Endoleak detection with photon-counting detector CT at various radiation doses after endovascular aneurysm repair: a phantom study.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Endoleak detection with photon-counting detector CT at various radiation doses after endovascular aneurysm repair: a phantom study.
Συγγραφείς: Huber AT; Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.; Department of Radiology and Nuclear Medicine, University Teaching and Research Hospital, Luzerner Kantonsspital, University of Lucerne, Lucerne, Switzerland., Szucs-Farkas G; University of Bern, Bern, Switzerland., Perrin LG; Department of Radiology, Hospital Centre of Biel, Biel/Bienne, Switzerland., M'Hamdi B; Department of Radiology, Hospital Centre of Biel, Biel/Bienne, Switzerland., Bespyatova S; Department of Radiology, Hospital Centre of Biel, Biel/Bienne, Switzerland., Christe A; Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Szucs-Farkas Z; Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. zsolt.szuecs@szb-chb.ch.; Department of Radiology, Hospital Centre of Biel, Biel/Bienne, Switzerland. zsolt.szuecs@szb-chb.ch.
Πηγή: The international journal of cardiovascular imaging [Int J Cardiovasc Imaging] 2026 Oct; Vol. 42 (10), pp. 1933-1944. Date of Electronic Publication: 2026 Aug 13.
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Springer Country of Publication: United States NLM ID: 100969716 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8312 (Electronic) Linking ISSN: 15695794 NLM ISO Abbreviation: Int J Cardiovasc Imaging Subsets: MEDLINE
Imprint Name(s): Publication: [New York] : Springer
Original Publication: Boston : Kluwer Academic Publishers, c2001-
Ιατρικοί όροι (MeSH): Endoleak*/diagnostic imaging , Endoleak*/etiology , Endovascular Aneurysm Repair*/adverse effects , Endovascular Aneurysm Repair*/instrumentation , Aortography*/instrumentation , Aortography*/methods , Computed Tomography Angiography*/instrumentation , Radiation Exposure*/adverse effects , Radiation Exposure*/prevention & control , Aortic Aneurysm, Abdominal*/surgery , Aortic Aneurysm, Abdominal*/diagnostic imaging , Blood Vessel Prosthesis Implantation*/adverse effects , Blood Vessel Prosthesis Implantation*/instrumentation , Radiation Dosage* , Phantoms, Imaging* , Photons*, Predictive Value of Tests ; Humans ; Radiographic Image Interpretation, Computer-Assisted ; Reproducibility of Results ; Observer Variation
Περίληψη: After endovascular aneurysm repair, patients require lifelong CT follow-ups. Photon-counting detector CT (PCD-CT) may improve detection of tiny iodinated structures at low radiation dose. The aim of this experimental study was to find the lowest dose which still provides high detectability of small endoleaks using PCD-CT with 55 keV and 50 keV virtual monoenergetic images (VMIs). An abdominal aneurysm phantom mimicking medium and large patients was scanned at 100%, 50%, 25%, and 12.5% radiation dose using PCD-CT. Besides standard 55 keV images, 50 keV VMI were reconstructed at 25% and 12.5% dose. The ninety-six CT series containing 1728 endoleaks of 2-6 mm were read by three independent observers. Areas under the alternative free-response operational characteristic curve (A1) were analysed with the jackknife-method. In the medium phantom, A1 for 6 mm endoleaks was similar at 100% and 50% doses (0.93 vs. 0.86; p = 0.23), but performance at 50% dose decreased in 4-6 mm endoleaks (A1, 0.81 vs. 0.68; p = 0.02). In the large phantom, A1 decreased at 50% dose both for 6 mm (0.72 vs. 0.42; p = 0.003) and for 4-6 mm (0.49 vs. 0.29; p = 0.02) endoleaks. Compared with standard reconstruction, 50 keV VMIs did not change A1 at 25% dose (0.56 vs. 0.52; p = 0.38) and led to worse performance at 12.5% dose (0.30 vs. 0.19; p = 0.01). In summary, diagnostic performance for 6 mm endoleaks remained high with 50%-dose reduction using PCD-CT in simulated medium but not in large patients. 50 keV VMIs at 12.5% and 25% dose did not improve endoleak detection.
(© 2026. The Author(s).)
Competing Interests: Declarations. Competing interests: The authors declare no competing interests.
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Contributed Indexing: Keywords: Abdominal aortic aneurysm; CT Angiography; Endoleak; Phantom study; Photon- counting- detector CT
Entry Date(s): Date Created: 20260813 Date Completed: 20261007 Latest Revision: 20261010
Update Code: 20261010
PubMed Central ID: PMC13645996
DOI: 10.1007/s10554-026-03765-y
PMID: 42593657
Βάση Δεδομένων: MEDLINE