Academic Journal
Biomonitoring of urban ultrafine particle exposure and associated health effects.
| Τίτλος: | Biomonitoring of urban ultrafine particle exposure and associated health effects. |
|---|---|
| Συγγραφείς: | Fireman EM; Department Environmental Occupational Health, Gray Faculty Medical Health Science, Tel Aviv, Israel., Fireman Klein E; Pulmonary Division Carmel Medical Center, Rappaport Faculty of Sciences, Technion Institute Technology, Haifa, Israel., Dabach M; Pulmonary Department, Ichilov Hospital Tel Aviv University, Tel Aviv, Israel., Hardak E; Pulmonary Unit, Bnai Zion Medical Center Rappaport Faculty of Sciences, Technion Institute Technology, Haifa, Israel. |
| Πηγή: | International journal of public health [Int J Public Health] 2026 Sep 01; Vol. 71, pp. 1609855. Date of Electronic Publication: 2026 Sep 01 (Print Publication: 2026). |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101304551 Publication Model: eCollection Cited Medium: Internet ISSN: 1661-8564 (Electronic) Linking ISSN: 16618556 NLM ISO Abbreviation: Int J Public Health Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2021- : Lausanne, Switzerland : Frontiers Media S.A. Original Publication: Basel : Birkhäuser |
| Ιατρικοί όροι (MeSH): | Particulate Matter*/analysis , Particulate Matter*/adverse effects , Environmental Exposure*/adverse effects , Environmental Exposure*/analysis , Biological Monitoring*/methods , Air Pollutants*/analysis , Air Pollutants*/adverse effects , Air Pollution*/adverse effects , Air Pollution*/analysis, Saliva/chemistry ; Environmental Monitoring/methods ; Humans ; Female ; Male ; Adult ; Middle Aged ; Israel ; Particle Size ; Spirometry ; Breath Tests ; Urban Population ; Surveys and Questionnaires |
| Περίληψη: | Objective: To assess the health impact of industrial and urban air pollution in the Haifa Bay area using biological monitoring of micro- and ultrafine particles (UFPs), and to examine their associations with functional, inflammatory, and clinical outcomes. Methods: The study included 99 hospital staff members: 50 from Bnai Zion Medical Center in the Haifa Bay area and 49 from Tel Aviv Medical Center as controls. Participants underwent spirometry, fractional exhaled nitric oxide (FeNO) measurement, exhaled breath condensate (EBC) and saliva collection, and completed a health questionnaire. Assessments were repeated after 1 year. Latent class analysis (LCA) was used to identify homogeneous subgroups based on biological and clinical parameters. Results: LCA identified a cluster characterized by higher body mass index, increased UFP concentrations in EBC, and elevated salivary LDH-calcium levels. This cluster consisted predominantly of participants from Haifa and showed higher salivary lymphocyte counts. Participants in this subgroup also reported more frequent respiratory symptoms, including cough, sputum production, and atopic complaints. Conclusion: Biological monitoring of nanosized particles may provide early indicators of adverse health effects associated with urban-industrial air pollution exposure. (Copyright © 2026 Fireman, Fireman Klein, Dabach and Hardak.) |
| Competing Interests: | The authors declare that they do not have any conflicts of interest. |
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| Contributed Indexing: | Keywords: bio-monitoring and evaluation; human; inflammation; ultra-fine particles (UFP); urban areas |
| Substance Nomenclature: | 0 (Particulate Matter) 0 (Air Pollutants) |
| Entry Date(s): | Date Created: 20260916 Date Completed: 20260916 Latest Revision: 20260917 |
| Update Code: | 20260917 |
| PubMed Central ID: | PMC13575386 |
| DOI: | 10.3389/ijph.2026.1609855 |
| PMID: | 42746163 |
| Βάση Δεδομένων: | MEDLINE |
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