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Foraging crumbles reduce severe aggression in laboratory mice.

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Τίτλος: Foraging crumbles reduce severe aggression in laboratory mice.
Συγγραφείς: Bennett MB; George Mason University, Fairfax, VA, United States; University of Texas at San Antonio Health Science Center, San Antonio, TX, United States. Electronic address: bennettm1@livemail.uthscsa.edu., Booth AB; George Mason University, Fairfax, VA, United States., Murdoch EQ; George Mason University, Fairfax, VA, United States., Flinn JM; George Mason University, Fairfax, VA, United States.
Πηγή: Physiology & behavior [Physiol Behav] 2026 Oct 15; Vol. 315, pp. 115401. Date of Electronic Publication: 2026 May 29.
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0151504 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-507X (Electronic) Linking ISSN: 00319384 NLM ISO Abbreviation: Physiol Behav Subsets: MEDLINE
Imprint Name(s): Publication: New York NY : Elsevier Science
Original Publication: Oxford, Eng., Long Island City, Pergamon Press.
Ιατρικοί όροι (MeSH): Aggression*/physiology , Aggression*/psychology , Housing, Animal*, Circadian Rhythm/physiology ; Anxiety/psychology ; Animals ; Male ; Mice
Περίληψη: Providing foraging crumbles in mouse cages is one method used in efforts to reduce aggression in laboratory mice. However, no studies have yet examined the effects of this procedure. Therefore, we investigated whether foraging crumbles decrease aggression, increase aggression, or do not affect the aggression observed in male laboratory mice. Results indicated that foraging crumbles were associated with a decrease in severe aggression, particularly that which caused injury. At the 100-day mark, to ensure the crumbles would not affect experimentation and to elucidate the behavioral effect of isolation on mice, four behavioral assays were run. Crumbles did not significantly interfere with the mice's cognitive, anxiety, or circadian rhythm performances.
(Copyright © 2026. Published by Elsevier Inc.)
Contributed Indexing: Keywords: Aggression; Enrichment; Housing; Mouse
Entry Date(s): Date Created: 20260530 Date Completed: 20260807 Latest Revision: 20260807
Update Code: 20260808
DOI: 10.1016/j.physbeh.2026.115401
PMID: 42217534
Βάση Δεδομένων: MEDLINE
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  Data: Foraging crumbles reduce severe aggression in laboratory mice.
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  Data: <searchLink fieldCode="AU" term="%22Bennett+MB%22">Bennett MB</searchLink>; George Mason University, Fairfax, VA, United States; University of Texas at San Antonio Health Science Center, San Antonio, TX, United States. Electronic address: bennettm1@livemail.uthscsa.edu.<br /><searchLink fieldCode="AU" term="%22Booth+AB%22">Booth AB</searchLink>; George Mason University, Fairfax, VA, United States.<br /><searchLink fieldCode="AU" term="%22Murdoch+EQ%22">Murdoch EQ</searchLink>; George Mason University, Fairfax, VA, United States.<br /><searchLink fieldCode="AU" term="%22Flinn+JM%22">Flinn JM</searchLink>; George Mason University, Fairfax, VA, United States.
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  Data: <searchLink fieldCode="MM" term="%22Aggression%22">Aggression*</searchLink>/<searchLink fieldCode="MM" term="%22Aggression+physiology%22">physiology</searchLink> <br /><searchLink fieldCode="MM" term="%22Aggression%22">Aggression*</searchLink>/<searchLink fieldCode="MM" term="%22Aggression+psychology%22">psychology</searchLink> <br /><searchLink fieldCode="MM" term="%22Housing%2C+Animal%22">Housing, Animal*</searchLink><br /><searchLink fieldCode="MH" term="%22Circadian+Rhythm%22">Circadian Rhythm</searchLink>/<searchLink fieldCode="MH" term="%22Circadian+Rhythm+physiology%22">physiology</searchLink> ; <searchLink fieldCode="MH" term="%22Anxiety%22">Anxiety</searchLink>/<searchLink fieldCode="MH" term="%22Anxiety+psychology%22">psychology</searchLink> ; <searchLink fieldCode="MH" term="%22Animals%22">Animals</searchLink> ; <searchLink fieldCode="MH" term="%22Male%22">Male</searchLink> ; <searchLink fieldCode="MH" term="%22Mice%22">Mice</searchLink>
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  Data: Providing foraging crumbles in mouse cages is one method used in efforts to reduce aggression in laboratory mice. However, no studies have yet examined the effects of this procedure. Therefore, we investigated whether foraging crumbles decrease aggression, increase aggression, or do not affect the aggression observed in male laboratory mice. Results indicated that foraging crumbles were associated with a decrease in severe aggression, particularly that which caused injury. At the 100-day mark, to ensure the crumbles would not affect experimentation and to elucidate the behavioral effect of isolation on mice, four behavioral assays were run. Crumbles did not significantly interfere with the mice's cognitive, anxiety, or circadian rhythm performances.<br /> (Copyright © 2026. Published by Elsevier Inc.)
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