Academic Journal
Impact of a zero-visitation policy on healthcare-associated infections in a non-COVID intensive care unit: A retrospective cohort study.
| Τίτλος: | Impact of a zero-visitation policy on healthcare-associated infections in a non-COVID intensive care unit: A retrospective cohort study. |
|---|---|
| Συγγραφείς: | Ersoy Karka O; Department of Anesthesiology and Reanimation, Faculty of Medicine, Duzce University, Duzce, Turkiye., Akinci D; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Duzce University, Duzce, Turkiye., Sungur MA; Department of Medical Informatics and Biostatistics, Faculty of Medicine, Duzce University, Duzce, Turkiye., Baytar B; Department of Anesthesiology and Reanimation, Faculty of Medicine, Duzce University, Duzce, Turkiye., Caliskan E; Department of Medical Microbiology, Faculty of Medicine, Duzce University, Duzce, Turkiye., Yorulmaz IS; Department of Anesthesiology and Reanimation, Faculty of Medicine, Duzce University, Duzce, Turkiye., Demir Senoglu G; Department of Anesthesiology and Reanimation, Faculty of Medicine, Duzce University, Duzce, Turkiye., Sezen G; Department of Anesthesiology and Reanimation, Faculty of Medicine, Duzce University, Duzce, Turkiye., Demiraran Y; Department of Anesthesiology and Reanimation, Faculty of Medicine, Duzce University, Duzce, Turkiye. |
| Πηγή: | Medicine [Medicine (Baltimore)] 2026 Oct 16; Vol. 105 (42), pp. e51102. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Hagerstown, Md : Lippincott Williams & Wilkins |
| Ιατρικοί όροι (MeSH): | Cross Infection*/epidemiology , Cross Infection*/prevention & control , Intensive Care Units*/statistics & numerical data , COVID-19*/epidemiology , Visitors to Patients*/statistics & numerical data, Infection Control/methods ; Humans ; Retrospective Studies ; Female ; Male ; Middle Aged ; Aged ; Incidence ; SARS-CoV-2 |
| Περίληψη: | The impact of visitor restrictions in intensive care units (ICUs) during the coronavirus disease 2019 (COVID-19) pandemic on healthcare-associated infections (HAIs) remains unclear. This study aimed to compare HAI rates between the pre-pandemic restricted-visitation period and the pandemic zero-visitation period in a non-COVID tertiary ICU. This single-center retrospective cohort study included patients admitted to the Anesthesiology and Reanimation ICU of the Duzce University Health Practice and Research Center between March 14, 2019, and March 13, 2021. Patients admitted during the pre-pandemic restricted-visitation period were assigned to Group 19 -20, whereas those admitted during the pandemic zero-visitation period were assigned to Group 20-21. Patients with an ICU stay of < 48 hours, infection at admission, or infection developing within the first 48 hours were excluded. The primary outcome was HAI incidence. Secondary outcomes included the standardized infection ratio, cumulative attributable difference, inflammatory markers, and microbiological findings. A total of 933 patients were screened, and 206 patients met the inclusion criteria (Group 20-21, n = 115; Group 19-20, n = 91). In the patient-based analysis, the HAI rate was significantly lower in Group 20-21 than in Group 19-20 (6.1% vs 22.0%, P < .001). Similar findings were observed in the episode-based analysis (10.4% vs 33.0%, P < .001). The time to infection onset was significantly longer in Group 20-21 (P = .003). Procalcitonin, C-reactive protein, white blood cell count, and lactate levels were significantly lower during the zero-visitation period. The standardized infection ratio for ventilator-associated pneumonia was significantly lower in Group 20-21 (P = .02). A marked reduction in the number of Acinetobacter spp. isolates was also observed during the pandemic. A zero-visitation policy in a non-COVID tertiary ICU was associated with lower HAI rates. The consistency of the surveillance indicators, inflammatory markers, and microbiological findings supports the observed association. However, these findings should not be attributed solely to visitor restrictions and should be interpreted in the context of multiple infection control measures implemented during the pandemic. (Copyright © 2026 the Author(s). Published by Wolters Kluwer Health, LLC.) |
