Optimising screening efficiency in evidence synthesis on health Technology: A simulation study using ASReview.

Bibliographic Details
Title: Optimising screening efficiency in evidence synthesis on health Technology: A simulation study using ASReview.
Authors: Dias de Oliveira JM; Bridge Laboratory, Federal University of Santa Catarina, Florianópolis, Brazil; Graduate Program in Dentistry, Federal University of Santa Catarina, Florianópolis, Brazil. Electronic address: julia.meller@bridge.ufsc.br., Mello AT; Bridge Laboratory, Federal University of Santa Catarina, Florianópolis, Brazil; Postgraduate Program in Nutrition, Federal University of Santa Catarina (UFSC), Florianópolis, Brazil. Electronic address: arthur.mello@bridge.ufsc.br., Scandolara DH; Bridge Laboratory, Federal University of Santa Catarina, Florianópolis, Brazil; Postgraduate Program in Engineering, Management and Knowledge Media, Florianópolis, Brazil. Electronic address: daniel.scandolara@bridge.ufsc.br., Celuppi IC; Bridge Laboratory, Federal University of Santa Catarina, Florianópolis, Brazil. Electronic address: ianka@bridge.ufsc.br., Corrêa Rampinelli VP; Bridge Laboratory, Federal University of Santa Catarina, Florianópolis, Brazil; Department of Public Health, Federal University of Santa Catarina, Araranguá, Brazil. Electronic address: vanessa.correa@bridge.ufsc.br., Wazlawick RS; Bridge Laboratory, Federal University of Santa Catarina, Florianópolis, Brazil; Department of Informatics and Statistics, Federal University of Santa Catarina, Florianópolis, Brazil. Electronic address: raul@bridge.ufsc.br., Dalmarco EM; Bridge Laboratory, Federal University of Santa Catarina, Florianópolis, Brazil; Department of Clinical Analysis, Federal University of Santa Catarina, Florianópolis, Brazil. Electronic address: dalmarco@bridge.ufsc.br.
Source: International journal of medical informatics [Int J Med Inform] 2026 Sep 15; Vol. 218, pp. 106516. Date of Electronic Publication: 2026 Jun 03.
Publication Type: Journal Article; Evidence Synthesis
Language: English
Journal Info: Publisher: Elsevier Science Ireland Ltd Country of Publication: Ireland NLM ID: 9711057 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8243 (Electronic) Linking ISSN: 13865056 NLM ISO Abbreviation: Int J Med Inform Subsets: MEDLINE
Imprint Name(s): Original Publication: Shannon, Co. Clare, Ireland : Elsevier Science Ireland Ltd., c1997-
MeSH Terms: Computer Simulation* , Biomedical Technology*, Humans ; Retrospective Studies ; Support Vector Machine
Abstract: Objective: This study evaluated model-configuration and stopping-rule decisions when using active learning-based title-and-abstract screening in health technology evidence syntheses.
Methods: We conducted retrospective simulations using seven pre-labelled datasets from systematic, scoping, and overview reviews in health technology. Simulations were implemented with ASReview Makita and compared lightweight configurations based on one-hot encoding or term frequency-inverse document frequency with naive Bayes, logistic regression, random forest, and support vector machine classifiers. Performance was evaluated using normalised recall regret ("loss"), work saved over sampling at 95% (WSS@95) and 100% recall (WSS@100), early recall, and K%-consecutive-irrelevant stopping rules. Repeated simulations and exploratory dataset-level analyses were conducted for the highest-ranked configuration.
Results: SVM + TF-IDF (with bigrams) had the most favourable overall performance, with an average loss of 0.08 (95% CI 0.06 to 0.09), WSS@95 of 0.70 (95% CI 0.59 to 0.79), and WSS@100 of 0.50 (95% CI 0.30 to 0.69). At a fixed 7% consecutive-irrelevant stopping rule, all datasets reached at least 95% recall in the main analysis, with mean recall of 98%. In repeated simulations, the fixed 7% rule achieved mean recall of 97%; however, one very low-prevalence dataset did not reach 95% recall until K = 33%. Exploratory analyses suggested that relevant-record prevalence, textual similarity among relevant records, and abstract completeness may help explain variation in model performance and stopping-rule reliability, although these analyses were hypothesis-generating.
Conclusion: Active learning-based screening reduced workload in these health technology datasets, but its use requires explicit implementation choices. SVM + TF-IDF (with bigrams) was the most pragmatic initial configuration, and a 7% consecutive-irrelevant rule was a useful stopping heuristic. However, stopping decisions should depend on the review's tolerance for missed studies, dataset quality, topic heterogeneity, and available safeguards, rather than on a fixed threshold alone.
(Copyright © 2026 The Authors. Published by Elsevier B.V. All rights reserved.)
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Contributed Indexing: Keywords: ASReview; Computational simulation; Evidence-based health science; Systematic review
Entry Date(s): Date Created: 20260603 Date Completed: 20260628 Latest Revision: 20260628
Update Code: 20260628
DOI: 10.1016/j.ijmedinf.2026.106516
PMID: 42235438
Database: MEDLINE
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