Academic Journal
Development and Psychometric Validation of the Human Papillomavirus Prevention Health Literacy Scale for College Students in Taiwan.
| Τίτλος: | Development and Psychometric Validation of the Human Papillomavirus Prevention Health Literacy Scale for College Students in Taiwan. |
|---|---|
| Συγγραφείς: | Lai CY; Department of Nursing, Central Taiwan University of Science and Technology, Taichung, Taiwan., Yang SC; Department of Nursing, Central Taiwan University of Science and Technology, Taichung, Taiwan., Liu CY; Institute of Community Health Care, College of Nursing, National Yang Ming Chiao Tung University, Taipei, Taiwan., Lin HR; School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan., Liao YM; Institute of Clinical Nursing, College of Nursing, National Yang Ming Chiao Tung University, Taipei, Taiwan., Lee TY; School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan. |
| Πηγή: | The journal of nursing research : JNR [J Nurs Res] 2026 Oct 01; Vol. 34 (5), pp. e476. Date of Electronic Publication: 2026 Oct 01. |
| Τύπος έκδοσης: | Journal Article; Validation Study |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Lippincott Williams & Wilkins Country of Publication: China (Republic : 1949- ) NLM ID: 101128757 Publication Model: Electronic Cited Medium: Internet ISSN: 1948-965X (Electronic) Linking ISSN: 16823141 NLM ISO Abbreviation: J Nurs Res Subsets: MEDLINE |
| Imprint Name(s): | Publication: March 2009- : Hagerstown, MD : Lippincott Williams & Wilkins Original Publication: Taipei, Taiwan, ROC : Taiwan Nurses Association, [2001- |
| Ιατρικοί όροι (MeSH): | Psychometrics*/standards , Psychometrics*/instrumentation , Psychometrics*/methods , Papillomavirus Infections*/prevention & control , Papillomavirus Infections*/psychology , Students*/psychology , Students*/statistics & numerical data , Health Literacy*/standards , Health Literacy*/statistics & numerical data , Health Literacy*/methods, Universities/organization & administration ; Universities/statistics & numerical data ; Humans ; Taiwan ; Female ; Reproducibility of Results ; Cross-Sectional Studies ; Surveys and Questionnaires ; Male ; Adult ; Young Adult ; Human Papillomavirus Viruses |
| Περίληψη: | Background: Human papillomavirus (HPV) is a common sexually transmitted virus associated with several types of cancer. Because college students are a high-risk group, understanding their health literacy with regard to HPV prevention is critical. However, no suitable measurement tools are currently available for this purpose. Purpose: In this study, an HPV Prevention Health Literacy Scale (HPV-HLS) was developed, and its reliability and validity were assessed. Methods: A cross-sectional design was used, and the developed scale was validated on a sample of 372 college students from two universities in northern Taiwan and one university in central Taiwan. The initial scale comprised 49 items, developed from qualitative interviews and a literature review. After content validity assessment and item analysis, the scale was refined to 37 items. Exploratory factor analysis (EFA) was conducted with 150 participants, followed by confirmatory factor analysis (CFA) with 222 participants. Concurrent validity and internal consistency reliability were assessed. Data were collected from November 2021 to December 2022. Results: The results of the EFA revealed a two-factor model accounted for 60.30% of the total variation, and those of the CFA demonstrated favorable goodness-of-fit indices (GFI = .81, CFI = .92, TLI = .91, RMSEA = .07, and SRMR = .02). Moreover, the average variance extracted (AVE) for the two factors were .56 and .64, respectively, with corresponding composite reliability (CR) values of .96 and .93, indicating excellent convergent validity. Notably, the AVE surpassed the squared product-moment correlation of the corresponding factors, affirming good discriminant validity. The final iteration of the HPV-HLS comprised 21 items with two subscales: