Academic Journal
Integrated chromatographic and chemometric evaluation of lipophilicity in steroidal hydrazone derivatives across multiple mobile phase systems.
| Τίτλος: | Integrated chromatographic and chemometric evaluation of lipophilicity in steroidal hydrazone derivatives across multiple mobile phase systems. |
|---|---|
| Συγγραφείς: | Mosić MD; University of Belgrade - Faculty of Chemistry, Studentski trg 12-16, 11158, Belgrade, Serbia. Electronic address: mosicm@chem.bg.ac.rs., Nastić MA; University of Niš, Faculty of Sciences and Mathematics, Department of Biology and Ecology, Višegradska 33, 18000, Niš, Serbia., Živković MB; University of Belgrade - Institute of Chemistry, Technology and Metallurgy, Department of Chemistry, Njegoševa 12, 11000, Belgrade, Serbia., Mitreski KL; University of Belgrade - Faculty of Chemistry, Studentski trg 12-16, 11158, Belgrade, Serbia., Šegan SB; University of Belgrade - Institute of Chemistry, Technology and Metallurgy, Department of Chemistry, Njegoševa 12, 11000, Belgrade, Serbia. Electronic address: sandra.segan@ihtm.bg.ac.rs. |
| Πηγή: | Journal of chromatography. A [J Chromatogr A] 2026 Oct 11; Vol. 1786, pp. 467342. Date of Electronic Publication: 2026 Aug 07. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9318488 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3778 (Electronic) Linking ISSN: 00219673 NLM ISO Abbreviation: J Chromatogr A Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Amsterdam ; New York : Elsevier, 1993- |
| Ιατρικοί όροι (MeSH): | Steroids*/chemistry , Hydrazones*/chemistry, Chromatography, Thin Layer/methods ; Chromatography, Reverse-Phase/methods ; Emulsions/chemistry ; Hydrophobic and Hydrophilic Interactions ; Micelles ; Acetonitriles |
| Περίληψη: | The retention behavior of structurally related steroidal semicarbazones, thiadiazolines, thiazolidin-4-ones, and monoethyl carbazate esters was investigated using thin-layer chromatography on octadecyl-silica (RP18) under reversed-phase (RP), micellar, microemulsion, and acetonitrile/phosphate-buffered saline (pH 7.4) mobile phase conditions. Classical binary methanol-water and acetone-water systems were used to determine R (Copyright © 2026 Elsevier B.V. All rights reserved.) |
| Competing Interests: | Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. |
| Contributed Indexing: | Keywords: Lipophilicity; Micellar liquid chromatography (MLC); Microemulsion liquid chromatography (MELC); Reversed-phase thin-layer chromatography (RP-TLC); Steroidal hydrazone derivatives |
| Substance Nomenclature: | 0 (Steroids) 0 (Hydrazones) 0 (Micelles) 0 (Emulsions) Z072SB282N (acetonitrile) 0 (Acetonitriles) |
| Entry Date(s): | Date Created: 20260811 Date Completed: 20260907 Latest Revision: 20260907 |
| Update Code: | 20260908 |
| DOI: | 10.1016/j.chroma.2026.467342 |
| PMID: | 42580232 |
| Βάση Δεδομένων: | MEDLINE |
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