Academic Journal
Structural property and bioactivity evaluation of reactive oxygen species hydrogels loaded with different polyphenols.
| Τίτλος: | Structural property and bioactivity evaluation of reactive oxygen species hydrogels loaded with different polyphenols. |
|---|---|
| Συγγραφείς: | Fan Y; Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650550, China; Yunnan International Joint Laboratory of Green Food Processing, Kunming 650500, China., Duan S; Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650550, China; Yunnan International Joint Laboratory of Green Food Processing, Kunming 650500, China., Zhang H; Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650550, China; Yunnan International Joint Laboratory of Green Food Processing, Kunming 650500, China., Li C; Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650550, China; Yunnan International Joint Laboratory of Green Food Processing, Kunming 650500, China., Cheng G; Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650550, China; Yunnan International Joint Laboratory of Green Food Processing, Kunming 650500, China., Cui T; Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650550, China; Yunnan International Joint Laboratory of Green Food Processing, Kunming 650500, China. Electronic address: cuitianqi0906@163.com. |
| Πηγή: | Food chemistry [Food Chem] 2026 Sep 15; Vol. 523, pp. 150119. Date of Electronic Publication: 2026 Jun 22. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE |
| Imprint Name(s): | Publication: Barking : Elsevier Applied Science Publishers Original Publication: Barking, Eng., Applied Science Publishers. |
| Ιατρικοί όροι (MeSH): | Polyphenols*/chemistry , Polyphenols*/pharmacology , Hydrogels*/chemistry , Anti-Bacterial Agents*/chemistry , Anti-Bacterial Agents*/pharmacology , Reactive Oxygen Species*/chemistry , Reactive Oxygen Species*/pharmacology , Antioxidants*/chemistry , Antioxidants*/pharmacology , Drug Carriers*/chemistry, Staphylococcus aureus/drug effects ; Staphylococcus aureus/growth & development |
| Περίληψη: | A multifunctional hydrogel system was constructed using gelatin, oxidized sodium alginate, and thioketal via a Schiff base reaction. Three polyphenols with distinct chemical structures, 6'-O-Caffeoylarbutin (CA), gallic acid (GA), and tannic acid (TA), were loaded into the hydrogel. The physicochemical properties and bioactivities of hydrogels were systematically investigated. Results showed that the GA-loaded hydrogel exhibited a uniform honeycomb-like porous structure and displayed the optimal antioxidant activity, with an ABTS radical scavenging rate as high as 96.51%. The CA-loaded hydrogel possessed the best mechanical properties. All three hydrogels formed inhibition zones against Staphylococcus aureus and displayed favorable biocompatibility. Thioketal endowed the hydrogel with the ability to release on demand in response to reactive oxygen species, and significantly enhances clearance capacity for O₂- and ·OH of hydrogels. All polyphenol-loaded hydrogels exhibited radical scavenging rates exceeding 63%. This dual-network hydrogel can serve as an ideal carrier to achieve stable loading, controlled release of active polyphenols, showing potential applications in delivery systems. (Copyright © 2026. Published by Elsevier Ltd.) |
| Competing Interests: | Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. |
| Contributed Indexing: | Keywords: Antibacterial; Antioxidant; Multifunctional hydrogel; Polyphenols; ROS response |
| Substance Nomenclature: | 0 (Polyphenols) 0 (Hydrogels) 0 (Anti-Bacterial Agents) 0 (Reactive Oxygen Species) 0 (Antioxidants) 0 (Drug Carriers) |
| Entry Date(s): | Date Created: 20260626 Date Completed: 20260807 Latest Revision: 20260807 |
| Update Code: | 20260807 |
| DOI: | 10.1016/j.foodchem.2026.150119 |
| PMID: | 42361566 |
| Βάση Δεδομένων: | MEDLINE |
καταχωρήστε σχόλιο πρώτοι!