Academic Journal

Effects of Progressive Inspiratory Muscle Training on Lung Volume and Respiratory Strength in Patients With Pre-Dialysis Chronic Kidney Disease.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Effects of Progressive Inspiratory Muscle Training on Lung Volume and Respiratory Strength in Patients With Pre-Dialysis Chronic Kidney Disease.
Συγγραφείς: Soares de Oliveira M; Post-Graduation Program in Physical Therapy, Health Sciences Center, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil., Moraes de Macêdo T; Post-Graduation Program in Physical Therapy, Health Sciences Center, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil., Ferreira Alves K; Post-Graduation Program in Physical Therapy, Health Sciences Center, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil., Marinho Cunha BL; Post-Graduation Program in Physical Therapy, Health Sciences Center, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil., Xavier Nunes DT; Post-Graduation Program in Physical Therapy, Health Sciences Center, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil., Melo da Silva LM; Post-Graduation Program in Physical Therapy, Health Sciences Center, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil., de Melo Marinho PÉ; Post-Graduation Program in Physical Therapy, Health Sciences Center, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Πηγή: Physiotherapy research international : the journal for researchers and clinicians in physical therapy [Physiother Res Int] 2026 Oct; Vol. 31 (4), pp. e70320.
Τύπος έκδοσης: Journal Article; Randomized Controlled Trial
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 9612022 Publication Model: Print Cited Medium: Internet ISSN: 1471-2865 (Electronic) Linking ISSN: 13582267 NLM ISO Abbreviation: Physiother Res Int Subsets: MEDLINE
Imprint Name(s): Publication: 2006- : Hoboken, NJ : John Wiley & Sons
Original Publication: London ; Lawrence, KS : Whurr Publishers, c1996-
Ιατρικοί όροι (MeSH): Muscle Strength*/physiology , Respiratory Muscles*/physiopathology , Breathing Exercises*/methods , Renal Insufficiency, Chronic*/physiopathology , Renal Insufficiency, Chronic*/rehabilitation, Humans ; Male ; Female ; Middle Aged ; Lung Volume Measurements ; Aged ; Plethysmography ; Treatment Outcome ; Renal Dialysis
Περίληψη: Introduction: Chronic kidney disease can present changes in thoracic cavity volume and respiratory muscle weakness, even in the pre-dialysis stage. However, there is little evidence on the effects of inspiratory muscle training in these patients.
Methods: This was a randomized clinical trial which comprised patients with Chronic Kidney Disease in stages 3, 4, and 5 undergoing conservative treatment, allocated experimental group (EG) with progressive loading (up to 50% of maximal inspiratory pressure [MIP]) and control group (CG) with a fixed load (5 cmH2O) and no load progression performed daily for 8 weeks. The outcomes assessed were thoracic cavity volumes, as measured by optoelectronic plethysmography, and inspiratory and expiratory respiratory muscle strength.
Results: A total of 30 patients completed the study. All volumes significantly increased at the end of the protocol with a large effect size, but only the pulmonary thoracic cavity volume showed a significant interaction (F = 3.698; p = 0.042). There was an increase in inspiratory muscle strength in the EG (73.88-90.35 cmH2O; p < 0.001) and in the CG (70.85-86.92 cmH2O; p = 0.001), as well as in expiratory muscle strength in the EG (97.71-108.53 cmH2O; p = 0.001) and in the CG (80.69-94.77 cmH2O; p = 0.004).
Conclusion: Daily IMT increased thoracoabdominal volumes, particularly pulmonary rib cage volume in the progressive-load group, as well as respiratory muscle strength in patients with pre-dialysis CKD. However, progressive-load IMT was not superior to minimal-load training.
(© 2026 The Author(s). Physiotherapy Research International published by John Wiley & Sons Ltd.)
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Grant Information: 06/2024 PROPESQI
Contributed Indexing: Keywords: breathing exercises; chronic renal failure; lung volumes; plethysmography
Entry Date(s): Date Created: 20260826 Date Completed: 20260827 Latest Revision: 20260911
Update Code: 20260911
PubMed Central ID: PMC13518542
DOI: 10.1002/pri.70320
PMID: 42649477
Βάση Δεδομένων: MEDLINE