Academic Journal
Improve genetic quality control to increase rigor and reproducibility of mouse research.
| Τίτλος: | Improve genetic quality control to increase rigor and reproducibility of mouse research. |
|---|---|
| Συγγραφείς: | Pardo-Manuel de Villena F; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA.; MMRRC-UNC, UNC-CH, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, School of Medicine, UNC-CH, Chapel Hill, NC, USA., Amos-Landgraf JM; MMRRC-MU, Department of Pathobiology and Integrative Biosciences, University of Missouri, Columbia, MO, USA., Bell TA; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA., Blanchard MW; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA.; MMRRC-UNC, UNC-CH, Chapel Hill, NC, USA., Brennan J; MMRRC-UNC, UNC-CH, Chapel Hill, NC, USA., Carlson C; MMRRC-ICSC (Informatics, Coordination and Service Center), Genome Center, University of California-Davis (UC-D), Davis, CA, USA., Ciavatta DJ; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA.; MMRRC-UNC, UNC-CH, Chapel Hill, NC, USA.; UNC Kidney Center, School of Medicine, UNC-CH, Chapel Hill, NC, USA., Cotney PA; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA., Ferris MT; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA., Hock P; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA.; MMRRC-UNC, UNC-CH, Chapel Hill, NC, USA., Korf I; MMRRC-ICSC (Informatics, Coordination and Service Center), