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Administration of antioxidants at parturition in Italian Mediterranean lactating buffaloes: findings in the postpartum.

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Τίτλος: Administration of antioxidants at parturition in Italian Mediterranean lactating buffaloes: findings in the postpartum.
Συγγραφείς: Frattina L; Department of Veterinary Medicine, University of Bari Aldo Moro, S.P. per Casamassima km. 3, 70010, Valenzano, BA, Italy., Carbonari A; Department of Veterinary Medicine, University of Bari Aldo Moro, S.P. per Casamassima km. 3, 70010, Valenzano, BA, Italy., Burgio M; Department of Veterinary Medicine, University of Bari Aldo Moro, S.P. per Casamassima km. 3, 70010, Valenzano, BA, Italy. matteo.burgio@uniba.it., Bramante G; Department of Veterinary Medicine, University of Bari Aldo Moro, S.P. per Casamassima km. 3, 70010, Valenzano, BA, Italy., Andriulo OM; Department of Veterinary Medicine, University of Bari Aldo Moro, S.P. per Casamassima km. 3, 70010, Valenzano, BA, Italy., Ceci E; Department of Veterinary Medicine, University of Bari Aldo Moro, S.P. per Casamassima km. 3, 70010, Valenzano, BA, Italy., Galdieri C; Department of Veterinary Medicine, University of Bari Aldo Moro, S.P. per Casamassima km. 3, 70010, Valenzano, BA, Italy., D'Onghia A; Associazione Regionale Allevatori Puglia, Strada Comunale San Nicola 2, 70017, Putignano, BA, Italy., Cicirelli V; Department of Veterinary Medicine, University of Bari Aldo Moro, S.P. per Casamassima km. 3, 70010, Valenzano, BA, Italy., Rizzo A; Department of Veterinary Medicine, University of Bari Aldo Moro, S.P. per Casamassima km. 3, 70010, Valenzano, BA, Italy.
Πηγή: Tropical animal health and production [Trop Anim Health Prod] 2026 Jun 12; Vol. 58 (5). Date of Electronic Publication: 2026 Jun 12.
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Springer Country of Publication: United States NLM ID: 1277355 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7438 (Electronic) Linking ISSN: 00494747 NLM ISO Abbreviation: Trop Anim Health Prod Subsets: MEDLINE
Imprint Name(s): Publication: 2005- : Heidelberg : Springer
Original Publication: Edinburgh, Livingstone.
Ιατρικοί όροι (MeSH): Buffaloes*/physiology , Lactation*/drug effects , Antioxidants*/administration & dosage , alpha-Tocopherol*/administration & dosage , Milk*/chemistry , beta Carotene*/administration & dosage, Injections, Intramuscular/veterinary ; Animals ; Female ; Pregnancy ; Parturition ; Postpartum Period ; Italy ; Vitamin A
Περίληψη: The transition period is an extremely critical phase for the Mediterranean lactating buffaloes, characterized by a state of oxidative stress. Oral administration of antioxidants is common. However, the aim of this study was to evaluate whether the intramuscular administration of a vitamin combination, containing α-tocopherol and β-carotene, could improve both milk quality and reproductive performance. The animals were divided into two groups: a group treated, at 24 h postpartum, with a vitamin combination (group D) and a control group (C). For milk quality, concentrations of retinol, α-tocopherol, fat, protein, lactose, Somatic Cell Count (SCC), non-fat dry matter (NFDM), casein, urea, pH, satured fatty acids (SFA), unsaturated fatty acids (UFA), monounsaturated fatty acids (MUFA) and poliunsaturated fatty acids (PUFA) in milk were assessed at 7 and 30 days post-treatment. Reproductive performance was evaluated using two parameters: pregnancy rate and the calving-conception interval. Retinol concentrations did not differ significantly between groups or across time points. α-tocopherol levels were significantly higher in group D compared to group C at T30 (0.35 ± 0.016 vs. 0.27 ± 0.015 mg/100 g; p < 0.05), whereas in group C exhibited a significant decrease over time. Fat, SFA, UFA, MUFA, and PUFA levels were significantly elevated in group D relative to group C (p < 0.05), while SCC showed a significant reduction in the treated group than the control one (104.4 ± 20.12 vs. 136.6 ± 32.24 × 10³ cells/mL; p < 0.05). No significant differences were observed in pregnancy rates; however, the calving-conception interval was significantly shortened in group D (62.23 ± 6.17 vs. 72.88 ± 5.49 days; p < 0.01). The obtained results indicate that the parenteral administration of the vitamin combination was associated with changes in selected milk quality parameters and with a shorter calving-conception interval.
(© 2026. The Author(s).)
Competing Interests: Declarations. Conflict of interest: None of the authors of this paper has a financial or personal relationship with other people or organizations that could inappropriately influence or bias the content of the paper.
