Academic Journal

Development and Psychometric Validation of the Human Papillomavirus Prevention Health Literacy Scale for College Students in Taiwan.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Development and Psychometric Validation of the Human Papillomavirus Prevention Health Literacy Scale for College Students in Taiwan.
Συγγραφείς: Lai CY; Department of Nursing, Central Taiwan University of Science and Technology, Taichung, Taiwan., Yang SC; Department of Nursing, Central Taiwan University of Science and Technology, Taichung, Taiwan., Liu CY; Institute of Community Health Care, College of Nursing, National Yang Ming Chiao Tung University, Taipei, Taiwan., Lin HR; School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan., Liao YM; Institute of Clinical Nursing, College of Nursing, National Yang Ming Chiao Tung University, Taipei, Taiwan., Lee TY; School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.
Πηγή: The journal of nursing research : JNR [J Nurs Res] 2026 Oct 01; Vol. 34 (5), pp. e476. Date of Electronic Publication: 2026 Oct 01.
Τύπος έκδοσης: Journal Article; Validation Study
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Lippincott Williams & Wilkins Country of Publication: China (Republic : 1949- ) NLM ID: 101128757 Publication Model: Electronic Cited Medium: Internet ISSN: 1948-965X (Electronic) Linking ISSN: 16823141 NLM ISO Abbreviation: J Nurs Res Subsets: MEDLINE
Imprint Name(s): Publication: March 2009- : Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: Taipei, Taiwan, ROC : Taiwan Nurses Association, [2001-
Ιατρικοί όροι (MeSH): Psychometrics*/standards , Psychometrics*/instrumentation , Psychometrics*/methods , Papillomavirus Infections*/prevention & control , Papillomavirus Infections*/psychology , Students*/psychology , Students*/statistics & numerical data , Health Literacy*/standards , Health Literacy*/statistics & numerical data , Health Literacy*/methods, Universities/organization & administration ; Universities/statistics & numerical data ; Humans ; Taiwan ; Female ; Reproducibility of Results ; Cross-Sectional Studies ; Surveys and Questionnaires ; Male ; Adult ; Young Adult ; Human Papillomavirus Viruses
Περίληψη: Background: Human papillomavirus (HPV) is a common sexually transmitted virus associated with several types of cancer. Because college students are a high-risk group, understanding their health literacy with regard to HPV prevention is critical. However, no suitable measurement tools are currently available for this purpose.
Purpose: In this study, an HPV Prevention Health Literacy Scale (HPV-HLS) was developed, and its reliability and validity were assessed.
Methods: A cross-sectional design was used, and the developed scale was validated on a sample of 372 college students from two universities in northern Taiwan and one university in central Taiwan. The initial scale comprised 49 items, developed from qualitative interviews and a literature review. After content validity assessment and item analysis, the scale was refined to 37 items. Exploratory factor analysis (EFA) was conducted with 150 participants, followed by confirmatory factor analysis (CFA) with 222 participants. Concurrent validity and internal consistency reliability were assessed. Data were collected from November 2021 to December 2022.
Results: The results of the EFA revealed a two-factor model accounted for 60.30% of the total variation, and those of the CFA demonstrated favorable goodness-of-fit indices (GFI = .81, CFI = .92, TLI = .91, RMSEA = .07, and SRMR = .02). Moreover, the average variance extracted (AVE) for the two factors were .56 and .64, respectively, with corresponding composite reliability (CR) values of .96 and .93, indicating excellent convergent validity. Notably, the AVE surpassed the squared product-moment correlation of the corresponding factors, affirming good discriminant validity. The final iteration of the HPV-HLS comprised 21 items with two subscales: comprehension and evaluation of general information and seeking information from health care professionals. Concurrent validity was found between the proposed scale and the Mandarin Multidimensional Health Literacy Questionnaire ( r = .68, p < .001). The HPV-HLS demonstrated good internal consistency (Cronbach's α = .959).
Conclusions/implications for Future Practice: After rigorous psychometric testing, the newly developed HPV-HLS demonstrated excellent reliability and validity, establishing it as an objective tool for evaluating HPV prevention health literacy among college students. This HPV-HLS may be used by health care providers and educators to assess health literacy and evaluate the effectiveness of clinical interventions to prevent HPV infection.
