Academic Journal
Transcriptomic insights into the antifungal efficacy of Bacillus velezensis-synthesized silver nanoparticles against toxigenic fusarium verticillioides.
| Τίτλος: | Transcriptomic insights into the antifungal efficacy of Bacillus velezensis-synthesized silver nanoparticles against toxigenic fusarium verticillioides. |
|---|---|
| Συγγραφείς: | Ishfaq S; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences/Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs, Beijing 100193, PR China., Gai X; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences/Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs, Beijing 100193, PR China; Yunnan Academy of Tobacco Agricultural Sciences, Kunming 650031, PR China., Liang X; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences/Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs, Beijing 100193, PR China., Ding Y; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences/Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs, Beijing 100193, PR China., Wang R; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences/Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs, Beijing 100193, PR China., Anjum A; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences/Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs, Beijing 100193, PR China., Cai Y; Qujing Tobacco Company of Yunnan, Qujing 655000, PR China., Rafiq A; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences/Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs, Beijing 100193, PR China., Guo W; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences/Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs, Beijing 100193, PR China. Electronic address: guowei01@caas.cn. |
| Πηγή: | Pesticide biochemistry and physiology [Pestic Biochem Physiol] 2026 Aug; Vol. 222, pp. 107233. Date of Electronic Publication: 2026 Jun 29. |
| Τύπος έκδοσης: | Evaluation Study; Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Academic Press Country of Publication: United States NLM ID: 1301573 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9939 (Electronic) Linking ISSN: 00483575 NLM ISO Abbreviation: Pestic Biochem Physiol Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: New York Ny : Academic Press |
| Ιατρικοί όροι (MeSH): | Antifungal Agents*/metabolism , Antifungal Agents*/pharmacology , Bacillus*/metabolism , Pest Control, Biological*/methods , Fusarium*/drug effects , Metal Nanoparticles* , Silver*, Plant Diseases/prevention & control ; Silver Nitrate/metabolism ; Zea mays/microbiology ; Green Chemistry Technology ; Microbial Sensitivity Tests |
| Περίληψη: | The escalating demand for sustainable agricultural practices has prompted the exploration of nanotechnology-based solutions for plant protection. In this study, silver nanoparticles (AgNPs) were biosynthesized using Bacillus velezensis IFST-221, and their antifungal efficacy against Fusarium verticillioides, a pathogenic fungus responsible for ear and stalk rot in maize, was evaluated. The green synthesis approach employed in this work offers an eco-friendly and biocompatible method for producing AgNPs, making them suitable for agricultural applications. In vitro antifungal assays demonstrated a significant inhibitory effect of the AgNPs on F. verticillioides, accompanied by a reduction in fungal-induced oxidative stress in maize. Biochemical analyses revealed a marked enhancement in the activities of key antioxidant enzymes, including peroxidase (POD), catalase (CAT), and superoxide dismutase (SOD), along with a substantial decrease in oxidative stress markers, such as reactive oxygen species (ROS) and malondialdehyde (MDA). Transcriptomic analysis of F. verticillioides exposed to AgNPs highlighted significant changes in gene expression, particularly in pathways related to metabolism, membrane integrity, and ion transport. Functional enrichment using Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases identified critical biological processes and molecular functions involved in the antifungal action of AgNPs. These findings underscore the potential of biosynthesized AgNPs as effective nano-microbicides for the control of fungal pathogens and stress mitigation in crops, presenting a promising strategy for sustainable agricultural practices. (Copyright © 2026 Elsevier Inc. All rights reserved.) |
| Competing Interests: | Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. |
| Contributed Indexing: | Keywords: Antifungal activity; Bacillus velezensis; Fusarium verticillioides; Green synthesis of silver nanoparticles |
| Substance Nomenclature: | 0 (Antifungal Agents) 3M4G523W1G (Silver) 95IT3W8JZE (Silver Nitrate) |
| SCR Organism: | Bacillus velezensis; Fusarium verticillioides |
| Entry Date(s): | Date Created: 20260723 Date Completed: 20260729 Latest Revision: 20260729 |
| Update Code: | 20260729 |
| DOI: | 10.1016/j.pestbp.2026.107233 |
| PMID: | 42493044 |
| Βάση Δεδομένων: | MEDLINE |
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