Academic Journal
Neural computations in the foveal and peripheral visual fields during active search.
| Τίτλος: | Neural computations in the foveal and peripheral visual fields during active search. |
|---|---|
| Συγγραφείς: | Zhang J; Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.; Network Intelligence Research, Peng Cheng Laboratory, Shenzhen, China.; University of Chinese Academy of Sciences, Beijing, China., Zhu X; Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.; University of Chinese Academy of Sciences, Beijing, China., Ma Z; Network Intelligence Research, Peng Cheng Laboratory, Shenzhen, China., Wang S; Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China., Wang Y; University of Chinese Academy of Sciences, Beijing, China.; Faculty of Life and Health Sciences, Shenzhen University of Advanced Technology, Shenzhen, China., Esteky H; Research Group for Brain and Cognitive Sciences, School of Medicine, Shahid Beheshti University, Tehran, Iran., Tian Y; Network Intelligence Research, Peng Cheng Laboratory, Shenzhen, China., Zhou H; Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.; Network Intelligence Research, Peng Cheng Laboratory, Shenzhen, China. |
| Πηγή: | ELife [Elife] 2026 Aug 20; Vol. 15. Date of Electronic Publication: 2026 Aug 20. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Cambridge, UK : eLife Sciences Publications, Ltd., 2012- |
| Ιατρικοί όροι (MeSH): | Visual Fields*/physiology , Fovea Centralis*/physiology , Attention*/physiology , Visual Perception*/physiology , Visual Cortex*/physiology, Fixation, Ocular/physiology ; Animals ; Macaca mulatta ; Saccades ; Photic Stimulation ; Male |
| Περίληψη: | Active vision requires coordinated attentional processing across both foveal and peripheral receptive fields (RFs), yet the underlying neural dynamics and computational mechanisms remain poorly understood. Previous research has predominantly focused on attention in the visual periphery, leaving the role of foveal processing in naturalistic tasks largely unexplored. Here, we recorded neural activity from both foveal and peripheral RFs in areas V4 and IT of monkeys during free-gaze visual search among complex stimuli. We found robust feature-based attentional enhancements in foveal units, challenging the prevailing view that such modulation is predominantly peripheral. By integrating data from foveal and peripheral recordings, we revealed a non-uniform, dynamically distributed pattern of feature attention across the visual field. Behaviorally, foveal attentional enhancements promoted sustained or repeated fixations on targets, while peripheral attentional signals facilitated target detection and guidance of future saccades. These findings suggest that foveal and peripheral attention operate in a complementary fashion and highlight the critical role of foveal feature attention in shaping global attention allocation and fixation behavior during active vision. This work advances our understanding of the neural computations that support complex visual search and underscores the need to account for foveal processing in models of attention. (© 2026, Zhang, Zhu, Ma et al.) |
| Competing Interests: | JZ, XZ, ZM, SW, YW, HE, YT, HZ No competing interests declared |
| References: | Trends Neurosci. 2006 Jun;29(6):317-22. (PMID: 16697058) Curr Biol. 2018 Jul 9;28(13):2058-2069.e4. (PMID: 29910078) Brain. 2019 Nov 1;142(11):3530-3549. (PMID: 31549164) J Cogn Neurosci. 2004 Jan-Feb;16(1):4-14. (PMID: 15006031) J Neurosci. 2001 Feb 15;21(4):1340-50. (PMID: 11160405) Curr Biol. 2004 May 4;14(9):744-51. (PMID: 15120065) Nat Neurosci. 2016 Apr;19(4):613-22. (PMID: 26900926) J Neurophysiol. 1998 Dec;80(6):2918-40. (PMID: 9862896) J Exp Psychol Hum Percept Perform. 2008 Oct;34(5):1078-91. (PMID: 18823196) Cell. 2017 Jun 1;169(6):1013-1028.e14. (PMID: 28575666) Sci Adv. 2025 Mar 21;11(12):eadq0332. (PMID: 40117351) Neuron. 2011 Jun 23;70(6):1205-17. (PMID: 21689605) Nature. 1999 Oct 7;401(6753):584-7. (PMID: 10524624) Neuroimage. 2003 Jul;19(3):496-512. (PMID: 12880783) Ophthalmic Physiol Opt. 1988;8(3):345-8. (PMID: 3269513) Nat Commun. 