comprehension and evaluation of general information and seeking information from health care professionals. Concurrent validity was found between the proposed scale and the Mandarin Multidimensional Health Literacy Questionnaire ( r = .68, p < .001). The HPV-HLS demonstrated good internal consistency (Cronbach's α = .959). Conclusions/implications for Future Practice: After rigorous psychometric testing, the newly developed HPV-HLS demonstrated excellent reliability and validity, establishing it as an objective tool for evaluating HPV prevention health literacy among college students. This HPV-HLS may be used by health care providers and educators to assess health literacy and evaluate the effectiveness of clinical interventions to prevent HPV infection. (Copyright © 2026 The Author(s). Published by Wolters Kluwer Health, LLC. on behalf of the Taiwan Nurses Association.) |
| Competing Interests: | The authors declare no conflicts of interest. |
| References: | J Clin Nurs. 2025 Mar;34(3):795-804. (PMID: 39128973) J Nurs Res. 2024 Oct 01;32(5):e347. (PMID: 39177487) Sci Rep. 2025 Jul 1;15(1):21048. (PMID: 40593150) Hum Vaccin Immunother. 2021 Aug 3;17(8):2736-2747. (PMID: 33787459) J Nurs Res. 2024 Aug 01;32(4):e337. (PMID: 39037391) J Behav Med. 2024 Apr;47(2):334-341. (PMID: 38180576) J Pediatr Nurs. 2024 May-Jun;76:124-131. (PMID: 38382187) J Am Coll Health. 2013;61(1):28-35. (PMID: 23305542) J Community Health. 2018 Dec;43(6):1192-1200. (PMID: 29922992) BMC Public Health. 2013 Oct 10;13:948. (PMID: 24112855) Cult Health Sex. 2024 Jul;26(7):936-951. (PMID: 37950430) Public Health. 2020 May;182:125-130. (PMID: 32272289) Fam Med. 1993 Jun;25(6):391-5. (PMID: 8349060) Res Nurs Health. 2007 Aug;30(4):459-67. (PMID: 17654487) Healthcare (Basel). 2021 Oct 18;9(10):. (PMID: 34683071) J Multidiscip Healthc. 2024 Jan 30;17:409-418. (PMID: 38314013) Sex Transm Dis. 2021 Apr 1;48(4):278-284. (PMID: 33492104) Front Public Health. 2022 Aug 24;10:946889. (PMID: 36091498) J Adv Nurs. 2025 Apr;81(4):1902-1913. (PMID: 39180745) Sci Rep. 2023 May 10;13(1):7633. (PMID: 37165210) Vaccine. 2012 Nov 20;30 Suppl 5:F12-23. (PMID: 23199955) J Gen Intern Med. 1995 Oct;10(10):537-41. (PMID: 8576769) |
| Contributed Indexing: | Keywords: HPV; college students; health literacy; human papillomavirus; scale |
| Entry Date(s): | Date Created: 20260828 Date Completed: 20260923 Latest Revision: 20260926 |
| Update Code: | 20260926 |
| PubMed Central ID: | PMC13608273 |
| DOI: | 10.1097/jnr.0000000000000767 |
| PMID: | 42663177 |
| Βάση Δεδομένων: | MEDLINE |
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| Items | – Name: Title Label: Title Group: Ti Data: Development and Psychometric Validation of the Human Papillomavirus Prevention Health Literacy Scale for College Students in Taiwan. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Lai+CY%22">Lai CY</searchLink>; Department of Nursing, Central Taiwan University of Science and Technology, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yang+SC%22">Yang SC</searchLink>; Department of Nursing, Central Taiwan University of Science and Technology, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+CY%22">Liu CY</searchLink>; Institute of Community Health Care, College of Nursing, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+HR%22">Lin HR</searchLink>; School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liao+YM%22">Liao YM</searchLink>; Institute of Clinical Nursing, College of Nursing, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+TY%22">Lee TY</searchLink>; School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101128757%22">The journal of nursing research : JNR</searchLink> [J Nurs Res] 2026 Oct 01; Vol. 34 (5), pp. e476. <i>Date of Electronic Publication: </i>2026 Oct 01. