Academic Journal

Test-bench experimental validation of pressure accuracy in a mechanical threshold device for inspiratory muscle training: The threshold IMT® case.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Test-bench experimental validation of pressure accuracy in a mechanical threshold device for inspiratory muscle training: The threshold IMT® case.
Συγγραφείς: Foschiani M; Department of Medicine, University of Udine, Udine, Italy., Bortolotti E; Advantech TIME Srl, Udine, Italy., Chiavone A; Advantech TIME Srl, Udine, Italy., Salvitti S; Department of Medicine, University of Udine, Udine, Italy; Unit of Cardiorespiratory Physiotherapy, Azienda Sanitaria Universitaria Friuli Centrale (ASUFC), Udine, Italy. Electronic address: simone.salvitti@uniud.it.
Πηγή: Respiratory medicine [Respir Med] 2026 Sep; Vol. 261, pp. 109025. Date of Electronic Publication: 2026 Jul 11.
Τύπος έκδοσης: Journal Article; Validation Study
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: England NLM ID: 8908438 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3064 (Electronic) Linking ISSN: 09546111 NLM ISO Abbreviation: Respir Med Subsets: MEDLINE
Imprint Name(s): Publication: 2003- : Oxford : Elsevier
Original Publication: London : Baillière Tindall, in association with the British Thoracic Society, [c1989-
Ιατρικοί όροι (MeSH): Respiratory Muscles*/physiology , Inhalation*/physiology , Breathing Exercises*/instrumentation , Breathing Exercises*/methods, Humans ; Reproducibility of Results ; Pressure ; Equipment Design ; Calibration
Περίληψη: Inspiratory muscle training (IMT) is widely used in rehabilitation, yet the accuracy of mechanical threshold devices has been only partially characterised. The aim of this study was to evaluate the validity and stability of the pressure delivered by the Threshold IMT® device (Philips Respironics) using independent calibrated instrumentation, with the measurement chain itself validated against a weighted-plunger reference method. Three units were tested on a bench equipped with a calibrated differential pressure transducer (YOKOGAWA EJA110E; full-scale (FS) error ≤0.055%), an ISO 5167-3-referenced differential flow meter (uncertainty <5%), and an industrial fan. Five measurements per nominal pressure level (9, 25, and 41 cmH2O) were collected for each device across a range of inspiratory flow rates. The pressure reported by the bench corresponds to the total differential developed at the patient side, i.e. the load the inspiratory muscles must overcome at the mouth. A two-way ANOVA was used to assess precision and inter-device reproducibility. The measurement chain reproduced the weighted-plunger reference pressures to within 2.5%, confirming its accuracy. The patient-side pressures were systematically lower than the nominal scale values at all three levels, corresponding to approximately 40-50% of the set value (linear regression slope = 0.49; R2 ≈ 0.99). Reproducibility was good (no significant device main effect: F [2,36] = 0.24; p = 0.79), indicating a design-inherent characteristic rather than a manufacturing artefact. The pressure-flow relationship followed a logarithmic curve for each device and threshold level. For the device tested, the nominal scale value did not correspond to the pressure measured at the patient side. These findings have implications for how Threshold IMT® settings are interpreted when designing and reporting IMT protocols.
(Copyright © 2026 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Competing Interests: Declaration of competing interest Employment: No author is employed by the manufacturer of the device under test (Koninklijke Philips N.V.) or by any entity with a commercial interest in the outcomes of this study. Advantech TIME Srl is a company specializing in fluid dynamics, thermodynamics, and acoustics, with an in-house testing laboratory. The company provided the test bench infrastructure for this study. It has no commercial relationship with Koninklijke Philips N.V. and no financial interest in the outcomes of the pressure accuracy assessment reported herein. Consultancies: No author has served as a consultant for any organisation with a financial interest in the subject matter of this manuscript. Stock ownership: No author holds stocks, shares, or equity in any company with a financial interest in the subject matter of this manuscript. Honoraria: No author has received honoraria related to the subject matter of this manuscript. Paid expert testimony: No author has provided paid expert testimony related to the subject matter of this manuscript. Patent applications or registrations: No author holds or has applied for patents related to the subject matter of this manuscript. Grants or any other funding: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Affiliation with the journal: No author serves or has served as an Editor, Associate Editor, or Advisory Board Member of Respiratory Medicine.
Contributed Indexing: Keywords: Device validation; Inspiratory muscle training; Pressure measurement; Respiratory rehabilitation; Threshold IMT; Threshold pressure device
Entry Date(s): Date Created: 20260711 Date Completed: 20260812 Latest Revision: 20260812
Update Code: 20260813
DOI: 10.1016/j.rmed.2026.109025
PMID: 42435916
Βάση Δεδομένων: MEDLINE