Λεπτομέρειες βιβλιογραφικής εγγραφής
| Τίτλος: |
[Associations between central auditory processing function and attentional function in age-related hearing loss]. |
| Συγγραφείς: |
Zhu M; Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China., Sun W; Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China., Qiao YF; Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China., Liu QY; Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China., Shen H; Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China., Shang YY; Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China. |
| Πηγή: |
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery [Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi] 2026 Jun 07; Vol. 61 (6), pp. 609-616. |
| Τύπος έκδοσης: |
English Abstract; Journal Article |
| Γλώσσα: |
Chinese |
| Στοιχεία περιοδικού: |
Publisher: Zhonghua yi xue hui za zhi she Country of Publication: China NLM ID: 101247574 Publication Model: Print Cited Medium: Print ISSN: 1673-0860 (Print) Linking ISSN: 16730860 NLM ISO Abbreviation: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi Subsets: MEDLINE |
| Imprint Name(s): |
Original Publication: Beijing : Zhonghua yi xue hui za zhi she, 2005- |
| Ιατρικοί όροι (MeSH): |
Presbycusis*/physiopathology , Attention* , Auditory Perception*, Humans ; Middle Aged ; Female ; Aged ; Male ; Audiometry, Pure-Tone ; Auditory Acuity ; Case-Control Studies ; Auditory Threshold |
| Περίληψη: |
Objective: To investigate the relationships between peripheral auditory function, central auditory processing, and attentional function in individuals with age-related hearing loss (ARHL), thereby providing scientific evidence for the clinical assessment and intervention of ARHL. Methods: A total of 32 individuals with ARHL who were recruited from Peking Union Medical College Hospital between September 2020 and March 2024 were enrolled, including 12 males and 20 females, aged 60-73 years (mean age: 66.1 years). Additionally, 32 age-matched individuals with normal hearing were recruited as the control group, including 14 males and 18 females, aged 60-70 years (mean age: 65.4 years). Peripheral auditory function was assessed using pure-tone audiometry (PTA). Central auditory processing was evaluated using the speech-in-noise (SIN) test and the gaps-in-noise (GIN) test. Attentional function was assessed with the digit vigilance test (DVT). Statistical analyses were performed using SPSS 27.0 software. Results: Compared with the control group, individuals with ARHL exhibited significantly prolonged DVT reaction time (RT), indicating poorer performance on the attention task [ARHL group: (210.2±43.1) s; control group: (189.3±37.3) s; t=2.068, P=0.043]. In the ARHL group, SIN threshold was significantly positively correlated with DVT RT (pr=0.502, P=0.005). Among all participants, both SIN and GIN thresholds were significantly positively correlated with DVT RT (SIN: pr=0.691, P<0.001; GIN: pr=0.349, P=0.006), whereas the PTA threshold showed only a marginal correlation with DVT RT (pr=0.229, P=0.075). Multiple linear regression analysis revealed that the SIN threshold was the only auditory measure independently associated with DVT RT (β=9.673, 95%CI: 3.611-15.734, P=0.002). Conclusions: Individuals with ARHL demonstrate prolonged RT on attention-related tasks, suggesting a potential decline in attentional processing speed. The association between central auditory processing ability and attentional processing speed is substantially stronger than that between peripheral auditory function and attentional processing speed. These findings suggest that central auditory processing function may have potential value in the investigation and assessment of cognitive function in older adults. |
| Competing Interests: |
所有作者声明无利益冲突 |
| Grant Information: |
32371051, 82171156 National Natural Science Foundation of China; UBJ10135 Peking Union Medical College Hospital Talent Cultivation Program (Category C) |
| Contributed Indexing: |
Local Abstract: [Publisher, Chinese] 目的： 探讨年龄相关听力损失（age-related hearing loss，ARHL）患者外周听觉功能及中枢听觉处理功能与注意功能之间的关系，为ARHL的临床评估及干预提供科学依据。 方法： 研究对象为2020年9月至2024年3月就诊于北京协和医院的32例ARHL患者，其中男12例，女20例，年龄范围60~73岁，平均年龄66.1岁。另外招募32名听力正常人作为对照组，其中男14例，女18例，年龄范围60~70岁，平均年龄65.4岁。受试者外周听觉功能通过纯音测听进行评估，中枢听觉处理功能通过噪声下言语识别（speech-in-noise，SIN）及噪声间隔（gaps-in-noise，GIN）测试加以评估。通过数字警醒测试（digit vigilance test，DVT）评估受试者注意功能。采用SPSS 27.0软件完成统计分析。 结果： 与对照组相比，ARHL患者的DVT反应时间显著延长，差异具有统计学意义［ARHL组：（210.2±43.1）s；对照组：（189.3±37.3）s；t=2.068，P=0.043］。SIN阈值与DVT反应时间在ARHL组中呈显著正相关（pr=0.502，P=0.005）。在所有受试者中，SIN阈值和GIN阈值均与DVT反应时间显著相关（SIN：pr=0.691，P<0.001；GIN：pr=0.349，P=0.006），而纯音平均听阈与DVT反应时间仅呈边缘相关（pr=0.229，P=0.075）。多元线性回归分析结果显示，SIN阈值是唯一与DVT反应时间独立相关的听觉评估指标（β=9.673，95%CI=3.611~15.734，P=0.002）。 结论： ARHL患者注意相关任务反应时间延长，提示注意加工速度可能受损。老年人中枢听觉处理能力与注意加工速度的相关性显著强于外周听觉能力。中枢听觉处理功能在老年人认知功能研究及评估中可能具有一定的潜在价值。. |
| Entry Date(s): |
Date Created: 20260708 Date Completed: 20260708 Latest Revision: 20260708 |
| Update Code: |
20260709 |
| DOI: |
10.3760/cma.j.cn115330-20250729-00405 |
| PMID: |
42420022 |
| Βάση Δεδομένων: |
MEDLINE |