(Copyright © 2026 The Author(s). Published by Wolters Kluwer Health, LLC. on behalf of the Taiwan Nurses Association.)
Competing Interests: The authors declare no conflicts of interest.
References: J Clin Nurs. 2025 Mar;34(3):795-804. (PMID: 39128973)
J Nurs Res. 2024 Oct 01;32(5):e347. (PMID: 39177487)
Sci Rep. 2025 Jul 1;15(1):21048. (PMID: 40593150)
Hum Vaccin Immunother. 2021 Aug 3;17(8):2736-2747. (PMID: 33787459)
J Nurs Res. 2024 Aug 01;32(4):e337. (PMID: 39037391)
J Behav Med. 2024 Apr;47(2):334-341. (PMID: 38180576)
J Pediatr Nurs. 2024 May-Jun;76:124-131. (PMID: 38382187)
J Am Coll Health. 2013;61(1):28-35. (PMID: 23305542)
J Community Health. 2018 Dec;43(6):1192-1200. (PMID: 29922992)
BMC Public Health. 2013 Oct 10;13:948. (PMID: 24112855)
Cult Health Sex. 2024 Jul;26(7):936-951. (PMID: 37950430)
Public Health. 2020 May;182:125-130. (PMID: 32272289)
Fam Med. 1993 Jun;25(6):391-5. (PMID: 8349060)
Res Nurs Health. 2007 Aug;30(4):459-67. (PMID: 17654487)
Healthcare (Basel). 2021 Oct 18;9(10):. (PMID: 34683071)
J Multidiscip Healthc. 2024 Jan 30;17:409-418. (PMID: 38314013)
Sex Transm Dis. 2021 Apr 1;48(4):278-284. (PMID: 33492104)
Front Public Health. 2022 Aug 24;10:946889. (PMID: 36091498)
J Adv Nurs. 2025 Apr;81(4):1902-1913. (PMID: 39180745)
Sci Rep. 2023 May 10;13(1):7633. (PMID: 37165210)
Vaccine. 2012 Nov 20;30 Suppl 5:F12-23. (PMID: 23199955)
J Gen Intern Med. 1995 Oct;10(10):537-41. (PMID: 8576769)
Contributed Indexing: Keywords: HPV; college students; health literacy; human papillomavirus; scale
Entry Date(s): Date Created: 20260828 Date Completed: 20260923 Latest Revision: 20260926
Update Code: 20260926
PubMed Central ID: PMC13608273
DOI: 10.1097/jnr.0000000000000767
PMID: 42663177
Βάση Δεδομένων: MEDLINE
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  Data: Development and Psychometric Validation of the Human Papillomavirus Prevention Health Literacy Scale for College Students in Taiwan.
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  Data: &lt;searchLink fieldCode=&quot;AU&quot; term=&quot;%22Lai+CY%22&quot;&gt;Lai CY&lt;/searchLink&gt;; Department of Nursing, Central Taiwan University of Science and Technology, Taichung, Taiwan.&lt;br /&gt;&lt;searchLink fieldCode=&quot;AU&quot; term=&quot;%22Yang+SC%22&quot;&gt;Yang SC&lt;/searchLink&gt;; Department of Nursing, Central Taiwan University of Science and Technology, Taichung, Taiwan.&lt;br /&gt;&lt;searchLink fieldCode=&quot;AU&quot; term=&quot;%22Liu+CY%22&quot;&gt;Liu CY&lt;/searchLink&gt;; Institute of Community Health Care, College of Nursing, National Yang Ming Chiao Tung University, Taipei, Taiwan.&lt;br /&gt;&lt;searchLink fieldCode=&quot;AU&quot; term=&quot;%22Lin+HR%22&quot;&gt;Lin HR&lt;/searchLink&gt;; School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.&lt;br /&gt;&lt;searchLink fieldCode=&quot;AU&quot; term=&quot;%22Liao+YM%22&quot;&gt;Liao YM&lt;/searchLink&gt;; Institute of Clinical Nursing, College of Nursing, National Yang Ming Chiao Tung University, Taipei, Taiwan.&lt;br /&gt;&lt;searchLink fieldCode=&quot;AU&quot; term=&quot;%22Lee+TY%22&quot;&gt;Lee TY&lt;/searchLink&gt;; School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.
