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Characterizing electronic noise interference from the external laser positioning system on a radiation therapy MRI simulation scanner.

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Τίτλος: Characterizing electronic noise interference from the external laser positioning system on a radiation therapy MRI simulation scanner.
Συγγραφείς: McCullum L; UT MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Houston, Texas, USA.; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Ding Y; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Fuller CD; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Taylor BA; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Πηγή: Journal of applied clinical medical physics [J Appl Clin Med Phys] 2026 Aug; Vol. 27 (8), pp. e70731.
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Wiley on behalf of American Association of Physicists in Medicine Country of Publication: United States NLM ID: 101089176 Publication Model: Print Cited Medium: Internet ISSN: 1526-9914 (Electronic) Linking ISSN: 15269914 NLM ISO Abbreviation: J Appl Clin Med Phys Subsets: MEDLINE
Imprint Name(s): Publication: 2017- : Malden, MA : Wiley on behalf of American Association of Physicists in Medicine
Original Publication: Reston, VA : American College of Medical Physics, c2000-
Ιατρικοί όροι (MeSH): Magnetic Resonance Imaging*/methods , Magnetic Resonance Imaging*/instrumentation , Radiotherapy Planning, Computer-Assisted*/methods , Image Processing, Computer-Assisted*/methods , Patient Positioning*/instrumentation , Phantoms, Imaging* , Lasers*, Radiotherapy, Intensity-Modulated/methods ; Humans ; Signal-To-Noise Ratio ; Radiotherapy Dosage ; Computer Simulation
Περίληψη: Background: Magnetic resonance imaging (MRI) for radiation therapy treatment planning is currently being used in many anatomical sites to better visualize soft tissue landmarks, a technique known as an MRI simulation. A core component of modern MRI simulation configurations are the use of external laser positioning systems (ELPS) to help set up the patient. Though necessary for accurate and reproducible patient setup, the ELPS, if left on during imaging, may interfere negatively with image quality due to leaking electronic noise, of which MRI is sensitive to.
Purpose: It is currently unknown whether this leakage of electronic noise may further affect quantitative values derived from clinically employed relaxometric, diffusion, and fat fraction sequences. Therefore, in this study, we aim to characterize the impact of MRI simulation lasers on general image quality and quantitative imaging accuracy.
Methods: First, a cine acquisition was used to visualize the real-time changes in image signal-to-noise ratio (SNR) from when the ELPS was deactivated to activated. To validate this effect quantitatively, the SNR was measured using the American College of Radiology (ACR) recommended T1-weighted protocol in a homogeneous phantom with the integrated body, 18-channel UltraFlex small, 18-channel UltraFlex large, 32-channel spine, and 16-channel shoulder coils. Next, a geometric distortion algorithm was tested in two vendor-provided phantoms while using the integrated body coil and the ACR Large Phantom protocol was tested. Finally, a series of quantitative MRI scans were performed using a CaliberMRI Model 137 Mini Hybrid phantom to validate quantitative T1, T2, and ADC while a Calimetrix PDFF-R2* phantom was used for quantitative PDFF and R2*. All scans were performed with both the ELPS both deactivated and activated.
Results: Visible electronic noise artifacts were seen when using the integrated body coil when the ELPS was activated on the cine acquisition which led to a two-fold decrease in SNR using the ACR protocol, however geometric distortion quantification was not affected. This SNR drop was not seen when using the remaining tested coils. Degradation in image intensity uniformity, percent signal ghosting, and low contrast object detectability was seen during ACR Large Phantom testing using the 20-channel Head/Neck coil. Concordance across quantitative MRI values was similar when the ELPS was both deactivated and activated while a consistent increase in standard deviation inside the ADC vials was seen when the ELPS was activated.
Conclusions: The extra noise induced from the activation of the ELPS during imaging should be avoided due to its potential to unnecessarily increase image noise. This is particularly true when conducting mandatory quality assurance testing for image quality and geometric distortion which utilize the integrated body coil which is most susceptible to ELPS-induced noise. Clear clinical guidelines should be implemented to make this issue known to the MRI technologists, physicists, and other relevant staff using an MRI with a supplementary ELPS for patient alignment.
(© 2026 The Author(s). Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine.)
