Academic Journal
An update on the Tenebrio molitor immune system.
| Τίτλος: | An update on the Tenebrio molitor immune system. |
|---|---|
| Συγγραφείς: | Ramírez-Sotelo U; Departamento de Biología, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Noria Alta s/n, 36050, Guanajuato, Gto, Mexico., Mora-Montes HM; Departamento de Biología, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Noria Alta s/n, 36050, Guanajuato, Gto, Mexico. Electronic address: hmora@ugto.mx. |
| Πηγή: | Journal of invertebrate pathology [J Invertebr Pathol] 2026 Sep; Vol. 218, pp. 108689. Date of Electronic Publication: 2026 Jun 27. |
| Τύπος έκδοσης: | Journal Article; Review |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Academic Press Country of Publication: United States NLM ID: 0014067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0805 (Electronic) Linking ISSN: 00222011 NLM ISO Abbreviation: J Invertebr Pathol Subsets: MEDLINE |
| Imprint Name(s): | Publication: New York, NY : Academic Press Original Publication: New York. |
| Ιατρικοί όροι (MeSH): | Tenebrio*/immunology , Tenebrio*/microbiology , Immunity, Innate*, Hemocytes/immunology ; Animals ; Innate Immunity Recognition |
| Περίληψη: | Infections caused by pathogenic microorganisms represent a crucial challenge for the host's health and well-being, since they are a threat to its survival. During the species evolution, organisms developed a protective system against their microscopic disease-causing adversaries, which is a notable and highly valuable trait in the adaptation of living beings. The immune response is responsible for self- and non-self-recognition, an elemental step in establishing protective mechanisms. In invertebrates, innate immunity orchestrates the attack against pathogens. Insect immunity is composed of cellular responses mediated by hemocytes, as well as humoral effectors, which are soluble molecules with high antimicrobial potential. Notably, many of these components have a high degree of structural and functional similarity to mammalian immune effectors. Humoral effectors and hemocytes act synergistically for the recognition and control of bacteria, fungi, viruses, and parasites. The activation of signaling pathways is the first step in pathogen recognition, and in insects, both the Toll and immune deficiency pathways are the main ones that trigger effector responses, including antimicrobial peptides, opsonins, lysozymes, and metalloproteinase inhibitors, among others. Here, we summarize the main findings on Tenebrio molitor immunity and highlight relevant gaps in current knowledge of this beetle's biology. (Copyright © 2026. Published by Elsevier Inc.) |
| Competing Interests: | Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. |
| Contributed Indexing: | Keywords: Antimicrobial peptides; Fungus-insect interaction; Hemocyte; Innate immunity; Insect-bacteria interaction; Toll pathway |
| Entry Date(s): | Date Created: 20260627 Date Completed: 20260717 Latest Revision: 20260717 |
| Update Code: | 20260718 |
| DOI: | 10.1016/j.jip.2026.108689 |
| PMID: | 42364903 |
| Βάση Δεδομένων: | MEDLINE |
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