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– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Human papillomavirus (HPV) is a common sexually transmitted virus associated with several types of cancer. Because college students are a high-risk group, understanding their health literacy with regard to HPV prevention is critical. However, no suitable measurement tools are currently available for this purpose.&lt;br /&gt;Purpose: In this study, an HPV Prevention Health Literacy Scale (HPV-HLS) was developed, and its reliability and validity were assessed.&lt;br /&gt;Methods: A cross-sectional design was used, and the developed scale was validated on a sample of 372 college students from two universities in northern Taiwan and one university in central Taiwan. The initial scale comprised 49 items, developed from qualitative interviews and a literature review. After content validity assessment and item analysis, the scale was refined to 37 items. Exploratory factor analysis (EFA) was conducted with 150 participants, followed by confirmatory factor analysis (CFA) with 222 participants. Concurrent validity and internal consistency reliability were assessed. Data were collected from November 2021 to December 2022.&lt;br /&gt;Results: The results of the EFA revealed a two-factor model accounted for 60.30% of the total variation, and those of the CFA demonstrated favorable goodness-of-fit indices (GFI = .81, CFI = .92, TLI = .91, RMSEA = .07, and SRMR = .02). Moreover, the average variance extracted (AVE) for the two factors were .56 and .64, respectively, with corresponding composite reliability (CR) values of .96 and .93, indicating excellent convergent validity. Notably, the AVE surpassed the squared product-moment correlation of the corresponding factors, affirming good discriminant validity. The final iteration of the HPV-HLS comprised 21 items with two subscales: comprehension and evaluation of general information and seeking information from health care professionals. Concurrent validity was found between the proposed scale and the Mandarin Multidimensional Health Literacy Questionnaire ( r = .68, p &amp;lt; .001). The HPV-HLS demonstrated good internal consistency (Cronbach&#39;s α = .959).&lt;br /&gt;Conclusions/implications for Future Practice: After rigorous psychometric testing, the newly developed HPV-HLS demonstrated excellent reliability and validity, establishing it as an objective tool for evaluating HPV prevention health literacy among college students. This HPV-HLS may be used by health care providers and educators to assess health literacy and evaluate the effectiveness of clinical interventions to prevent HPV infection.&lt;br /&gt; (Copyright &#169; 2026 The Author(s). Published by Wolters Kluwer Health, LLC. on behalf of the Taiwan Nurses Association.)
– Name: Abstract
  Label: Competing Interests
  Group: Ab
  Data: The authors declare no conflicts of interest.
– Name: Ref
  Label: References
  Group: RefInfo
  Data: J Clin Nurs. 2025 Mar;34(3):795-804. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2239128973%22&quot;&gt;39128973)&lt;/searchLink&gt;&lt;br /&gt;J Nurs Res. 2024 Oct 01;32(5):e347. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2239177487%22&quot;&gt;39177487)&lt;/searchLink&gt;&lt;br /&gt;Sci Rep. 2025 Jul 1;15(1):21048. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2240593150%22&quot;&gt;40593150)&lt;/searchLink&gt;&lt;br /&gt;Hum Vaccin Immunother. 2021 Aug 3;17(8):2736-2747. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2233787459%22&quot;&gt;33787459)&lt;/searchLink&gt;&lt;br /&gt;J Nurs Res. 2024 Aug 01;32(4):e337. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2239037391%22&quot;&gt;39037391)&lt;/searchLink&gt;&lt;br /&gt;J Behav Med. 2024 Apr;47(2):334-341. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2238180576%22&quot;&gt;38180576)&lt;/searchLink&gt;&lt;br /&gt;J Pediatr Nurs. 2024 May-Jun;76:124-131. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2238382187%22&quot;&gt;38382187)&lt;/searchLink&gt;&lt;br /&gt;J Am Coll Health. 2013;61(1):28-35. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2223305542%22&quot;&gt;23305542)&lt;/searchLink&gt;&lt;br /&gt;J Community Health. 2018 Dec;43(6):1192-1200. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2229922992%22&quot;&gt;29922992)&lt;/searchLink&gt;&lt;br /&gt;BMC Public Health. 2013 Oct 10;13:948. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2224112855%22&quot;&gt;24112855)&lt;/searchLink&gt;&lt;br /&gt;Cult Health Sex. 2024 Jul;26(7):936-951. