Academic Journal
An Epidemic of Complexity: Polysubstance Use Fatal Overdose Typologies Across Cook County, Illinois, Neighborhoods, 2017‒2022.
| Τίτλος: | An Epidemic of Complexity: Polysubstance Use Fatal Overdose Typologies Across Cook County, Illinois, Neighborhoods, 2017‒2022. |
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| Συγγραφείς: | Cadet K; Kechna Cadet is with Columbia University Vagelos College of Physicians and Surgeons and Mailman School of Public Health, New York, NY. Silvia S. Martins is with Columbia Mailman School of Public Health. Elizabeth D. Nesoff is with the University of Pennsylvania Perelman School of Medicine, Philadelphia., Martins SS; Kechna Cadet is with Columbia University Vagelos College of Physicians and Surgeons and Mailman School of Public Health, New York, NY. Silvia S. Martins is with Columbia Mailman School of Public Health. Elizabeth D. Nesoff is with the University of Pennsylvania Perelman School of Medicine, Philadelphia., Nesoff ED; Kechna Cadet is with Columbia University Vagelos College of Physicians and Surgeons and Mailman School of Public Health, New York, NY. Silvia S. Martins is with Columbia Mailman School of Public Health. Elizabeth D. Nesoff is with the University of Pennsylvania Perelman School of Medicine, Philadelphia. |
| Πηγή: | American journal of public health [Am J Public Health] 2026 Aug; Vol. 116 (8), pp. 1210-1219. Date of Electronic Publication: 2026 Jun 18. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: American Public Health Association Country of Publication: United States NLM ID: 1254074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1541-0048 (Electronic) Linking ISSN: 00900036 NLM ISO Abbreviation: Am J Public Health Subsets: MEDLINE |
| Imprint Name(s): | Publication: Washington, DC : American Public Health Association Original Publication: New York [etc.] |
| Ιατρικοί όροι (MeSH): | Drug Overdose*/mortality , Drug Overdose*/epidemiology , Substance-Related Disorders*/epidemiology , Substance-Related Disorders*/mortality , Residence Characteristics*/statistics & numerical data, Illinois/epidemiology ; Humans ; Female ; Male ; Adult ; Bayes Theorem ; Middle Aged ; Census Tract ; Epidemics ; Illicit Drugs ; Socioeconomic Factors |
| Περίληψη: | Objectives. To examine geospatial polysubstance use overdose typologies and socio-structural determinants among overdose decedents in Cook County, Illinois, from 2017 to 2022. Methods. Decedents' addresses were geocoded and aggregated to census tract level (n = 1331). We conducted latent profile analysis to identify census tract profiles based on overdose fatality rates per 1000 census tract population across 9 drug types (alcohol, fentanyl, prescription opioids, heroin, cocaine, benzodiazepines, xylazine, methamphetamine/amphetamine, and other drugs). We used Bayesian spatial multinomial logistic regression to determine what census tract socio-structural determinants could predict polysubstance profile membership. Results. Three clusters of polysubstance use-low, moderate, and high-emerged with fentanyl, cocaine, and heroin dominating all clusters. In the adjusted model, census tracts with lower median household income were associated with increased odds of belonging to the moderate polysubstance use profile (odds ratio [OR] = 0.90; 95% Bayesian credible interval [CrI] = 0.85, 0.96) compared with the referent group. Also, census tracts with high Black isolation (quartile 4: OR = 2.93; 95% CrI = 1.44, 6.02) and higher population density (OR = 1.24; 95% CrI = 1.13, 1.37) were more likely to belong in the high polysubstance use profiles. Conclusions. Findings support the need for targeted resources tailored for particular neighborhoods. (Am J Public Health. 2026;116(8):1210-1219. https://doi.org/10.2105/AJPH.2026.308446). |
| Grant Information: | R01 DA059371 United States DA NIDA NIH HHS; T32 DA031099 United States DA NIDA NIH HHS; K01 DA062726 United States DA NIDA NIH HHS; K01 DA049900 United States DA NIDA NIH HHS; L60 DA061545 United States DA NIDA NIH HHS |
| Substance Nomenclature: | 0 (Illicit Drugs) |
| Entry Date(s): | Date Created: 20260618 Date Completed: 20260716 Latest Revision: 20260802 |
| Update Code: | 20260802 |
| PubMed Central ID: | PMC13374613 |
| DOI: | 10.2105/AJPH.2026.308446 |
| PMID: | 42314095 |
| Βάση Δεδομένων: | MEDLINE |
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