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Genomic features of mecA-harboring Staphylococcus epidermidis infecting an illegally traded rufous-bellied thrush (T. rufiventris).

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Genomic features of mecA-harboring Staphylococcus epidermidis infecting an illegally traded rufous-bellied thrush (T. rufiventris).
Συγγραφείς: Pompeu BAA; Departamento de Medicina Veterinária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, Av. Prof. Orlando Marques de Paiva, 87 - Butantã, São Paulo, 05508-270, Brazil., Dos Santos GS; Departamento de Medicina Veterinária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, Av. Prof. Orlando Marques de Paiva, 87 - Butantã, São Paulo, 05508-270, Brazil. gabriel.siqueira.santos@alumni.usp.br., Zwarg T; Divisão da Fauna Silvestre, Prefeitura Municipal de São Paulo, Estrada de Perus, 300, São Paulo, 05276-11, Brazil., Frediani MH; Divisão da Fauna Silvestre, Prefeitura Municipal de São Paulo, Estrada de Perus, 300, São Paulo, 05276-11, Brazil., Haisi A; Instituto de Biotecnologia, Universidade Estadual Paulista 'Julio de Mesquita Filho', Alameda das Tecomarias, Chácara Capão Bonito, Botucatu, 18607-440, Brazil., Araújo JP Jr; Instituto de Biotecnologia, Universidade Estadual Paulista 'Julio de Mesquita Filho', Alameda das Tecomarias, Chácara Capão Bonito, Botucatu, 18607-440, Brazil., Neto JSF; Departamento de Medicina Veterinária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, Av. Prof. Orlando Marques de Paiva, 87 - Butantã, São Paulo, 05508-270, Brazil., Heinemann MB; Departamento de Medicina Veterinária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, Av. Prof. Orlando Marques de Paiva, 87 - Butantã, São Paulo, 05508-270, Brazil.
Πηγή: Veterinary research communications [Vet Res Commun] 2026 Sep 28; Vol. 50 (6). Date of Electronic Publication: 2026 Sep 28.
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Springer Country of Publication: Switzerland NLM ID: 8100520 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7446 (Electronic) Linking ISSN: 01657380 NLM ISO Abbreviation: Vet Res Commun Subsets: MEDLINE
Imprint Name(s): Publication: [Cham] : Springer
Original Publication: [Amsterdam] : Elsevier, 1980-
Ιατρικοί όροι (MeSH): Staphylococcus epidermidis*/genetics , Staphylococcus epidermidis*/drug effects , Staphylococcus epidermidis*/isolation & purification , Bacterial Proteins*/genetics , Staphylococcal Infections*/veterinary , Staphylococcal Infections*/microbiology , Drug Resistance, Multiple, Bacterial*/genetics , Penicillin-Binding Proteins*/genetics , Bird Diseases*/microbiology, Anti-Bacterial Agents/pharmacology ; Methicillin Resistance/genetics ; Microbial Sensitivity Tests/veterinary ; Animals ; Birds ; Genome, Bacterial
Περίληψη: Staphylococcus epidermidis is an opportunistic bacterium frequently involved in healthcare-associated infections and has become increasingly relevant in One Health when associated with methicillin resistance profile. Despite its significance in human medicine, the circulation of S. epidermidis in wildlife still poorly reported. In this study, we communicate the isolation and genomic characterization of a multidrug-resistant S. epidermidis Sequence Type 280 isolated from a skin lesion in an illegally traded wild rufous-bellied thrush (Turdus rufiventris). Antimicrobial susceptibility tests and genome sequencing revealed extensive multidrug resistance, including resistance to methicillin, related to the presence of antimicrobial resistance (mecA; blaZ; aadD; aac(6') - aph(2''); fosB; erm(C) and rpoB (D471E/I527M)). This finding provides compelling evidence for the global dissemination and ecological plasticity of this clone. Ultimately, the detection of methicillin-resistant S. epidermidis in a wild bird highlights the potential for urban environments to harbor and disseminate antimicrobial-resistant bacteria, highlighting the need to incorporate wildlife monitoring into One Health surveillance models.
(© 2026. The Author(s).)
Competing Interests: Declarations. Conflict of interest: The authors declare no conflict of interest.
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Grant Information: 24/17243-8 Fundação de Amparo à Pesquisa do Estado de São Paulo; 302899/2022 Conselho Nacional de Desenvolvimento Científico e Tecnológico; 310462/2021 Conselho Nacional de Desenvolvimento Científico e Tecnológico
Contributed Indexing: Keywords: Staphylococcus epidermidis; Antibiotic resistance; Methicillin resistant; One Health
Substance Nomenclature: 0 (Bacterial Proteins)
0 (Anti-Bacterial Agents)
0 (MecA protein, Staphylococcus epidermidis)
0 (Penicillin-Binding Proteins)
Entry Date(s): Date Created: 20260928 Date Completed: 20260928 Latest Revision: 20261024
Update Code: 20261024
PubMed Central ID: PMC13619737
DOI: 10.1007/s11259-026-11540-6
PMID: 42804045
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:1573-7446
DOI:10.1007/s11259-026-11540-6