Academic Journal
Προβολή σε EDS

Harnessing veterinary nanomedicine: A One Health perspective.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Harnessing veterinary nanomedicine: A One Health perspective.
Συγγραφείς: Cillari R; Department of Biological Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Via Archirafi 32, 90123 Palermo, Italy., Mauro N; Department of Biological Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Via Archirafi 32, 90123 Palermo, Italy. Electronic address: nicolo.mauro@unipa.it.
Πηγή: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2026 Sep 10; Vol. 397, pp. 115139. Date of Electronic Publication: 2026 Jun 27.
Τύπος έκδοσης: Journal Article; Review; Research Support, Non-U.S. Gov't
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE
Imprint Name(s): Original Publication: Amsterdam : Elsevier Science Publishers, 1984-
Ιατρικοί όροι (MeSH): Nanomedicine*/methods , Veterinary Medicine*/methods , One Health*, Animals ; Drug Delivery Systems ; Humans
Περίληψη: Nanomedicine exploits the unique physicochemical properties of nanomaterials to enable advanced diagnostic and therapeutic strategies. In veterinary medicine, nanotechnology is rapidly emerging as a transformative platform across companion animals, livestock, and exotic species, with direct implications for animal welfare, productivity, and the One Health framework. Although several reviews have addressed specific aspects of nanotechnology in animal health, the field is expanding rapidly, generating new technological developments and translational insights that remain dispersed across disciplines. Consequently, an updated integrative synthesis is needed to contextualize recent advances and define the evolving role of nanomedicine in veterinary and comparative biomedical research. Nanomedicines enhance drug delivery, vaccine efficacy, diagnostics, and nutrition by improving the bioavailability, targeting capability, and safety profiles of active compounds, while also offering innovative solutions to challenges such as antimicrobial resistance and neoplastic diseases. Importantly, veterinary nanomedicine occupies a dual role: it delivers tangible clinical benefits to animals and serves as a critical translational bridge, generating preclinical insights relevant to human health. This review provides an updated overview of the current state-of-the-art in veterinary nanomedicine, highlighting applications in diagnostics, drug and gene delivery, nanovaccines, and nutrition, alongside emerging smart nano-enabled technologies. Particular emphasis is placed on integrating advances reported across different sectors, underlining opportunities and limitations. We also critically examine safety, regulatory, and ethical considerations, analyzing species-specific toxicology, environmental fate, food-chain safety, and evolving regulatory outlines. Future perspectives are discussed, emphasizing the integration of nanotechnology with One Health-driven translational research to support the responsible and impactful advancement of veterinary nanomedicine.
(Copyright © 2026. Published by Elsevier B.V.)
Contributed Indexing: Keywords: Drug delivery; Nanomedicine; Nanotechnology; One Health; Veterinary precision medicine
Entry Date(s): Date Created: 20260627 Date Completed: 20260826 Latest Revision: 20260910
Update Code: 20260910
DOI: 10.1016/j.jconrel.2026.115139
PMID: 42364700
Βάση Δεδομένων: MEDLINE
FullText Text:
  Availability: 0
CustomLinks:
  – Url: https://www.doi.org/10.1016/j.jconrel.2026.115139?
    Name: ScienceDirect (all content) (s7799221)
    Category: fullText
    Text: View record from ScienceDirect
    MouseOverText: View record from ScienceDirect
  – Url: https://resolver.ebsco.com/c/fiv2js/result?sid=EBSCO:cmedm&genre=article&issn=18734995&ISBN=&volume=397&issue=&date=20260910&spage=115139&pages=115139&title=Journal of controlled release : official journal of the Controlled Release Society&atitle=Harnessing%20veterinary%20nanomedicine%3A%20A%20One%20Health%20perspective.&aulast=Cillari%20R&id=DOI:10.1016/j.jconrel.2026.115139
    Name: Full Text Finder (for New FTF UI) (ns324271)
    Category: fullText
    Text: Full Text Finder
    MouseOverText: Full Text Finder
Header DbId: cmedm
DbLabel: MEDLINE
An: 42364700
AccessLevel: 3
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Harnessing veterinary nanomedicine: A One Health perspective.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Cillari+R%22">Cillari R</searchLink>; Department of Biological Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Via Archirafi 32, 90123 Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Mauro+N%22">Mauro N</searchLink>; Department of Biological Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Via Archirafi 32, 90123 Palermo, Italy. Electronic address: nicolo.mauro@unipa.it.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%228607908%22">Journal of controlled release : official journal of the Controlled Release Society</searchLink> [J Control Release] 2026 Sep 10; Vol. 397, pp. 115139. <i>Date of Electronic Publication: </i>2026 Jun 27.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Review; Research Support, Non-U.S. Gov't