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Contributed Indexing: Keywords: Buffaloes; Postpartum; Reproductive performance; α-tocopherol; β-carotene
Substance Nomenclature: 0 (Antioxidants)
H4N855PNZ1 (alpha-Tocopherol)
01YAE03M7J (beta Carotene)
11103-57-4 (Vitamin A)
Entry Date(s): Date Created: 20260612 Date Completed: 20260613 Latest Revision: 20260726
Update Code: 20260726
PubMed Central ID: PMC13263305
DOI: 10.1007/s11250-026-05137-z
PMID: 42283949
Βάση Δεδομένων: MEDLINE
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  Label: MeSH Terms
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  Data: &lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Buffaloes%22&quot;&gt;Buffaloes*&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Buffaloes+physiology%22&quot;&gt;physiology&lt;/searchLink&gt; &lt;br /&gt;&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Lactation%22&quot;&gt;Lactation*&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Lactation+drug+effects%22&quot;&gt;drug effects&lt;/searchLink&gt; &lt;br /&gt;&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Antioxidants%22&quot;&gt;Antioxidants*&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Antioxidants+administration+%26+dosage%22&quot;&gt;administration &amp; dosage&lt;/searchLink&gt; &lt;br /&gt;&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22alpha-Tocopherol%22&quot;&gt;alpha-Tocopherol*&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22alpha-Tocopherol+administration+%26+dosage%22&quot;&gt;administration &amp; dosage&lt;/searchLink&gt; &lt;br /&gt;&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Milk%22&quot;&gt;Milk*&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Milk+chemistry%22&quot;&gt;chemistry&lt;/searchLink&gt; &lt;br /&gt;&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22beta+Carotene%22&quot;&gt;beta Carotene*&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22beta+Carotene+administration+%26+dosage%22&quot;&gt;administration &amp; dosage&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Injections%2C+Intramuscular%22&quot;&gt;Injections, Intramuscular&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Injections%2C+Intramuscular+veterinary%22&quot;&gt;veterinary&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Animals%22&quot;&gt;Animals&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Female%22&quot;&gt;Female&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Pregnancy%22&quot;&gt;Pregnancy&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Parturition%22&quot;&gt;Parturition&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Postpartum+Period%22&quot;&gt;Postpartum Period&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Italy%22&quot;&gt;Italy&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Vitamin+A%22&quot;&gt;Vitamin A&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: The transition period is an extremely critical phase for the Mediterranean lactating buffaloes, characterized by a state of oxidative stress. Oral administration of antioxidants is common. However, the aim of this study was to evaluate whether the intramuscular administration of a vitamin combination, containing α-tocopherol and β-carotene, could improve both milk quality and reproductive performance. The animals were divided into two groups: a group treated, at 24&#160;h postpartum, with a vitamin combination (group D) and a control group (C). For milk quality, concentrations of retinol, α-tocopherol, fat, protein, lactose, Somatic Cell Count (SCC), non-fat dry matter (NFDM), casein, urea, pH, satured fatty acids (SFA), unsaturated fatty acids (UFA), monounsaturated fatty acids (MUFA) and poliunsaturated fatty acids (PUFA) in milk were assessed at 7 and 30 days post-treatment. Reproductive performance was evaluated using two parameters: pregnancy rate and the calving-conception interval. Retinol concentrations did not differ significantly between groups or across time points. α-tocopherol levels were significantly higher in group D compared to group C at T30 (0.35 &#177; 0.016 vs. 0.27 &#177; 0.015&#160;mg/100&#160;g; p &amp;lt; 0.05), whereas in group C exhibited a significant decrease over time. Fat, SFA, UFA, MUFA, and PUFA levels were significantly elevated in group D relative to group C (p &amp;lt; 0.05), while SCC showed a significant reduction in the treated group than the control one (104.4 &#177; 20.12 vs. 136.6 &#177; 32.24 &#215; 10&#179; cells/mL; p &amp;lt; 0.05). No significant differences were observed in pregnancy rates; however, the calving-conception interval was significantly shortened in group D (62.23 &#177; 6.17 vs. 72.88 &#177; 5.49 days; p &amp;lt; 0.01). The obtained results indicate that the parenteral administration of the vitamin combination was associated with changes in selected milk quality parameters and with a shorter calving-conception interval.&lt;br /&gt; (&#169; 2026. The Author(s).)
– Name: Abstract
  Label: Competing Interests
  Group: Ab
  Data: Declarations. Conflict of interest: None of the authors of this paper has a financial or personal relationship with other people or organizations that could inappropriately influence or bias the content of the paper.
– Name: Ref
  Label: References
  Group: RefInfo
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– Name: SubjectMinor
  Label: Contributed Indexing
  Group:
  Data: &lt;i&gt;Keywords: &lt;/i&gt;Buffaloes; Postpartum; Reproductive performance; α-tocopherol; β-carotene
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  Data: 0 (Antioxidants)&lt;br /&gt;H4N855PNZ1 (alpha-Tocopherol)&lt;br /&gt;01YAE03M7J (beta Carotene)&lt;br /&gt;11103-57-4 (Vitamin A)
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  Data: &lt;i&gt;Date Created: &lt;/i&gt;20260612 &lt;i&gt;Date Completed: &lt;/i&gt;20260613 &lt;i&gt;Latest Revision: &lt;/i&gt;20260726
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  Data: 10.1007/s11250-026-05137-z
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        Value: 10.1007/s11250-026-05137-z
    Languages:
      – Code: eng
        Text: English
    Subjects:
      – SubjectFull: Injections, Intramuscular veterinary
        Type: general
      – SubjectFull: Animals
        Type: general
      – SubjectFull: Female
        Type: general
      – SubjectFull: Pregnancy
        Type: general
      – SubjectFull: Parturition
        Type: general
      – SubjectFull: Postpartum Period
        Type: general
      – SubjectFull: Italy
        Type: general
      – SubjectFull: Vitamin A
        Type: general
      – SubjectFull: Buffaloes physiology
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      – SubjectFull: Lactation drug effects
        Type: general
      – SubjectFull: Antioxidants administration & dosage
        Type: general
      – SubjectFull: alpha-Tocopherol administration & dosage
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      – SubjectFull: Milk chemistry
        Type: general
      – SubjectFull: beta Carotene administration & dosage
        Type: general
    Titles:
      – TitleFull: Administration of antioxidants at parturition in Italian Mediterranean lactating buffaloes: findings in the postpartum.
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            – D: 12
              M: 06
              Text: 2026 Jun 12
              Type: published
              Y: 2026
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