Academic Journal

Validity of transcutaneous capnometry in prolonged use in a patient population with acute respiratory failure.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Validity of transcutaneous capnometry in prolonged use in a patient population with acute respiratory failure.
Συγγραφείς: Kächele M; Clinic for Internal Medicine I, University Hospital Ulm, Albert-Einstein-Allee 23, Ulm, 89081, Germany. Electronic address: martin.kaechele@uniklinik-ulm.de., Hasmüller M; Clinic for Internal Medicine I, University Hospital Ulm, Albert-Einstein-Allee 23, Ulm, 89081, Germany., Kalner A; Clinic for Internal Medicine I, University Hospital Ulm, Albert-Einstein-Allee 23, Ulm, 89081, Germany., Seufferlein T; Clinic for Internal Medicine I, University Hospital Ulm, Albert-Einstein-Allee 23, Ulm, 89081, Germany., Müller M; Clinic for Internal Medicine I, University Hospital Ulm, Albert-Einstein-Allee 23, Ulm, 89081, Germany; Western Allgaeu Hospital Wangen, Am Engelberg 29, Wangen im Allgäu, 88239, Germany.
Πηγή: Respiratory medicine [Respir Med] 2026 Sep; Vol. 261, pp. 109072. Date of Electronic Publication: 2026 Jul 31.
Τύπος έκδοσης: Journal Article; Validation Study
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: England NLM ID: 8908438 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3064 (Electronic) Linking ISSN: 09546111 NLM ISO Abbreviation: Respir Med Subsets: MEDLINE
Imprint Name(s): Publication: 2003- : Oxford : Elsevier
Original Publication: London : Baillière Tindall, in association with the British Thoracic Society, [c1989-
Ιατρικοί όροι (MeSH): Blood Gas Monitoring, Transcutaneous*/methods , Blood Gas Monitoring, Transcutaneous*/instrumentation , Respiratory Insufficiency*/blood , Respiratory Insufficiency*/diagnosis, Carbon Dioxide/blood ; Blood Gas Analysis/methods ; Monitoring, Physiologic/methods ; Humans ; Female ; Male ; Middle Aged ; Aged ; Acute Disease ; Reproducibility of Results ; Adult ; Critical Illness ; Aged, 80 and over ; Feasibility Studies
Περίληψη: Background: Transcutaneous capnometry is a widespread method for monitoring carbon dioxide in respiratory care. Studies on its use in emergency medicine, the sensors long-term stability its practicability in this setting are lacking. This study aimed to clarify whether transcutaneous capnometry is a valid and feasible method for monitoring critically ill patients.
Methods: 100 patients with acute respiratory failure were monitored simultaneously with arterial blood gas analysis (paCO2) and transcutaneous capnometry (tcpCO2), using Radiometer TCM5, at baseline (T1) and after a maximum of 12 h (T2) an analyzed regarding clinically acceptable concordance and interruptions.
Results: Ninety-three patients (176 paired samples of paCO2 and tcpCO2) were included in the analysis. We found a good correlation between pCO2 and tcpCO2 (r = 0.9706) at T1, which weakened at T2 (r = 0.7760). However, the difference in the concordance of the measured values at T1 and T2 was not significantly different (p = 0.0545). Significantly frequent deviations between T1 and T2 occurred in patients with circulatory impairment (p = 0.0039). 22.9% of all values were outside the clinically acceptable range, but with paCO2 underestimated by tcpCO2 in only 5 cases (2.8%). In all clinically relevant deviations, we found an underlying technical error which would have been found by a trained examiner.
Conclusions: Transcutaneous capnometry is a feasible method for monitoring CO2 trends. However, its successful application requires thorough knowledge of the analysis technique and potential sources of error. The validity of the method is limited in patients with significant circulatory dysregulation. Additionally, long-term use in clinical practice is often restricted by suboptimal patient conditions.
(Copyright © 2026 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Competing Interests: Declaration of competing interest All authors declare no conflicts of interest.
Contributed Indexing: Keywords: Acute respiratory failure; Capnometry; Hypercapnia; Transcutaneous carbon dioxide monitoring
Substance Nomenclature: 142M471B3J (Carbon Dioxide)
Entry Date(s): Date Created: 20260731 Date Completed: 20260812 Latest Revision: 20260812
Update Code: 20260813
DOI: 10.1016/j.rmed.2026.109072
PMID: 42537816
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:1532-3064
DOI:10.1016/j.rmed.2026.109072