Academic Journal

Artificial intelligence in forensic science: a systematic review. Part II: long-range postmortem interval estimation.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Artificial intelligence in forensic science: a systematic review. Part II: long-range postmortem interval estimation.
Συγγραφείς: Bugelli V; University of Parma, Parma, Italy., Calabrò F; University of Parma, Parma, Italy., Camatti J; University of Parma, Parma, Italy. jessika.camatti@unipr.it., Cecchi R; University of Modena and Reggio Emilia, Modena, Italy., Di Paolo M; University of Pisa, Pisa, Italy., Franceschetti L; University of Milano, Milan, Italy.
Πηγή: International journal of legal medicine [Int J Legal Med] 2026 Sep; Vol. 140 (5), pp. 3331-3343. Date of Electronic Publication: 2026 Jun 12.
Τύπος έκδοσης: Journal Article; Systematic Review; Review
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Springer International Country of Publication: Germany NLM ID: 9101456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1437-1596 (Electronic) Linking ISSN: 09379827 NLM ISO Abbreviation: Int J Legal Med Subsets: MEDLINE
Imprint Name(s): Original Publication: Heidelberg, FRG : Springer International, c1990-
Ιατρικοί όροι (MeSH): Forensic Sciences*/methods , Postmortem Changes* , Artificial Intelligence*, Humans ; Machine Learning ; Predictive Learning Models
Περίληψη: Postmortem interval (PMI) estimation remains a major challenge in forensic medicine due to the complex and multifactorial nature of decomposition processes. In recent years, artificial intelligence (AI) and machine learning techniques have been increasingly applied to improve PMI prediction. This systematic review aimed to evaluate the current evidence on AI-based models developed for PMI estimation. A systematic literature search was conducted in PubMed/MEDLINE and Scopus from database inception to 1 March 2026, following PRISMA 2020 guidelines. Studies were included if they applied AI, machine learning, or deep learning methods to estimate PMI using real postmortem datasets. Data extraction included study characteristics, data modality, AI model architecture, validation strategy, and reported performance metrics. A total of 64 studies met the inclusion criteria. The most common approach involved microbiome-based models (n = 29), followed by metabolomics and proteomics approaches (n = 11) and imaging-based AI models (n = 11). Random Forest algorithms were the most frequently used machine learning method, particularly in microbiome studies. Reported predictive performance varied widely across studies, with several models achieving high accuracy or low prediction errors depending on the data modality and PMI range investigated. AI represents a promising tool for improving the accuracy and objectivity of PMI estimation by enabling the integration of complex forensic datasets. However, current evidence is limited by heterogeneous methodologies, small datasets, and a lack of external validation. Future research should focus on large multicenter datasets, standardized validation protocols, and multimodal AI models integrating diverse forensic data sources.
(© 2026. The Author(s).)
Competing Interests: Declarations. Ethics approval and ethical standards: This study is a systematic review of published literature and did not involve new human participants or biological samples. Therefore, approval from an institutional review board or ethics committee was not required. Human ethics and consent to participate declaration: Not applicable. Clinical trial number: Not applicable. Competing interests: The authors declare no competing interests. One of the included studies is a previously published case report authored by members of the research team.
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Contributed Indexing: Keywords: Artificial intelligence; Decomposition; Forensic imaging; Forensic pathology; Machine learning; Postmortem interval
Entry Date(s): Date Created: 20260611 Date Completed: 20260822 Latest Revision: 20260903
Update Code: 20260903
PubMed Central ID: PMC13499855
DOI: 10.1007/s00414-026-03856-4
PMID: 42277392
Βάση Δεδομένων: MEDLINE
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  Label: Title
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  Data: Artificial intelligence in forensic science: a systematic review. Part II: long-range postmortem interval estimation.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Bugelli+V%22">Bugelli V</searchLink>; University of Parma, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Calabrò+F%22">Calabrò F</searchLink>; University of Parma, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Camatti+J%22">Camatti J</searchLink>; University of Parma, Parma, Italy. jessika.camatti@unipr.it.<br /><searchLink fieldCode="AU" term="%22Cecchi+R%22">Cecchi R</searchLink>; University of Modena and Reggio Emilia, Modena, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Paolo+M%22">Di Paolo M</searchLink>; University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Franceschetti+L%22">Franceschetti L</searchLink>; University of Milano, Milan, Italy.
