Academic Journal
Geographical and temporal patterns of cutaneous leishmaniasis in Pakistan: insight from a decade of epidemiology.
| Τίτλος: | Geographical and temporal patterns of cutaneous leishmaniasis in Pakistan: insight from a decade of epidemiology. |
|---|---|
| Συγγραφείς: | Shaheen R; Department of Biosciences, University of Wah, Wah Cantt, 47040, Pakistan., Bibi R; Department of Biosciences, University of Wah, Wah Cantt, 47040, Pakistan., Aurongzeb M; Department of Applied Sciences, Faculty of Engineering Sciences and Technology (FEST), Hamdard University, Karachi, 74600, Pakistan., Rashid Y; Department of Public Health, Health Services Academy, Islamabad, 44000, Pakistan., Khan M; Department of Biochemistry, University of Karachi, Karachi, 75270, Pakistan., Hussain SI; Department of Zoology, Federal Urdu University of Arts, Science and Technology, Gulshan-e-Iqbal, Karachi, 75300, Pakistan., Naz S; Department of Biotechnology, National University of Medical Sciences, Rawalpindi, 46000, Pakistan. |
| Πηγή: | Transactions of the Royal Society of Tropical Medicine and Hygiene [Trans R Soc Trop Med Hyg] 2026 Oct 05; Vol. 120 (10), pp. 995-1005. |
| Τύπος έκδοσης: | Journal Article; Systematic Review |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Oxford University Press Country of Publication: England NLM ID: 7506129 Publication Model: Print Cited Medium: Internet ISSN: 1878-3503 (Electronic) Linking ISSN: 00359203 NLM ISO Abbreviation: Trans R Soc Trop Med Hyg Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2013- : Oxford : Oxford University Press Original Publication: 1920- : London : Royal Society of Tropical Medicine and Hygiene |
| Ιατρικοί όροι (MeSH): | Leishmaniasis, Cutaneous*/epidemiology, Pakistan/epidemiology ; Leishmania major/isolation & purification ; Humans ; Prevalence ; Risk Factors ; Male ; Female ; Leishmania tropica ; Incidence |
| Περίληψη: | Background: Cutaneous leishmaniasis (CL) is a major public health concern in Pakistan. This systematic review aimed to assess geographical distribution, prevalence trends and epidemiological risk factors associated with CL from 2014 to 2024. Methods: A systematic literature search was conducted using PubMed, ScienceDirect and Google Scholar for studies published from January 2014 to December 2024. Keywords included 'cutaneous leishmaniasis', 'epidemiology', 'Pakistan' and 'geographical distribution'. Of 1000 retrieved publications, 600 were screened and 25 met predefined inclusion and quality criteria. The extracted data included study area, research design, diagnostic methods, gender distribution and Leishmania species. Results: A total of 27 380 confirmed CL cases were reported. The highest burden was in Khyber Pakhtunkhwa (60%), followed by Balochistan (16%), Sindh (8%), Punjab (8%) and Azad Jammu and Kashmir and Chitral (4%). A male predominance (approximately 60-65%) was reported. The dominant species were Leishmania tropica and Leishmania major. Diagnosis relied mainly on microscopy (80%), with an annual incidence rate of 8-10% over the previous decade. Conclusions: CL shows a widespread and increasing distribution pattern in Pakistan. The main factors involve poverty, vectors, climate change and migration. These findings focus on the need to improve the surveillance network, molecular diagnostic methods and public awareness to decrease the growing impact of the disease. (© The Author(s) 2026. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site-for further information please contact journals.permissions@oup.com.) |
| Contributed Indexing: | Keywords: Leishmania species; Pakistan; cutaneous leishmaniasis; geographical distribution; prevalence |
| Entry Date(s): | Date Created: 20260807 Date Completed: 20261005 Latest Revision: 20261005 |
| Update Code: | 20261005 |
| DOI: | 10.1093/trstmh/trag085 |
| PMID: | 42565274 |
| Βάση Δεδομένων: | MEDLINE |
καταχωρήστε σχόλιο πρώτοι!