Academic Journal
Response times from gap detection threshold testing relate to cognitive processing speed in young adults.
| Τίτλος: | Response times from gap detection threshold testing relate to cognitive processing speed in young adults. |
|---|---|
| Συγγραφείς: | Niemczak C; Dartmouth-Hitchcock Medical Center, Department of Medicine, Lebanon, NH, USA; Geisel School of Medicine at Dartmouth, Department of Quantitative Biomedical Sciences, Hanover, NH, USA; Geisel School of Medicine at Dartmouth, Space Medicine Innovation Lab, Lebanon, NH, USA. Electronic address: Christopher.e.niemczak@dartmouth.edu., Ealer C; Geisel School of Medicine at Dartmouth, Space Medicine Innovation Lab, Lebanon, NH, USA., Froese K; Geisel School of Medicine at Dartmouth, Space Medicine Innovation Lab, Lebanon, NH, USA; University of Arizona, Department of Speech, Language, and Hearing Sciences, Tucson, AZ, USA., Fellows A; Geisel School of Medicine at Dartmouth, Space Medicine Innovation Lab, Lebanon, NH, USA., Leigh S; Geisel School of Medicine at Dartmouth, Space Medicine Innovation Lab, Lebanon, NH, USA., Mirza S; Geisel School of Medicine at Dartmouth, Department of Quantitative Biomedical Sciences, Hanover, NH, USA., Gui J; Geisel School of Medicine at Dartmouth, Department of Quantitative Biomedical Sciences, Hanover, NH, USA., Magohe A; Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania., Massawe E; Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania., Musiek F; University of Arizona, Department of Speech, Language, and Hearing Sciences, Tucson, AZ, USA., Buckey J; Dartmouth-Hitchcock Medical Center, Department of Medicine, Lebanon, NH, USA; Geisel School of Medicine at Dartmouth, Department of Quantitative Biomedical Sciences, Hanover, NH, USA; Geisel School of Medicine at Dartmouth, Space Medicine Innovation Lab, Lebanon, NH, USA. |
| Πηγή: | Neuroscience [Neuroscience] 2026 Sep 11; Vol. 611, pp. 251-260. Date of Electronic Publication: 2026 Jul 03. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7544 (Electronic) Linking ISSN: 03064522 NLM ISO Abbreviation: Neuroscience Subsets: MEDLINE |
| Imprint Name(s): | Publication: [New York?] : Elsevier Science Original Publication: Oxford, Elmsford, N. Y., Pergamon Press |
| Ιατρικοί όροι (MeSH): | Processing Speed*/physiology , Reaction Time*/physiology , Auditory Perception*/physiology , Cognition*/physiology , Auditory Threshold*/physiology, HIV Infections/psychology ; HIV Infections/physiopathology ; Humans ; Female ; Adult ; Male ; Young Adult ; Adolescent ; Middle Aged ; Neuropsychological Tests ; Acoustic Stimulation ; Prospective Studies |
| Περίληψη: | Objective: In addition to a gap detection threshold, an auditory gap detection task also provides information on response time. This study investigated the association of response time from an adaptive gap detection task with two validated measures of cognitive processing speed as well as scores from a cognitive screener, while accounting for the effects of age, peripheral hearing ability, and HIV status. Design: Participants (age 17-45 years) were from a prospective cohort study in Dar es Salaam, Tanzania with normal hearing ability and no reported neurological diseases. The final sample included 283 unique subjects (158 living with HIV, 125 without HIV) matched on age and sex. Multiple linear regression models were employed to assess the relationship between gap response time and cognitive processing speed scores from the Tests of Variables of Attention, Cogstate test battery, and Montreal Cognitive Assessment. Results: Regression analysis showed significant relationships between gap response time and all processing speed scores, except one. Age showed varying degrees of association with different processing speed measures, but peripheral hearing ability did not show any significant relationship with speed measures. Conclusions: This study identifies a link between cognitive processing speed and gap detection response times. With further validation, gap detection response times could emerge as a straightforward yet informative measure of cognitive processing speed and would expand the clinical usefulness of the gap test. In the audiology clinic, this measure may hold promise as a tool for detecting and monitoring cognitive decline. (Copyright © 2026 The Authors. Published by Elsevier Inc. All rights reserved.) |
| Contributed Indexing: | Keywords: Cognitive processing speed; Gap detection; HIV; Response time; Temporal auditory processing |
| Entry Date(s): | Date Created: 20260703 Date Completed: 20260730 Latest Revision: 20260730 |
| Update Code: | 20260731 |
| DOI: | 10.1016/j.neuroscience.2026.07.010 |
| PMID: | 42398888 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1873-7544 |
|---|---|
| DOI: | 10.1016/j.neuroscience.2026.07.010 |