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Validation Study – Name: Language Label: Language Group: Lang Data: English – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott+Williams+%26+Wilkins%22">Lippincott Williams & Wilkins </searchLink><i>Country of Publication: </i>China (Republic : 1949- ) <i>NLM ID: </i>101128757 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1948-965X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216823141%22">16823141 </searchLink><i>NLM ISO Abbreviation: </i>J Nurs Res <i>Subsets: </i>MEDLINE – Name: PublisherInfo Label: Imprint Name(s) Group: PubInfo Data: <i>Publication</i>: March 2009- : Hagerstown, MD : Lippincott Williams & Wilkins<br /><i>Original Publication</i>: Taipei, Taiwan, ROC : Taiwan Nurses Association, [2001- – Name: SubjectMESH Label: MeSH Terms Group: Su Data: <searchLink fieldCode="MM" term="%22Psychometrics%22">Psychometrics*</searchLink>/<searchLink fieldCode="MM" term="%22Psychometrics+standards%22">standards</searchLink> <br /><searchLink fieldCode="MM" term="%22Psychometrics%22">Psychometrics*</searchLink>/<searchLink fieldCode="MM" term="%22Psychometrics+instrumentation%22">instrumentation</searchLink> <br /><searchLink fieldCode="MM" term="%22Psychometrics%22">Psychometrics*</searchLink>/<searchLink fieldCode="MM" term="%22Psychometrics+methods%22">methods</searchLink> <br /><searchLink fieldCode="MM" term="%22Papillomavirus+Infections%22">Papillomavirus Infections*</searchLink>/<searchLink fieldCode="MM" term="%22Papillomavirus+Infections+prevention+%26+control%22">prevention & control</searchLink> <br /><searchLink fieldCode="MM" term="%22Papillomavirus+Infections%22">Papillomavirus Infections*</searchLink>/<searchLink fieldCode="MM" term="%22Papillomavirus+Infections+psychology%22">psychology</searchLink> <br /><searchLink fieldCode="MM" term="%22Students%22">Students*</searchLink>/<searchLink fieldCode="MM" term="%22Students+psychology%22">psychology</searchLink> <br /><searchLink fieldCode="MM" term="%22Students%22">Students*</searchLink>/<searchLink fieldCode="MM" term="%22Students+statistics+%26+numerical+data%22">statistics & numerical data</searchLink> <br /><searchLink fieldCode="MM" term="%22Health+Literacy%22">Health Literacy*</searchLink>/<searchLink fieldCode="MM" term="%22Health+Literacy+standards%22">standards</searchLink> <br /><searchLink fieldCode="MM" term="%22Health+Literacy%22">Health Literacy*</searchLink>/<searchLink fieldCode="MM" term="%22Health+Literacy+statistics+%26+numerical+data%22">statistics & numerical data</searchLink> <br /><searchLink fieldCode="MM" term="%22Health+Literacy%22">Health Literacy*</searchLink>/<searchLink fieldCode="MM" term="%22Health+Literacy+methods%22">methods</searchLink><br /><searchLink fieldCode="MH" term="%22Universities%22">Universities</searchLink>/<searchLink fieldCode="MH" term="%22Universities+organization+%26+administration%22">organization & administration</searchLink> ; <searchLink fieldCode="MH" term="%22Universities%22">Universities</searchLink>/<searchLink fieldCode="MH" term="%22Universities+statistics+%26+numerical+data%22">statistics & numerical data</searchLink> ; <searchLink fieldCode="MH" term="%22Humans%22">Humans</searchLink> ; <searchLink fieldCode="MH" term="%22Taiwan%22">Taiwan</searchLink> ; <searchLink fieldCode="MH" term="%22Female%22">Female</searchLink> ; <searchLink fieldCode="MH" term="%22Reproducibility+of+Results%22">Reproducibility of Results</searchLink> ; <searchLink fieldCode="MH" term="%22Cross-Sectional+Studies%22">Cross-Sectional Studies</searchLink> ; <searchLink fieldCode="MH" term="%22Surveys+and+Questionnaires%22">Surveys and Questionnaires</searchLink> ; <searchLink fieldCode="MH" term="%22Male%22">Male</searchLink> ; <searchLink fieldCode="MH" term="%22Adult%22">Adult</searchLink> ; <searchLink fieldCode="MH" term="%22Young+Adult%22">Young Adult</searchLink> ; <searchLink fieldCode="MH" term="%22Human+Papillomavirus+Viruses%22">Human Papillomavirus Viruses</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Background: Human papillomavirus (HPV) is a common sexually transmitted virus associated with several types of cancer. Because college students are a high-risk group, understanding their health literacy with regard to HPV prevention is critical. However, no suitable measurement tools are currently available for this purpose.