References: Magn Reson Med. 2008 Aug;60(2):320-9. (PMID: 18666127)
Magn Reson Imaging. 2013 Jun;31(5):669-75. (PMID: 23290478)
J Magn Reson Imaging. 2013 Jul;38(1):2-11. (PMID: 23633246)
Radiother Oncol. 2023 Aug;185:109717. (PMID: 37211282)
Radiology. 1989 Oct;173(1):265-7. (PMID: 2781018)
HPB (Oxford). 2017 Aug;19(8):706-712. (PMID: 28528267)
Nat Methods. 2012 Jul;9(7):671-5. (PMID: 22930834)
Br J Radiol. 2018 May;91(1085):20170671. (PMID: 29376736)
Magn Reson Med. 2002 Jun;47(6):1202-10. (PMID: 12111967)
Magn Reson Med. 2024 Feb;91(2):741-759. (PMID: 37814776)
Magn Reson Med. 2021 Feb;85(2):734-747. (PMID: 32783200)
Magn Reson Imaging. 2012 Nov;30(9):1323-41. (PMID: 22770690)
Magn Reson Med. 2008 Oct;60(4):895-907. (PMID: 18816810)
J Clin Imaging Sci. 2024 Sep 05;14:33. (PMID: 39371545)
J Magn Reson Imaging. 2013 Aug;38(2):269-87. (PMID: 23960007)
Br J Radiol. 2015;88(1056):20150487. (PMID: 26402216)
J Appl Clin Med Phys. 2015 Mar 08;16(2):5201. (PMID: 26103190)
Radiother Oncol. 2023 Jun;183:109641. (PMID: 36990394)
J Appl Clin Med Phys. 2025 Jul;26(7):e70134. (PMID: 40645191)
Biometrics. 1989 Mar;45(1):255-68. (PMID: 2720055)
Magn Reson Med. 2002 Jan;47(1):42-52. (PMID: 11754441)
Contributed Indexing: Keywords: MRI simulation; external laser positioning system; magnetic resonance imaging; quantitative imaging
Entry Date(s): Date Created: 20260807 Date Completed: 20260807 Latest Revision: 20260813
Update Code: 20260814
PubMed Central ID: PMC13447718
DOI: 10.1002/acm2.70731
PMID: 42563263
Βάση Δεδομένων: MEDLINE
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  Data: Characterizing electronic noise interference from the external laser positioning system on a radiation therapy MRI simulation scanner.
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  Data: <searchLink fieldCode="AU" term="%22McCullum+L%22">McCullum L</searchLink>; UT MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Houston, Texas, USA.; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Ding+Y%22">Ding Y</searchLink>; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Fuller+CD%22">Fuller CD</searchLink>; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Taylor+BA%22">Taylor BA</searchLink>; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
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  Data: Background: Magnetic resonance imaging (MRI) for radiation therapy treatment planning is currently being used in many anatomical sites to better visualize soft tissue landmarks, a technique known as an MRI simulation. A core component of modern MRI simulation configurations are the use of external laser positioning systems (ELPS) to help set up the patient. Though necessary for accurate and reproducible patient setup, the ELPS, if left on during imaging, may interfere negatively with image quality due to leaking electronic noise, of which MRI is sensitive to.<br />Purpose: It is currently unknown whether this leakage of electronic noise may further affect quantitative values derived from clinically employed relaxometric, diffusion, and fat fraction sequences. Therefore, in this study, we aim to characterize the impact of MRI simulation lasers on general image quality and quantitative imaging accuracy.<br />Methods: First, a cine acquisition was used to visualize the real-time changes in image signal-to-noise ratio (SNR) from when the ELPS was deactivated to activated. To validate this effect quantitatively, the SNR was measured using the American College of Radiology (ACR) recommended T1-weighted protocol in a homogeneous phantom with the integrated body, 18-channel UltraFlex small, 18-channel UltraFlex large, 32-channel spine, and 16-channel shoulder coils. Next, a geometric distortion algorithm was tested in two vendor-provided phantoms while using the integrated body coil and the ACR Large Phantom protocol was tested. Finally, a series of quantitative MRI scans were performed using a CaliberMRI Model 137 Mini Hybrid phantom to validate quantitative T1, T2, and ADC while a Calimetrix PDFF-R2* phantom was used for quantitative PDFF and R2*. All scans were performed with both the ELPS both deactivated and activated.<br />Results: Visible electronic noise artifacts were seen when using the integrated body coil when the ELPS was activated on the cine acquisition which led to a two-fold decrease in SNR using the ACR protocol, however geometric distortion quantification was not affected. This SNR drop was not seen when using the remaining tested coils. Degradation in image intensity uniformity, percent signal ghosting, and low contrast object detectability was seen during ACR Large Phantom testing using the 20-channel Head/Neck coil. Concordance across quantitative MRI values was similar when the ELPS was both deactivated and activated while a consistent increase in standard deviation inside the ADC vials was seen when the ELPS was activated.<br />Conclusions: The extra noise induced from the activation of the ELPS during imaging should be avoided due to its potential to unnecessarily increase image noise. This is particularly true when conducting mandatory quality assurance testing for image quality and geometric distortion which utilize the integrated body coil which is most susceptible to ELPS-induced noise. Clear clinical guidelines should be implemented to make this issue known to the MRI technologists, physicists, and other relevant staff using an MRI with a supplementary ELPS for patient alignment.<br /> (© 2026 The Author(s). Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine.)
