Academic Journal
Locally Linearized Approximation of RF Pulse Propagators for Faster Simulation of Magnetization Dynamics With Slice Profile Effects in 2D MR Fingerprinting.
| Title: | Locally Linearized Approximation of RF Pulse Propagators for Faster Simulation of Magnetization Dynamics With Slice Profile Effects in 2D MR Fingerprinting. |
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| Authors: | Mickevicius NJ; Department of Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. |
| Source: | Magnetic resonance in medicine [Magn Reson Med] 2026 Oct; Vol. 96 (4), pp. 1909-1915. Date of Electronic Publication: 2026 Jun 08. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 8505245 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-2594 (Electronic) Linking ISSN: 07403194 NLM ISO Abbreviation: Magn Reson Med Subsets: MEDLINE |
| Imprint Name(s): | Publication: 1999- : New York, NY : Wiley Original Publication: San Diego : Academic Press |
| MeSH Terms: | Magnetic Resonance Imaging*/methods , Image Processing, Computer-Assisted*/methods , Image Interpretation, Computer-Assisted*/methods , Signal Processing, Computer-Assisted*, Phantoms, Imaging ; Algorithms ; Computer Simulation ; Radio Waves ; Humans ; Reproducibility of Results ; Linear Models ; Sensitivity and Specificity |
| Abstract: | Purpose: The objective for this study is to decrease the computation time of magnetic resonance fingerprinting dictionary computations that include slice profile effects. Theory and Methods: A locally linearized approximation to RF pulse propagators across RF scaling factors was derived and used to decrease the computational burden of MRF dictionary computation. MR fingerprinting phantom experiments were carried out at 3T to assess the practical feasibility of using dictionaries approximated with the proposed approach. Results: Using linearizations at 10 INLINEMATH scaling factors produced root mean square differences in estimated INLINEMATH and INLINEMATH of 1.17% and 1.98%, respectively, between dictionaries generated using a full Bloch simulation and the locally linear approximation while decreasing computation time by a factor of 10. Conclusion: The proposed locally linear approximation significantly accelerates slice-profile-aware MRF simulations while maintaining high accuracy, enabling practical incorporation of realistic RF pulse effects into large-scale dictionary computations. (© 2026 International Society for Magnetic Resonance in Medicine.) |
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| Contributed Indexing: | Keywords: MR fingerprinting; RF pulse simulation; quantitative MRI |
| Entry Date(s): | Date Created: 20260608 Date Completed: 20260729 Latest Revision: 20260731 |
| Update Code: | 20260731 |
| PubMed Central ID: | PMC13419243 |
| DOI: | 10.1002/mrm.70462 |
| PMID: | 42260330 |
| Database: | MEDLINE |
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