<br />Purpose: In this study, an HPV Prevention Health Literacy Scale (HPV-HLS) was developed, and its reliability and validity were assessed.<br />Methods: A cross-sectional design was used, and the developed scale was validated on a sample of 372 college students from two universities in northern Taiwan and one university in central Taiwan. The initial scale comprised 49 items, developed from qualitative interviews and a literature review. After content validity assessment and item analysis, the scale was refined to 37 items. Exploratory factor analysis (EFA) was conducted with 150 participants, followed by confirmatory factor analysis (CFA) with 222 participants. Concurrent validity and internal consistency reliability were assessed. Data were collected from November 2021 to December 2022.<br />Results: The results of the EFA revealed a two-factor model accounted for 60.30% of the total variation, and those of the CFA demonstrated favorable goodness-of-fit indices (GFI = .81, CFI = .92, TLI = .91, RMSEA = .07, and SRMR = .02). Moreover, the average variance extracted (AVE) for the two factors were .56 and .64, respectively, with corresponding composite reliability (CR) values of .96 and .93, indicating excellent convergent validity. Notably, the AVE surpassed the squared product-moment correlation of the corresponding factors, affirming good discriminant validity. The final iteration of the HPV-HLS comprised 21 items with two subscales: comprehension and evaluation of general information and seeking information from health care professionals. Concurrent validity was found between the proposed scale and the Mandarin Multidimensional Health Literacy Questionnaire ( r = .68, p &lt; .001). The HPV-HLS demonstrated good internal consistency (Cronbach's α = .959).<br />Conclusions/implications for Future Practice: After rigorous psychometric testing, the newly developed HPV-HLS demonstrated excellent reliability and validity, establishing it as an objective tool for evaluating HPV prevention health literacy among college students. This HPV-HLS may be used by health care providers and educators to assess health literacy and evaluate the effectiveness of clinical interventions to prevent HPV infection.<br /> (Copyright © 2026 The Author(s). Published by Wolters Kluwer Health, LLC. on behalf of the Taiwan Nurses Association.) – Name: Abstract Label: Competing Interests Group: Ab Data: The authors declare no conflicts of interest. – Name: Ref Label: References Group: RefInfo Data: J Clin Nurs. 2025 Mar;34(3):795-804. (PMID: <searchLink fieldCode="PM" term="%2239128973%22">39128973)</searchLink><br />J Nurs Res. 2024 Oct 01;32(5):e347. (PMID: <searchLink fieldCode="PM" term="%2239177487%22">39177487)</searchLink><br />Sci Rep. 2025 Jul 1;15(1):21048. (PMID: <searchLink fieldCode="PM" term="%2240593150%22">40593150)</searchLink><br />Hum Vaccin Immunother. 2021 Aug 3;17(8):2736-2747. (PMID: <searchLink fieldCode="PM" term="%2233787459%22">33787459)</searchLink><br />J Nurs Res. 2024 Aug 01;32(4):e337. (PMID: <searchLink fieldCode="PM" term="%2239037391%22">39037391)</searchLink><br />J Behav Med. 2024 Apr;47(2):334-341. (PMID: <searchLink fieldCode="PM" term="%2238180576%22">38180576)</searchLink><br />J Pediatr Nurs. 2024 May-Jun;76:124-131. (PMID: <searchLink fieldCode="PM" term="%2238382187%22">38382187)</searchLink><br />J Am Coll Health. 2013;61(1):28-35. (PMID: <searchLink fieldCode="PM" term="%2223305542%22">23305542)</searchLink><br />J Community Health. 2018 Dec;43(6):1192-1200. (PMID: <searchLink fieldCode="PM" term="%2229922992%22">29922992)</searchLink><br />BMC Public Health. 2013 Oct 10;13:948. (PMID: <searchLink fieldCode="PM" term="%2224112855%22">24112855)</searchLink><br />Cult Health Sex. 2024 Jul;26(7):936-951. (PMID: <searchLink fieldCode="PM" term="%2237950430%22">37950430)</searchLink><br />Public Health. 