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  Data: Magn Reson Med. 2008 Aug;60(2):320-9. (PMID: <searchLink fieldCode="PM" term="%2218666127%22">18666127)</searchLink><br />Magn Reson Imaging. 2013 Jun;31(5):669-75. (PMID: <searchLink fieldCode="PM" term="%2223290478%22">23290478)</searchLink><br />J Magn Reson Imaging. 2013 Jul;38(1):2-11. (PMID: <searchLink fieldCode="PM" term="%2223633246%22">23633246)</searchLink><br />Radiother Oncol. 2023 Aug;185:109717. (PMID: <searchLink fieldCode="PM" term="%2237211282%22">37211282)</searchLink><br />Radiology. 1989 Oct;173(1):265-7. (PMID: <searchLink fieldCode="PM" term="%222781018%22">2781018)</searchLink><br />HPB (Oxford). 2017 Aug;19(8):706-712. (PMID: <searchLink fieldCode="PM" term="%2228528267%22">28528267)</searchLink><br />Nat Methods. 2012 Jul;9(7):671-5. (PMID: <searchLink fieldCode="PM" term="%2222930834%22">22930834)</searchLink><br />Br J Radiol. 2018 May;91(1085):20170671. (PMID: <searchLink fieldCode="PM" term="%2229376736%22">29376736)</searchLink><br />Magn Reson Med. 2002 Jun;47(6):1202-10. (PMID: <searchLink fieldCode="PM" term="%2212111967%22">12111967)</searchLink><br />Magn Reson Med. 2024 Feb;91(2):741-759. (PMID: <searchLink fieldCode="PM" term="%2237814776%22">37814776)</searchLink><br />Magn Reson Med. 2021 Feb;85(2):734-747. (PMID: <searchLink fieldCode="PM" term="%2232783200%22">32783200)</searchLink><br />Magn Reson Imaging. 2012 Nov;30(9):1323-41. (PMID: <searchLink fieldCode="PM" term="%2222770690%22">22770690)</searchLink><br />Magn Reson Med. 2008 Oct;60(4):895-907. (PMID: <searchLink fieldCode="PM" term="%2218816810%22">18816810)</searchLink><br />J Clin Imaging Sci. 2024 Sep 05;14:33. (PMID: <searchLink fieldCode="PM" term="%2239371545%22">39371545)</searchLink><br />J Magn Reson Imaging. 2013 Aug;38(2):269-87. (PMID: <searchLink fieldCode="PM" term="%2223960007%22">23960007)</searchLink><br />Br J Radiol. 2015;88(1056):20150487. (PMID: <searchLink fieldCode="PM" term="%2226402216%22">26402216)</searchLink><br />J Appl Clin Med Phys. 2015 Mar 08;16(2):5201. (PMID: <searchLink fieldCode="PM" term="%2226103190%22">26103190)</searchLink><br />Radiother Oncol. 2023 Jun;183:109641. (PMID: <searchLink fieldCode="PM" term="%2236990394%22">36990394)</searchLink><br />J Appl Clin Med Phys. 2025 Jul;26(7):e70134. (PMID: <searchLink fieldCode="PM" term="%2240645191%22">40645191)</searchLink><br />Biometrics. 1989 Mar;45(1):255-68. (PMID: <searchLink fieldCode="PM" term="%222720055%22">2720055)</searchLink><br />Magn Reson Med. 2002 Jan;47(1):42-52. (PMID: <searchLink fieldCode="PM" term="%2211754441%22">11754441)</searchLink>
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              Text: 2026 Aug
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