| Competing Interests: | The authors have no funding and conflicts of interest to declare. |
| References: | JAMA. 2019 Jul 16;322(3):216-228. (PMID: 31310297) Intensive Care Med. 2017 Apr;43(4):590-591. (PMID: 28028553) Crit Care Sci. 2025 Oct 27;37:e20250099. (PMID: 41172505) Intensive Crit Care Nurs. 2021 Feb;62:102927. (PMID: 32855008) J Infect Prev. 2018 Mar;19(2):87-93. (PMID: 29552099) J Surg Res. 2024 Mar;295:407-413. (PMID: 38070254) Am J Infect Control. 2023 Aug;51(8):900-906. (PMID: 36470450) Intensive Crit Care Nurs. 2022 Feb;68:103140. (PMID: 34750042) Intensive Care Med. 2024 Oct;50(10):1614-1621. (PMID: 39172240) Can J Anaesth. 2021 Oct;68(10):1465-1470. (PMID: 34212307) J Crit Care. 2022 Oct;71:154050. (PMID: 35525226) Pediatr Qual Saf. 2019 Dec 16;4(6):e242. (PMID: 32010868) Am J Med. 2022 Oct;135(10):1158-1167.e3. (PMID: 35472383) Crit Care. 2021 Jun 2;25(1):191. (PMID: 34078445) Can J Anaesth. 2021 Oct;68(10):1474-1484. (PMID: 34195922) Nurs Crit Care. 2024 Nov;29(6):1429-1440. (PMID: 39350566) JAMA Netw Open. 2021 Feb 1;4(2):e210361. (PMID: 33635330) J Infect Public Health. 2015 Nov-Dec;8(6):570-4. (PMID: 26059230) Intensive Care Med. 2022 Jun;48(6):759-761. (PMID: 35554619) Eurasian J Med. 2020 Oct;52(3):254-258. (PMID: 33209077) Am J Infect Control. 2011 Dec;39(10):898-900. (PMID: 21783279) Am J Gastroenterol. 2022 Nov 1;117(11):1874-1876. (PMID: 35862828) Healthcare (Basel). 2025 Jan 31;13(3):. (PMID: 39942477) Am J Infect Control. 2021 Jan;49(1):134-135. (PMID: 33186677) Anaesthesia. 2010 Nov;65(11):1101-5. (PMID: 20840665) Environ Int. 2020 Nov;144:106024. (PMID: 32795751) J Hosp Infect. 2015 Jul;90(3):220-5. (PMID: 25929790) Eur J Clin Invest. 2021 Dec;51(12):e13687. (PMID: 34599600) Int J Nurs Stud. 2021 Sep;121:104000. (PMID: 34242976) Cancer. 2021 Jul 15;127(14):2397-2398. (PMID: 33761133) J Adv Nurs. 2024 Apr;80(4):1355-1369. (PMID: 37897120) Crit Care Med. 1985 Oct;13(10):818-29. (PMID: 3928249) J Infect Dev Ctries. 2022 Feb 28;16(2):320-332. (PMID: 35298428) Am J Infect Control. 2016 Mar 1;44(3):258-62. (PMID: 26940594) Surgery. 2020 Nov;168(5):770-776. (PMID: 32943203) Jt Comm J Qual Patient Saf. 2012 Dec;38(12):560-5. (PMID: 23240264) Intensive Crit Care Nurs. 2024 Feb;80:103534. (PMID: 37783177) Anaesth Crit Care Pain Med. 2019 Dec;38(6):571-572. (PMID: 31785698) Intensive Care Med. 2015 Dec;41(12):2149-60. (PMID: 26499477) J Hosp Infect. 2022 Apr;122:187-193. (PMID: 35093478) Crit Care. 2022 Sep 5;26(1):267. (PMID: 36064613) Germs. 2022 Dec 31;12(4):554-560. (PMID: 38021187) BMC Health Serv Res. 2024 Aug 15;24(1):936. (PMID: 39148067) Intensive Care Med. 2012 Dec;38(12):1930-45. (PMID: 23011531) BMC Infect Dis. 2026 Feb 04;26(1):. (PMID: 41634601) Crit Care. 2021 Sep 25;25(1):347. (PMID: 34563234) J Hosp Infect. 2016 Jun;93(2):121-6. (PMID: 26874935) Crit Care Med. 2018 Jul;46(7):1175-1180. (PMID: 29642108) J Infect Prev. 2025 May;26(3):138-147. (PMID: 40041664) Intensive Crit Care Nurs. 2022 Feb;68:103123. (PMID: 34456111) |
| Contributed Indexing: | Keywords: healthcare-associated infections; infection control; intensive care units; patient visitors |
| Entry Date(s): | Date Created: 20261017 Date Completed: 20261017 Latest Revision: 20261022 |
| Update Code: | 20261022 |
| PubMed Central ID: | PMC13681159 |
| DOI: | 10.1097/MD.0000000000051102 |
| PMID: | 42888540 |
| Βάση Δεδομένων: | MEDLINE |
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