Academic Journal
Multienvironment multilocus association mapping reveals genomic regions for drought-related traits in tropical maize.
| Τίτλος: | Multienvironment multilocus association mapping reveals genomic regions for drought-related traits in tropical maize. |
|---|---|
| Συγγραφείς: | Anoni CO; Departamento de Genética, Escola Superior de Agricultura Luiz de Queiroz, Universidade de São Paulo (ESALQ/USP), Av. Pádua Dias 11, Piracicaba, São Paulo 13418-900, Brazil., Dias KODG; Departamento de Biologia Geral, Universidade Federal de Viçosa, Av. PH Rolfs s/n, Viçosa, Minas Gerais 36570-900, Brazil., Boer M; Biometris, Wageningen University and Research Center, Droevendaalsesteeg 2, Wageningen 6708 PB, The Netherlands., Malosetti M; Biometris, Wageningen University and Research Center, Droevendaalsesteeg 2, Wageningen 6708 PB, The Netherlands.; BASF - Nunhems, Napoleonsweg 152, Nunhem 6083 AB, The Netherlands., Guimarães LJM; Embrapa Milho e Sorgo, Rodovia MG424, km 65, Sete Lagoas, Minas Gerais 35702-098, Brazil., Guimarães PEO; Embrapa Milho e Sorgo, Rodovia MG424, km 65, Sete Lagoas, Minas Gerais 35702-098, Brazil., Viana MJA; Embrapa Milho e Sorgo, Rodovia MG424, km 65, Sete Lagoas, Minas Gerais 35702-098, Brazil., Mudadu MA; Embrapa Milho e Sorgo, Rodovia MG424, km 65, Sete Lagoas, Minas Gerais 35702-098, Brazil., Bastos EA; Embrapa Meio Norte, Rua Duque de Caxias 5650, Teresina, Piauí 64008-780, Brazil., Cardoso MJ; Embrapa Meio Norte, Rua Duque de Caxias 5650, Teresina, Piauí 64008-780, Brazil., Noda RW; Embrapa Milho e Sorgo, Rodovia MG424, km 65, Sete Lagoas, Minas Gerais 35702-098, Brazil., Yassitepe JECT; Embrapa Agricultura Digital, Av. André Tosello 209, Campinas, São Paulo 13083-886, Brazil., de Magalhaes JV; Embrapa Milho e Sorgo, Rodovia MG424, km 65, Sete Lagoas, Minas Gerais 35702-098, Brazil., Garcia AAF; Departamento de Genética, Escola Superior de Agricultura Luiz de Queiroz, Universidade de São Paulo (ESALQ/USP), Av. Pádua Dias 11, Piracicaba, São Paulo 13418-900, Brazil., van Eeuwijk F; Biometris, Wageningen University and Research Center, Droevendaalsesteeg 2, Wageningen 6708 PB, The Netherlands., Guimarães CT; Embrapa Milho e Sorgo, Rodovia MG424, km 65, Sete Lagoas, Minas Gerais 35702-098, Brazil., Pastina MM; Embrapa Milho e Sorgo, Rodovia MG424, km 65, Sete Lagoas, Minas Gerais 35702-098, Brazil. |
| Πηγή: | G3 (Bethesda, Md.) [G3 (Bethesda)] 2026 Oct 07; Vol. 16 (10). |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Oxford University Press Country of Publication: England NLM ID: 101566598 Publication Model: Print Cited Medium: Internet ISSN: 2160-1836 (Electronic) Linking ISSN: 21601836 NLM ISO Abbreviation: G3 (Bethesda) Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2021- : [Oxford] : Oxford University Press Original Publication: Bethesda, MD : Genetics Society of America, 2011- |
| Ιατρικοί όροι (MeSH): | Zea mays*/genetics , Zea mays*/physiology , Droughts* , Quantitative Trait Loci* , Chromosome Mapping* , Gene-Environment Interaction* , Genome, Plant* , Quantitative Trait, Heritable*, Stress, Physiological/genetics ; Genomics/methods ; Polymorphism, Single Nucleotide ; Genome-Wide Association Study ; Phenotype ; Drought Resistance ; Tropical Climate ; Genotype ; Genetic Association Studies ; Environment |
| Περίληψη: | Maize grain yield is frequently constrained by water scarcity, particularly in tropical regions characterized by irregular rainfall patterns. Dissecting the genetic basis of drought-related traits remains challenging because their expression is strongly influenced by environmental conditions. In this study, we applied a multienvironment multilocus genome-wide association study to identify genomic regions associated with drought-related traits in tropical maize. The association panel comprised 190 inbred lines from the Embrapa breeding program, which were genotyped-by-sequencing with 500,108 single nucleotide polymorphisms (SNPs) and crossed with 2 tester lines. Phenotypic data corresponded to the performance of the testcross hybrids, divided into Dent and Flint heterotic groups, evaluated across 2 yr at 2 locations in Brazil under well-watered and water-stressed conditions. Traits analyzed included grain yield, anthesis-silking interval, female and male flowering time, and plant and ear height. Drought stress reduced grain yield by approximately 50% and increased the anthesis-silking interval by about 2 d. A total of 179 significant SNP-trait associations were detected, of which 166 showed significant SNP-by-environment interaction effects, while 13 displayed stable effects across environments. Several associations were detected specifically under water-stressed conditions, highlighting genomic regions potentially involved in drought adaptation. Functional annotation revealed candidate genes previously implicated in abiotic stress responses, including ZmTIP1, which encodes an S-acyltransferase regulating root hair development and drought tolerance. Among the novel candidate genes, GRMZM2G159125, encoding a phospholipase D, emerged as a particularly promising candidate due to its strong association with grain yield and its role in membrane lipid signaling pathways related to stress responses. Although a few associations overlapped genomic regions previously reported for drought tolerance in maize, most loci represent potentially novel genetic factors that may contribute to improving drought resilience in tropical maize breeding programs. (© The Author(s) 2026. Published by Oxford University Press on behalf of The Genetics Society of America.) |
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| Grant Information: | Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Conselho Nacional de Desenvolvimento Científico e Tecnológico; CAPES; Embrapa and Generation Challenge Programme |
| Contributed Indexing: | Keywords: Zea mays; GWAS; multienvironment trial analysis; water deficiency |
| Entry Date(s): | Date Created: 20260810 Date Completed: 20261007 Latest Revision: 20261009 |
| Update Code: | 20261009 |
| PubMed Central ID: | PMC13643811 |
| DOI: | 10.1093/g3journal/jkag220 |
| PMID: | 42574601 |
| Βάση Δεδομένων: | MEDLINE |
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