2019 Dec 16;10(1):5727. (PMID: 31844117) Neuron. 2007 Jul 19;55(2):301-12. (PMID: 17640530) Nat Neurosci. 2009 Sep;12(9):1187-96. (PMID: 19668199) Nature. 2020 Jul;583(7814):103-108. (PMID: 32494012) Science. 2010 Nov 5;330(6005):845-51. (PMID: 21051642) Psychon Bull Rev. 2021 Aug;28(4):1252-1260. (PMID: 33687666) Nat Neurosci. 2013 Jun;16(6):763-70. (PMID: 23603707) Neuron. 2003 Dec 18;40(6):1241-50. (PMID: 14687556) Science. 2014 Apr 25;344(6182):424-7. (PMID: 24763592) Front Neurosci. 2017 Sep 29;11:545. (PMID: 29033784) Nature. 2011 May 15;474(7351):372-5. (PMID: 21572439) Nature. 1999 Jun 10;399(6736):575-9. (PMID: 10376597) Commun Biol. 2024 Oct 4;7(1):1259. (PMID: 39367101) PLoS Biol. 2019 Aug 6;17(8):e3000387. (PMID: 31386656) Curr Biol. 2007 Dec 4;17(23):2067-72. (PMID: 17997310) J Neurophysiol. 2000 Mar;83(3):1751-5. (PMID: 10712494) J Vis. 2018 Oct 1;18(11):16. (PMID: 30357345) Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8619-24. (PMID: 24812127) Optom Vis Sci. 2012 Sep;89(9):1385-94. (PMID: 22885785) J Neurophysiol. 1996 Dec;76(6):4040-55. (PMID: 8985899) J Vis. 2008 Oct 23;8(14):9.1-9. (PMID: 19146310) Science. 2007 Mar 30;315(5820):1860-2. (PMID: 17395832) Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8755-E8764. (PMID: 30154164) Annu Rev Vis Sci. 2022 Sep 15;8:407-425. (PMID: 35679625) Vision Res. 2018 Jan;142:1-10. (PMID: 29183779) Vision Res. 2010 Jun 18;50(13):1225-34. (PMID: 20382174) Psychon Bull Rev. 2021 Aug;28(4):1060-1092. (PMID: 33547630) Psychophysiology. 2020 Mar;57(3):e13498. (PMID: 31691314) Neuroimage. 2022 Apr 1;249:118900. (PMID: 35021039) R Soc Open Sci. 2020 Jan 29;7(1):191553. (PMID: 32218974) J Neurosci. 2024 Nov 13;44(46):. (PMID: 39327006) Sci Data. 2025 May 13;12(1):779. (PMID: 40355416) Trends Cogn Sci. 2014 Oct;18(10):526-35. (PMID: 24930047) Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):E291-9. (PMID: 24385588) Nature. 2009 Jul 2;460(7251):94-7. (PMID: 19506558) Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2202564119. (PMID: 36161937) Science. 2019 May 3;364(6439):. (PMID: 31048462) Nat Neurosci. 2007 Jul;10(7):903-7. (PMID: 17589507) Proc Natl Acad Sci U S A. 2023 Feb 28;120(9):e2210839120. (PMID: 36812207) Science. 2005 Apr 22;308(5721):529-34. (PMID: 15845848) J Exp Psychol Hum Percept Perform. 1989 Aug;15(3):419-33. (PMID: 2527952) Optom Vis Sci. 2005 Jan;82(1):27-35. (PMID: 15630401) Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):. (PMID: 33431673) J Neurosci. 2015 Jul 15;35(28):10146-53. (PMID: 26180191) J Vis. 2015;15(16):1. (PMID: 26624936) J Neurosci. 2014 Feb 26;34(9):3390-401. (PMID: 24573295) Sci Rep. 2018 Oct 31;8(1):16132. (PMID: 30382137) Nat Commun. 2021 Nov 9;12(1):6456. (PMID: 34753913) Vision Res. 2009 Jun;49(10):1182-7. (PMID: 18619996) Percept Psychophys. 2000 Apr;62(3):576-85. (PMID: 10909248) Curr Biol. 2002 Jul 9;12(13):1134-7. (PMID: 12121622) Neuron. 2015 Nov 18;88(4):832-44. (PMID: 26526392) Neuron. 2011 Jun 23;70(6):1192-204. (PMID: 21689604) J Neurosci. 2022 Aug 31;42(35):6782-6799. (PMID: 35863889) PLoS One. 2020 Aug 4;15(8):e0236967. (PMID: 32750065) Curr Biol. 2021 Jul 12;31(13):2785-2795.e4. (PMID: 33951457) Neuron. 2008 Aug 14;59(3):509-21. (PMID: 18701075) Elife. 2022 Jan 28;11:. (PMID: 35089128) |
| Grant Information: | 62027804 National Natural Science Foundation of China; 62206141 National Natural Science Foundation of China; 31671108 National Natural Science Foundation of China; 62236009 National Natural Science Foundation of China; 172644KYSB20160175 International Partnership Program of the Chinese Academy of Sciences; JCYJ20200109114805984 Shenzhen Fundamental Research Program |
| Contributed Indexing: | Keywords: attention; category selectivity; foveal; macaques; neuroscience; peripheral; rhesus macaque; visual search |
| Entry Date(s): | Date Created: 20260820 Date Completed: 20260820 Latest Revision: 20260822 |
| Update Code: | 20260822 |
| PubMed Central ID: | PMC13493125 |
| DOI: | 10.7554/eLife.109498 |
| PMID: | 42622516 |
| Βάση Δεδομένων: | MEDLINE |
καταχωρήστε σχόλιο πρώτοι!