Academic Journal
Challenges to human papillomavirus vaccination among young girls in Morocco: A national cross-sectional study.
| Τίτλος: | Challenges to human papillomavirus vaccination among young girls in Morocco: A national cross-sectional study. |
|---|---|
| Συγγραφείς: | Essayagh T; Hassan First University of Settat, Institut Supérieur des Sciences de la Santé, Laboratoire des Sciences et Ingénierie Biomédicales, Biophysique et Santé, Settat, Morocco., Essayagh M; Office National de Sécurité Sanitaire des produits Alimentaires, Meknès, Morocco., Slibani H; Hassan First University of Settat, Institut Supérieur des Sciences de la Santé, Laboratoire des Sciences et Ingénierie Biomédicales, Biophysique et Santé, Settat, Morocco., El Hachimi S; Hassan First University of Settat, Institut Supérieur des Sciences de la Santé, Laboratoire des Sciences et Ingénierie Biomédicales, Biophysique et Santé, Settat, Morocco., Nmila K; Hassan First University of Settat, Institut Supérieur des Sciences de la Santé, Laboratoire des Sciences et Ingénierie Biomédicales, Biophysique et Santé, Settat, Morocco., Addakiri K; Hassan First University of Settat, Institut Supérieur des Sciences de la Santé, Laboratoire des Sciences et Ingénierie Biomédicales, Biophysique et Santé, Settat, Morocco., Zadran R; National Infectious Diseases Hospital Laboratory, Kabul, Afghanistan., Essayagh S; Hassan First University of Settat, Faculté des Sciences et Techniques, Laboratoire Agroalimentaire et Santé, Settat, Morocco. |
| Πηγή: | PloS one [PLoS One] 2026 May 20; Vol. 21 (5), pp. e0347783. Date of Electronic Publication: 2026 May 20 (Print Publication: 2026). |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: San Francisco, CA : Public Library of Science |
| Ιατρικοί όροι (MeSH): | Papillomavirus Vaccines*/administration & dosage , Human Papillomavirus Viruses*/immunology , Vaccination*/psychology , Vaccination*/statistics & numerical data , Papillomavirus Infections*/prevention & control , Vaccination Hesitancy*/statistics & numerical data , Vaccination Hesitancy*/psychology, Morocco/epidemiology ; Uterine Cervical Neoplasms/prevention & control ; Uterine Cervical Neoplasms/virology ; Humans ; Female ; Cross-Sectional Studies ; Adolescent ; Health Knowledge, Attitudes, Practice ; Child ; Risk Factors ; Unvaccinated Persons |
| Περίληψη: | Background: The human papillomavirus (HPV) vaccine helps significantly reduce the incidence of cervical cancer. However, in many countries, its adoption remains limited. In this context, our study aimed to measure the prevalence of HPV vaccination hesitancy among young girls and to identify its associated risk factors. Methods: From 10th April to 30th June 2025, a cross-sectional survey was conducted in Morocco among girls aged 11-14 attending middle school. Face-to-face interviews gathered sociodemographic data, HPV knowledge, and vaccination attitudes. Multivariate logistic regression identified risk variables for vaccine hesitancy. Results: A total of 1,836 participants were collected with a mean age of 13.0 ± 0.8 years. The percentage of vaccine hesitancy reached 88.8%. The main risk factors were unvaccinated pairs (AOR = 11.78; CI [7.67-18.0]), paternal illiteracy (AOR = 7.67; [1.99-29.55]), low recommendation of the vaccine by health personnel (AOR = 4.14; [2.44-7.02]), belief that the vaccine promotes sexual activity (AOR = 3.10; [2.01-4.79]), insufficient knowledge of the target population (AOR = 2.51; [1.63-3.85]), perception of adverse effects (AOR = 1.97; [1.31-2.98]), insufficient knowledge of the number of doses required (AOR = 1.76; [1.06-2.92]), fear of vaccination (AOR = 1.71; [1.14-2.58]), fear of regretting vaccination (AOR = 1.55; [1.02-2.36]), and age (AOR = 1.34; [1.06-1.69]). Conclusion: HPV vaccination hesitancy remains high and is shaped by social, educational, and cultural factors. These findings underscore the need for targeted educational initiatives and increased awareness among healthcare professionals. Integrating vaccination into school health programs may help improve uptake. (Copyright: © 2026 Essayagh et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.) |
| Competing Interests: | The authors have declared that no competing interests exist. |
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| Substance Nomenclature: | 0 (Papillomavirus Vaccines) |
| Entry Date(s): | Date Created: 20260520 Date Completed: 20260717 Latest Revision: 20260813 |
| Update Code: | 20260813 |
| PubMed Central ID: | PMC13189319 |
| DOI: | 10.1371/journal.pone.0347783 |
| PMID: | 42160355 |
| Βάση Δεδομένων: | MEDLINE |
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