Academic Journal
Synergistic magneto-enzymatic propulsion enables multimodal nanomotor swarms.
| Τίτλος: | Synergistic magneto-enzymatic propulsion enables multimodal nanomotor swarms. |
|---|---|
| Συγγραφείς: | Bakenecker AC; Institute for Bioengineering of Catalonia (IBEC), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. anna.bakenecker@tu-darmstadt.de.; Medical Engineering, Department of Electrical Engineering and Information Technology, Technical University of Darmstadt, Darmstadt, Germany. anna.bakenecker@tu-darmstadt.de., Arqué X; Institute for Bioengineering of Catalonia (IBEC), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. xavier.arque@espci.fr.; Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain. xavier.arque@espci.fr.; Gulliver UMR CNRS 7083, ESPCI ParisTech, PSL Research University, Paris, France. xavier.arque@espci.fr., Peetroons X; Institute for Bioengineering of Catalonia (IBEC), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Soto Rodriguez PED; Aix-Marseille University, CNRS, CEA, BIAM, Saint-Paul-lez-Durance, France.; Instituto de estudios avanzados IUDEA, Departamento de Física, Universidad de La Laguna C/Astrofísico Francisco Sánchez, Tenerife, Spain., Prévéral S; Aix-Marseille University, CNRS, CEA, BIAM, Saint-Paul-lez-Durance, France., Faivre D; Aix-Marseille University, CNRS, CEA, BIAM, Saint-Paul-lez-Durance, France.; Department of Physics, Faculty of Science and Technology, University of Latvia, Riga, Latvia., Sánchez S; Institute for Bioengineering of Catalonia (IBEC), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. ssanchez@ibecbarcelona.eu.; Catalan Institute for Research and Advanced Studies (ICREA), Barcelona, Spain. ssanchez@ibecbarcelona.eu. |
| Πηγή: | Nature communications [Nat Commun] 2026 Aug 11; Vol. 17 (1). Date of Electronic Publication: 2026 Aug 11. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: [London] : Nature Pub. Group |
| Ιατρικοί όροι (MeSH): | Urease*/metabolism , Urease*/chemistry , Magnetosomes*/chemistry , Magnetosomes*/metabolism, Magnetic Fields ; Catalysis ; Magnetospirillum ; Magnetics |
| Περίληψη: | Enzymatic nanomotors self-propel by converting free molecular energy from chemical reactions. While initially used mainly as individual particles, these systems are increasingly implemented as swarms, where collective effects enable adaptable navigation in complex environments, broader coverage and enhanced local agent concentration. However, most studies have focused on planar swarming, and collective systems that combine magnetic navigation with enzyme-powered motion remain largely underexplored. Here, as a mechanistic proof-of-principle, we introduce urease-powered nanomotors based on bioproduced magnetosomes that operate in two sequential collective modes: (i) magnetic localization of the ensemble and (ii) catalysis-triggered, interface-dependent expansion of that localized cloud. We investigate this catalytic collective phenomenon under varying conditions, including particle and substrate concentrations, media viscosity, and confinement, and devote particular attention to distinguishing urea-driven buoyant accumulation from catalysis-dependent interfacial spreading using combined top/side-view imaging and inactive particle controls. Finally, we examine the swarm under a magnetic field gradient to concentrate it in a target area and then trigger catalytic expansion. In confined environments, where the free-interface expansion is suppressed, magnetic localization and local enrichment remain operative. Rather than targeting a specific immediate application, this work establishes a two step collective strategy, clarifies the mechanism underlying a distinct catalytic swarm mode, and defines the physical conditions that may support future environmental and biomedical implementations of multimodal nanomotor swarms. (© 2026. The Author(s).) |
| Competing Interests: | Competing interests: There are no conflicts to declare. |
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| Grant Information: | 866348 EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council); LOEWE-Start Hessisches Ministerium für Wissenschaft und Kunst (Hessen State Ministry of Higher Education, Research and the Arts) |
| Substance Nomenclature: | EC 3.5.1.5 (Urease) |
| Entry Date(s): | Date Created: 20260910 Date Completed: 20260910 Latest Revision: 20260914 |
| Update Code: | 20260914 |
| PubMed Central ID: | PMC13558676 |
| DOI: | 10.1038/s41467-026-76053-x |
| PMID: | 42717205 |
| Βάση Δεδομένων: | MEDLINE |
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