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2237950430%22&quot;&gt;37950430)&lt;/searchLink&gt;&lt;br /&gt;Public Health. 2020 May;182:125-130. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2232272289%22&quot;&gt;32272289)&lt;/searchLink&gt;&lt;br /&gt;Fam Med. 1993 Jun;25(6):391-5. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%228349060%22&quot;&gt;8349060)&lt;/searchLink&gt;&lt;br /&gt;Res Nurs Health. 2007 Aug;30(4):459-67. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2217654487%22&quot;&gt;17654487)&lt;/searchLink&gt;&lt;br /&gt;Healthcare (Basel). 2021 Oct 18;9(10):. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2234683071%22&quot;&gt;34683071)&lt;/searchLink&gt;&lt;br /&gt;J Multidiscip Healthc. 2024 Jan 30;17:409-418. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2238314013%22&quot;&gt;38314013)&lt;/searchLink&gt;&lt;br /&gt;Sex Transm Dis. 2021 Apr 1;48(4):278-284. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2233492104%22&quot;&gt;33492104)&lt;/searchLink&gt;&lt;br /&gt;Front Public Health. 2022 Aug 24;10:946889. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2236091498%22&quot;&gt;36091498)&lt;/searchLink&gt;&lt;br /&gt;J Adv Nurs. 2025 Apr;81(4):1902-1913. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2239180745%22&quot;&gt;39180745)&lt;/searchLink&gt;&lt;br /&gt;Sci Rep. 2023 May 10;13(1):7633. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2237165210%22&quot;&gt;37165210)&lt;/searchLink&gt;&lt;br /&gt;Vaccine. 2012 Nov 20;30 Suppl 5:F12-23. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2223199955%22&quot;&gt;23199955)&lt;/searchLink&gt;&lt;br /&gt;J Gen Intern Med. 1995 Oct;10(10):537-41. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%228576769%22&quot;&gt;8576769)&lt;/searchLink&gt;
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  Data: &lt;i&gt;Keywords: &lt;/i&gt;HPV; college students; health literacy; human papillomavirus; scale
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    Identifiers:
      – Type: doi
        Value: 10.1097/jnr.0000000000000767
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: e476
    Subjects:
      – SubjectFull: Universities organization & administration
        Type: general
      – SubjectFull: Universities statistics & numerical data
        Type: general
      – SubjectFull: Humans
        Type: general
      – SubjectFull: Taiwan
        Type: general
      – SubjectFull: Female
        Type: general
      – SubjectFull: Reproducibility of Results
        Type: general
      – SubjectFull: Cross-Sectional Studies
        Type: general
      – SubjectFull: Surveys and Questionnaires
        Type: general
      – SubjectFull: Male
        Type: general
      – SubjectFull: Adult
        Type: general
      – SubjectFull: Young Adult
        Type: general
      – SubjectFull: Human Papillomavirus Viruses
        Type: general
      – SubjectFull: Psychometrics standards
        Type: general
      – SubjectFull: Psychometrics instrumentation
        Type: general
      – SubjectFull: Psychometrics methods
        Type: general
      – SubjectFull: Papillomavirus Infections prevention & control
        Type: general
      – SubjectFull: Papillomavirus Infections psychology
        Type: general
      – SubjectFull: Students psychology
        Type: general
      – SubjectFull: Students statistics & numerical data
        Type: general
      – SubjectFull: Health Literacy standards
        Type: general
      – SubjectFull: Health Literacy statistics & numerical data
        Type: general
      – SubjectFull: Health Literacy methods
        Type: general
    Titles:
      – TitleFull: Development and Psychometric Validation of the Human Papillomavirus Prevention Health Literacy Scale for College Students in Taiwan.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Lai CY
      – PersonEntity:
          Name:
            NameFull: Yang SC
      – PersonEntity:
          Name:
            NameFull: Liu CY
      – PersonEntity:
          Name:
            NameFull: Lin HR
      – PersonEntity:
          Name:
            NameFull: Liao YM
      – PersonEntity:
          Name:
            NameFull: Lee TY
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 10
              Text: 2026 Oct 01
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1948-965X
          Numbering:
            – Type: volume
              Value: 34
            – Type: issue
              Value: 5
          Titles:
            – TitleFull: The journal of nursing research : JNR
              Type: main
ResultId 1