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  Data: <searchLink fieldCode="JN" term="%229101456%22">International journal of legal medicine</searchLink> [Int J Legal Med] 2026 Sep; Vol. 140 (5), pp. 3331-3343. <i>Date of Electronic Publication: </i>2026 Jun 12.
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  Data: Journal Article; Systematic Review; Review
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+International%22">Springer International </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>9101456 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1437-1596 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209379827%22">09379827 </searchLink><i>NLM ISO Abbreviation: </i>Int J Legal Med <i>Subsets: </i>MEDLINE
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  Data: <i>Original Publication</i>: Heidelberg, FRG : Springer International, c1990-
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  Data: <searchLink fieldCode="MM" term="%22Forensic+Sciences%22">Forensic Sciences*</searchLink>/<searchLink fieldCode="MM" term="%22Forensic+Sciences+methods%22">methods</searchLink> <br /><searchLink fieldCode="MM" term="%22Postmortem+Changes%22">Postmortem Changes*</searchLink> <br /><searchLink fieldCode="MM" term="%22Artificial+Intelligence%22">Artificial Intelligence*</searchLink><br /><searchLink fieldCode="MH" term="%22Humans%22">Humans</searchLink> ; <searchLink fieldCode="MH" term="%22Machine+Learning%22">Machine Learning</searchLink> ; <searchLink fieldCode="MH" term="%22Predictive+Learning+Models%22">Predictive Learning Models</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Postmortem interval (PMI) estimation remains a major challenge in forensic medicine due to the complex and multifactorial nature of decomposition processes. In recent years, artificial intelligence (AI) and machine learning techniques have been increasingly applied to improve PMI prediction. This systematic review aimed to evaluate the current evidence on AI-based models developed for PMI estimation. A systematic literature search was conducted in PubMed/MEDLINE and Scopus from database inception to 1 March 2026, following PRISMA 2020 guidelines. Studies were included if they applied AI, machine learning, or deep learning methods to estimate PMI using real postmortem datasets. Data extraction included study characteristics, data modality, AI model architecture, validation strategy, and reported performance metrics. A total of 64 studies met the inclusion criteria. The most common approach involved microbiome-based models (n = 29), followed by metabolomics and proteomics approaches (n = 11) and imaging-based AI models (n = 11). Random Forest algorithms were the most frequently used machine learning method, particularly in microbiome studies. Reported predictive performance varied widely across studies, with several models achieving high accuracy or low prediction errors depending on the data modality and PMI range investigated. AI represents a promising tool for improving the accuracy and objectivity of PMI estimation by enabling the integration of complex forensic datasets. However, current evidence is limited by heterogeneous methodologies, small datasets, and a lack of external validation. Future research should focus on large multicenter datasets, standardized validation protocols, and multimodal AI models integrating diverse forensic data sources.<br /> (© 2026. The Author(s).)
– Name: Abstract
  Label: Competing Interests
  Group: Ab
  Data: Declarations. Ethics approval and ethical standards: This study is a systematic review of published literature and did not involve new human participants or biological samples. Therefore, approval from an institutional review board or ethics committee was not required. Human ethics and consent to participate declaration: Not applicable. Clinical trial number: Not applicable. Competing interests: The authors declare no competing interests. One of the included studies is a previously published case report authored by members of the research team.
– Name: Ref
  Label: References
  Group: RefInfo
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  Data: <i>Keywords: </i>Artificial intelligence; Decomposition; Forensic imaging; Forensic pathology; Machine learning; Postmortem interval
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  Data: <i>Date Created: </i>20260611 <i>Date Completed: </i>20260822 <i>Latest Revision: </i>20260903
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        Value: 10.1007/s00414-026-03856-4
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        Text: English
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      – SubjectFull: Humans
        Type: general
      – SubjectFull: Machine Learning
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      – SubjectFull: Predictive Learning Models
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      – SubjectFull: Forensic Sciences methods
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      – SubjectFull: Postmortem Changes
        Type: general
      – SubjectFull: Artificial Intelligence
        Type: general
    Titles:
      – TitleFull: Artificial intelligence in forensic science: a systematic review. Part II: long-range postmortem interval estimation.
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              Text: 2026 Sep
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              Y: 2026
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