Academic Journal
Hospitalization in adults aged 75 years and older with type 2 diabetes: the role of kidney impairment and glycemic control.
| Τίτλος: | Hospitalization in adults aged 75 years and older with type 2 diabetes: the role of kidney impairment and glycemic control. |
|---|---|
| Συγγραφείς: | Magamba B; Vårdcentralen Falkenberg, Region Halland, Sweden., Jonasson JM; School of Public Health and community medicine, institute of medicine, Sahlgrenska academy, university of Gothenburg, Gothenburg, Sweden., Pettersson L; Research and Innovation Center, Region Halland, Halmstad, Sweden.; Department of Clinical Sciences, Division of Pathology, Lund University, Lund, Sweden., Halling A; Center for Primary Health Care Research, Department of Clinical Sciences, Lund University, Malmö, Sweden., Agvall B; Research and Innovation Center, Region Halland, Halmstad, Sweden. bjorn.agvall@med.lu.se.; Center for Primary Health Care Research, Department of Clinical Sciences, Lund University, Malmö, Sweden. bjorn.agvall@med.lu.se. |
| Πηγή: | BMC geriatrics [BMC Geriatr] 2026 Oct 05; Vol. 26 (1). Date of Electronic Publication: 2026 Oct 05. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: BioMed Central Country of Publication: England NLM ID: 100968548 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2318 (Electronic) Linking ISSN: 14712318 NLM ISO Abbreviation: BMC Geriatr Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: London : BioMed Central, [2001]- |
| Ιατρικοί όροι (MeSH): | Diabetes Mellitus, Type 2*/blood , Diabetes Mellitus, Type 2*/therapy , Diabetes Mellitus, Type 2*/epidemiology , Diabetes Mellitus, Type 2*/complications , Hospitalization*/statistics & numerical data , Hospitalization*/trends , Glycemic Control*/trends , Glycemic Control*/methods, Glycated Hemoglobin/metabolism ; Glycated Hemoglobin/analysis ; Glomerular Filtration Rate/physiology ; Blood Glucose/metabolism ; Humans ; Female ; Aged ; Male ; Aged, 80 and over ; Cohort Studies ; Retrospective Studies |
| Περίληψη: | Background: Older adults aged ≥ 75 years with type 2 diabetes (T2D) experience high healthcare utilization, yet evidence on treatment patterns and outcomes in this age group is limited. Objective: To assess associations between glycemic control, kidney function, and hospitalization among individuals aged ≥ 75 years with T2D. Methods: Individuals aged ≥ 75 years with T2D were identified in 2018 using data from a population‑based healthcare database covering all levels of care in Region Halland. Healthcare utilization, including hospital admissions, hospital days, primary care encounters and mortality, was evaluated during 2019. Inclusion required at least one measurement of glycated hemoglobin (HbA1c) and estimated glomerular filtration rate (eGFR). Kidney function was classified by eGFR ≥ 60; 30-59; <30 mL/min/1.73 m², and HbA1c as < 52, 52-70, or > 70 mmol/mol. Associations with hospital days were analyzed using Poisson regression adjusted for demographic, clinical, and treatment variables. Results: The cohort comprised 1,446 individuals (49% women); 88 patients (6%) died during follow‑up. HbA1c was < 52 mmol/mol in 43%, 52-70 mmol/mol in 45%, and > 70 mmol/mol in 12%. CKD was common, with 56% classified as stage 3 and 10% as stage 4-5. Hospital days were higher among individuals with CKD stage 4-5 (RR 1.93, 95% CI:1.71-2.17) and HbA1c > 70 mmol/mol (RR 1.44, 95% CI:1.28-1.61). Primary care encounters were frequent (physician visits: 4.6 [SD 3.7]; nurse visits: 9.0 [SD 9.3]) and associated with CKD but not with glucose dysregulation. Insulin use was associated with more hospital days, whereas metformin and incretin‑based therapy were associated with fewer. Conclusions: In adults aged ≥ 75 years with T2D, hospitalization burden was substantial and was associated with advanced CKD and poor glycemic control, while primary care encounters were frequent. These findings demonstrate an association between kidney function, glycemic status, and healthcare utilization in older adults with T2D. (© 2026. The Author(s).) |
| Competing Interests: | Declarations. Ethics approval: Ethics approval for this study was granted by the Swedish Ethical Review Board at the Gothenburg Department of Medicine (registration number 2020–05769). All methods and procedures employed in this research strictly adhered to relevant research guidelines and regulations, including the principles outlined in the Declaration of Helsinki. Consent form: Due to the retrospective nature of this observational cohort study, the requirement for informed consent was waived, in accordance with the approvals provided by the Swedish Ethical Review Board. Disclosure statement: No potential conflict of interest was reported by the authors. Competing interests: The authors declare no competing interests. |
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| Contributed Indexing: | Keywords: Aged; Chronic kidney disease; Glycosylated hemoglobin A; Hospitalization; Primary care; Type 2 diabetes |
| Substance Nomenclature: | 0 (Glycated Hemoglobin) 0 (Blood Glucose) |
| Entry Date(s): | Date Created: 20261006 Date Completed: 20261006 Latest Revision: 20261008 |
| Update Code: | 20261008 |
| PubMed Central ID: | PMC13640178 |
| DOI: | 10.1186/s12877-026-08386-7 |
| PMID: | 42834370 |
| Βάση Δεδομένων: | MEDLINE |
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