2020 May;182:125-130. (PMID: <searchLink fieldCode="PM" term="%2232272289%22">32272289)</searchLink><br />Fam Med. 1993 Jun;25(6):391-5. (PMID: <searchLink fieldCode="PM" term="%228349060%22">8349060)</searchLink><br />Res Nurs Health. 2007 Aug;30(4):459-67. (PMID: <searchLink fieldCode="PM" term="%2217654487%22">17654487)</searchLink><br />Healthcare (Basel). 2021 Oct 18;9(10):. (PMID: <searchLink fieldCode="PM" term="%2234683071%22">34683071)</searchLink><br />J Multidiscip Healthc. 2024 Jan 30;17:409-418. (PMID: <searchLink fieldCode="PM" term="%2238314013%22">38314013)</searchLink><br />Sex Transm Dis. 2021 Apr 1;48(4):278-284. (PMID: <searchLink fieldCode="PM" term="%2233492104%22">33492104)</searchLink><br />Front Public Health. 2022 Aug 24;10:946889. (PMID: <searchLink fieldCode="PM" term="%2236091498%22">36091498)</searchLink><br />J Adv Nurs. 2025 Apr;81(4):1902-1913. (PMID: <searchLink fieldCode="PM" term="%2239180745%22">39180745)</searchLink><br />Sci Rep. 2023 May 10;13(1):7633. (PMID: <searchLink fieldCode="PM" term="%2237165210%22">37165210)</searchLink><br />Vaccine. 2012 Nov 20;30 Suppl 5:F12-23. (PMID: <searchLink fieldCode="PM" term="%2223199955%22">23199955)</searchLink><br />J Gen Intern Med. 1995 Oct;10(10):537-41. (PMID: <searchLink fieldCode="PM" term="%228576769%22">8576769)</searchLink> – Name: SubjectMinor Label: Contributed Indexing Group: Data: <i>Keywords: </i>HPV; college students; health literacy; human papillomavirus; scale – Name: DateEntry Label: Entry Date(s) Group: Date Data: <i>Date Created: </i>20260828 <i>Date Completed: </i>20260923 <i>Latest Revision: </i>20260926 – Name: DateUpdate Label: Update Code Group: Date Data: 20260926 – Name: PubmedCentralID Label: PubMed Central ID Group: ID Data: PMC13608273 – Name: DOI Label: DOI Group: ID Data: 10.1097/jnr.0000000000000767 – Name: AN Label: PMID Group: ID Data: 42663177 |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1097/jnr.0000000000000767 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e476 Subjects: – SubjectFull: Universities organization & administration Type: general – SubjectFull: Universities statistics & numerical data Type: general – SubjectFull: Humans Type: general – SubjectFull: Taiwan Type: general – SubjectFull: Female Type: general – SubjectFull: Reproducibility of Results Type: general – SubjectFull: Cross-Sectional Studies Type: general – SubjectFull: Surveys and Questionnaires Type: general – SubjectFull: Male Type: general – SubjectFull: Adult Type: general – SubjectFull: Young Adult Type: general – SubjectFull: Human Papillomavirus Viruses Type: general – SubjectFull: Psychometrics standards Type: general – SubjectFull: Psychometrics instrumentation Type: general – SubjectFull: Psychometrics methods Type: general – SubjectFull: Papillomavirus Infections prevention & control Type: general – SubjectFull: Papillomavirus Infections psychology Type: general – SubjectFull: Students psychology Type: general – SubjectFull: Students statistics & numerical data Type: general – SubjectFull: Health Literacy standards Type: general – SubjectFull: Health Literacy statistics & numerical data Type: general – SubjectFull: Health Literacy methods Type: general Titles: – TitleFull: Development and Psychometric Validation of the Human Papillomavirus Prevention Health Literacy Scale for College Students in Taiwan. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lai CY – PersonEntity: Name: NameFull: Yang SC – PersonEntity: Name: NameFull: Liu CY – PersonEntity: Name: NameFull: Lin HR – PersonEntity: Name: NameFull: Liao YM – PersonEntity: Name: NameFull: Lee TY IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: 2026 Oct 01 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1948-965X Numbering: – Type: volume Value: 34 – Type: issue Value: 5 Titles: – TitleFull: The journal of nursing research : JNR Type: main |
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