Chang, Wei‐Lun, Lin, Jaw‐Town
Source: Helicobacter; Jun2017, Vol. 22 Issue 3, pn/a-N.PAG, 15p
Subject Terms: Helicobacter pylori infections, Gastric diseases, Gastrointestinal cancer, Microbial sensitivity tests, Disease prevalence, Prevention
Abstract: Background Previous international consensus statements provided general policies for the management of Helicobacter pylori infection. However, there are geographic differences in the prevalence and antimicrobial resistance of H. pylori, and in the availability of medications and endoscopy. Thus, nationwide or regional consensus statements are needed to improve control of H. pylori infection and gastric cancer. Materials and Methods This consensus statement for management of H. pylori in Taiwan has three major sections: (1) optimal diagnosis and indications; (2) current treatment strategies; and (3) screening-to-treat and surveillance for control of gastric cancer. The literature review emphasized recent data for development of draft statements and determination of levels of evidence. Twenty-five Taiwan experts conducted a consensus conference, by a modified Delphi process, to modify the draft statements. Consensus, defined as an agreement of least 80% of the experts, and recommendation grade were determined by anonymous voting. Results There were 24 consensus statements. Section 1 has seven statements on recommendations for the diagnosis and indications for treatment of H. pylori infection. Section 2 has 10 statements that provide an updated treatment algorithm for first-line, second-line, and third-line regimens. Section 3 has seven statements regarding H. pylori eradication for reducing the risk of gastric cancer, with a cost-benefit analysis. After H. pylori eradication, the consensus highlights the use of endoscopic surveillance and/or chemoprevention to further reduce the burden of gastric cancer. Conclusions This consensus statement has updated recommendations for improving the clinical management of H. pylori infection in areas such as Taiwan, which have high prevalence of H. pylori infection and gastric cancer. [ABSTRACT FROM AUTHOR]
Copyright of Helicobacter is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Complementary Index
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  Data: Consensus on the clinical management, screening-to-treat, and surveillance of Helicobacter pylori infection to improve gastric cancer control on a nationwide scale.
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  Data: <searchLink fieldCode="AR" term="%22Sheu%2C+Bor‐Shyang%22">Sheu, Bor‐Shyang</searchLink><br /><searchLink fieldCode="AR" term="%22Wu%2C+Ming‐Shiang%22">Wu, Ming‐Shiang</searchLink><br /><searchLink fieldCode="AR" term="%22Chiu%2C+Cheng‐Tang%22">Chiu, Cheng‐Tang</searchLink><br /><searchLink fieldCode="AR" term="%22Lo%2C+Jing‐Chuan%22">Lo, Jing‐Chuan</searchLink><br /><searchLink fieldCode="AR" term="%22Wu%2C+Deng‐Chyang%22">Wu, Deng‐Chyang</searchLink><br /><searchLink fieldCode="AR" term="%22Liou%2C+Jyh‐Ming%22">Liou, Jyh‐Ming</searchLink><br /><searchLink fieldCode="AR" term="%22Wu%2C+Chun‐Ying%22">Wu, Chun‐Ying</searchLink><br /><searchLink fieldCode="AR" term="%22Cheng%2C+Hsiu‐Chi%22">Cheng, Hsiu‐Chi</searchLink><br /><searchLink fieldCode="AR" term="%22Lee%2C+Yi‐Chia%22">Lee, Yi‐Chia</searchLink><br /><searchLink fieldCode="AR" term="%22Hsu%2C+Ping‐I%22">Hsu, Ping‐I</searchLink><br /><searchLink fieldCode="AR" term="%22Chang%2C+Chun‐Chao%22">Chang, Chun‐Chao</searchLink><br /><searchLink fieldCode="AR" term="%22Chang%2C+Wei‐Lun%22">Chang, Wei‐Lun</searchLink><br /><searchLink fieldCode="AR" term="%22Lin%2C+Jaw‐Town%22">Lin, Jaw‐Town</searchLink>
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  Data: Helicobacter; Jun2017, Vol. 22 Issue 3, pn/a-N.PAG, 15p
– Name: Subject
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  Data: <searchLink fieldCode="DE" term="%22Helicobacter+pylori+infections%22">Helicobacter pylori infections</searchLink><br /><searchLink fieldCode="DE" term="%22Gastric+diseases%22">Gastric diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Gastrointestinal+cancer%22">Gastrointestinal cancer</searchLink><br /><searchLink fieldCode="DE" term="%22Microbial+sensitivity+tests%22">Microbial sensitivity tests</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+prevalence%22">Disease prevalence</searchLink><br /><searchLink fieldCode="DE" term="%22Prevention%22">Prevention</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background Previous international consensus statements provided general policies for the management of Helicobacter pylori infection. However, there are geographic differences in the prevalence and antimicrobial resistance of H. pylori, and in the availability of medications and endoscopy. Thus, nationwide or regional consensus statements are needed to improve control of H. pylori infection and gastric cancer. Materials and Methods This consensus statement for management of H. pylori in Taiwan has three major sections: (1) optimal diagnosis and indications; (2) current treatment strategies; and (3) screening-to-treat and surveillance for control of gastric cancer. The literature review emphasized recent data for development of draft statements and determination of levels of evidence. Twenty-five Taiwan experts conducted a consensus conference, by a modified Delphi process, to modify the draft statements. Consensus, defined as an agreement of least 80% of the experts, and recommendation grade were determined by anonymous voting. Results There were 24 consensus statements. Section 1 has seven statements on recommendations for the diagnosis and indications for treatment of H. pylori infection. Section 2 has 10 statements that provide an updated treatment algorithm for first-line, second-line, and third-line regimens. Section 3 has seven statements regarding H. pylori eradication for reducing the risk of gastric cancer, with a cost-benefit analysis. After H. pylori eradication, the consensus highlights the use of endoscopic surveillance and/or chemoprevention to further reduce the burden of gastric cancer. Conclusions This consensus statement has updated recommendations for improving the clinical management of H. pylori infection in areas such as Taiwan, which have high prevalence of H. pylori infection and gastric cancer. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label:
  Group: Ab
  Data: <i>Copyright of Helicobacter is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1111/hel.12368
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        Text: English
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        Type: general
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              Text: Jun2017
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