– Name: Language
  Label: Language
  Group: Lang
  Data: English
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Publishers%22">Elsevier Science Publishers </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8607908 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-4995 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201683659%22">01683659 </searchLink><i>NLM ISO Abbreviation: </i>J Control Release <i>Subsets: </i>MEDLINE
– Name: PublisherInfo
  Label: Imprint Name(s)
  Group: PubInfo
  Data: <i>Original Publication</i>: Amsterdam : Elsevier Science Publishers, 1984-
– Name: SubjectMESH
  Label: MeSH Terms
  Group: Su
  Data: <searchLink fieldCode="MM" term="%22Nanomedicine%22">Nanomedicine*</searchLink>/<searchLink fieldCode="MM" term="%22Nanomedicine+methods%22">methods</searchLink> <br /><searchLink fieldCode="MM" term="%22Veterinary+Medicine%22">Veterinary Medicine*</searchLink>/<searchLink fieldCode="MM" term="%22Veterinary+Medicine+methods%22">methods</searchLink> <br /><searchLink fieldCode="MM" term="%22One+Health%22">One Health*</searchLink><br /><searchLink fieldCode="MH" term="%22Animals%22">Animals</searchLink> ; <searchLink fieldCode="MH" term="%22Drug+Delivery+Systems%22">Drug Delivery Systems</searchLink> ; <searchLink fieldCode="MH" term="%22Humans%22">Humans</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Nanomedicine exploits the unique physicochemical properties of nanomaterials to enable advanced diagnostic and therapeutic strategies. In veterinary medicine, nanotechnology is rapidly emerging as a transformative platform across companion animals, livestock, and exotic species, with direct implications for animal welfare, productivity, and the One Health framework. Although several reviews have addressed specific aspects of nanotechnology in animal health, the field is expanding rapidly, generating new technological developments and translational insights that remain dispersed across disciplines. Consequently, an updated integrative synthesis is needed to contextualize recent advances and define the evolving role of nanomedicine in veterinary and comparative biomedical research. Nanomedicines enhance drug delivery, vaccine efficacy, diagnostics, and nutrition by improving the bioavailability, targeting capability, and safety profiles of active compounds, while also offering innovative solutions to challenges such as antimicrobial resistance and neoplastic diseases. Importantly, veterinary nanomedicine occupies a dual role: it delivers tangible clinical benefits to animals and serves as a critical translational bridge, generating preclinical insights relevant to human health. This review provides an updated overview of the current state-of-the-art in veterinary nanomedicine, highlighting applications in diagnostics, drug and gene delivery, nanovaccines, and nutrition, alongside emerging smart nano-enabled technologies. Particular emphasis is placed on integrating advances reported across different sectors, underlining opportunities and limitations. We also critically examine safety, regulatory, and ethical considerations, analyzing species-specific toxicology, environmental fate, food-chain safety, and evolving regulatory outlines. Future perspectives are discussed, emphasizing the integration of nanotechnology with One Health-driven translational research to support the responsible and impactful advancement of veterinary nanomedicine.<br /> (Copyright © 2026. Published by Elsevier B.V.)
– Name: SubjectMinor
  Label: Contributed Indexing
  Group:
  Data: <i>Keywords: </i>Drug delivery; Nanomedicine; Nanotechnology; One Health; Veterinary precision medicine
– Name: DateEntry
  Label: Entry Date(s)
  Group: Date
  Data: <i>Date Created: </i>20260627 <i>Date Completed: </i>20260826 <i>Latest Revision: </i>20260910
– Name: DateUpdate
  Label: Update Code
  Group: Date
  Data: 20260910
– Name: DOI
  Label: DOI
  Group: ID
  Data: 10.1016/j.jconrel.2026.115139
– Name: AN
  Label: PMID
  Group: ID
  Data: 42364700
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=cmedm&AN=42364700
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.jconrel.2026.115139
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 115139
    Subjects:
      – SubjectFull: Animals
        Type: general
      – SubjectFull: Drug Delivery Systems
        Type: general
      – SubjectFull: Humans
        Type: general
      – SubjectFull: Nanomedicine methods
        Type: general
      – SubjectFull: Veterinary Medicine methods
        Type: general
      – SubjectFull: One Health
        Type: general
    Titles:
      – TitleFull: Harnessing veterinary nanomedicine: A One Health perspective.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Cillari R
      – PersonEntity:
          Name:
            NameFull: Mauro N
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 10
              M: 09
              Text: 2026 Sep 10
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1873-4995
          Numbering:
            – Type: volume
              Value: 397
          Titles:
            – TitleFull: Journal of controlled release : official journal of the Controlled Release Society
              Type: main
ResultId 1