Clinical and Sociodemographic Characteristics of Young People With Early Psychosis: Comparing Cannabis Users and Non-Users in a Specialized Early Intervention Setting.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος:	Clinical and Sociodemographic Characteristics of Young People With Early Psychosis: Comparing Cannabis Users and Non-Users in a Specialized Early Intervention Setting.
Συγγραφείς:	Willert A; Department of Psychiatry, Psychotherapy and Psychosomatics, Vivantes Klinikum Am Urban and Vivantes Klinikum Im Friedrichshain, Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité Campus Mitte, Charité Universitätsmedizin Berlin, Berlin, Germany., von Hardenberg L; Department of Psychiatry, Psychotherapy and Psychosomatics, Vivantes Klinikum Am Urban and Vivantes Klinikum Im Friedrichshain, Berlin, Germany., Holzner L; Department of Psychiatry, Psychotherapy and Psychosomatics, Vivantes Klinikum Am Urban and Vivantes Klinikum Im Friedrichshain, Berlin, Germany., Kallenbach M; Department of Psychiatry, Psychotherapy and Psychosomatics, Vivantes Klinikum Am Urban and Vivantes Klinikum Im Friedrichshain, Berlin, Germany., Reichert E; Department of Psychiatry, Psychotherapy and Psychosomatics, Vivantes Klinikum Am Urban and Vivantes Klinikum Im Friedrichshain, Berlin, Germany., Bechdolf A; Department of Psychiatry, Psychotherapy and Psychosomatics, Vivantes Klinikum Am Urban and Vivantes Klinikum Im Friedrichshain, Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité Campus Mitte, Charité Universitätsmedizin Berlin, Berlin, Germany.; Deutsches Zentrum für Psychische Gesundheit (DZPG), Berlin-Potsdam, Germany., Leopold K; Department of Psychiatry, Psychotherapy and Psychosomatics, Vivantes Klinikum Am Urban and Vivantes Klinikum Im Friedrichshain, Berlin, Germany.; Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
Πηγή:	Early intervention in psychiatry [Early Interv Psychiatry] 2026 Aug; Vol. 20 (8), pp. e70240.
Τύπος έκδοσης:	Journal Article; Comparative Study
Γλώσσα:	English
Στοιχεία περιοδικού:	Publisher: Wiley-Blackwell Country of Publication: Australia NLM ID: 101320027 Publication Model: Print Cited Medium: Internet ISSN: 1751-7893 (Electronic) Linking ISSN: 17517885 NLM ISO Abbreviation: Early Interv Psychiatry Subsets: MEDLINE
Imprint Name(s):	Original Publication: Carlton,VIC, Australia : Wiley-Blackwell
Ιατρικοί όροι (MeSH):	Psychotic Disorders/diagnosis , Psychotic Disorders/epidemiology , Psychotic Disorders/therapy , Psychotic Disorders/psychology , Marijuana Abuse/epidemiology , Psychoses, Substance-Induced/diagnosis , Psychoses, Substance-Induced/epidemiology , Psychoses, Substance-Induced/therapy , Early Medical Intervention*, Humans ; Female ; Male ; Retrospective Studies ; Adult ; Adolescent ; Young Adult
Περίληψη:	Background: Despite the high prevalence of comorbid cannabis use at first onset of psychotic symptoms, high transition rates from cannabis-induced psychosis to schizophreniform psychoses and bipolar disorder, and evidence of cannabis use as a risk factor in developing primary psychosis, only a few studies have addressed the difficulties in differential diagnosis focusing on the early stages of the disease. Aims: The present study is the first to date to examine clinical and sociodemographic characteristics of individuals with early psychosis, comparing cannabis-induced psychotic disorder (CIPD), non-substance-induced psychotic disorder with concurrent cannabis use (NSIPD+C), and non-substance-induced psychotic disorder (NSIPD). Method: A retrospective chart review of patients aged 18-35 with early psychosis who received inpatient treatment at FRITZ Early Intervention Center between December 2016 and September 2021 was conducted. Sociodemographic characteristics included age, biological sex, family history of psychiatric illness, migration background, living status, education/work status. Clinical characteristics included insight into illness, duration of untreated psychosis (DUP), social functioning, pathway to treatment, treatment motivation, treatment recommendation, and type of discharge. Results: Of 509 participants, 42.6% had a diagnosis of NSIPD, 33.3% of CIPD, 7% of NSIPD+C. NSIPD had a significantly longer treatment duration compared to CIPD, a higher treatment motivation, and a higher discharge in accordance with clinicians' recommendation compared to both CIPD and NSIPD+C. No significant group differences were found in sociodemographic characteristics, DUP, and functioning scores. Conclusions: The examined sociodemographic parameters as well as level of functioning and DUP do not aid in the differential diagnostic classification when cannabis use and psychotic symptoms occur simultaneously. The absence of differences in DUP across diagnoses may reflect the efficacy of low-threshold access provided by FRITZ and further supports the need for comprehensive implementation of early intervention services. (© 2026 The Author(s). Early Intervention in Psychiatry published by John Wiley & Sons Australia, Ltd.)
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Entry Date(s):	Date Created: 20260727 Date Completed: 20260727 Latest Revision: 20260818
Update Code:	20260818
PubMed Central ID:	PMC13403289
DOI:	10.1111/eip.70240
PMID:	42504862
Βάση Δεδομένων:	MEDLINE

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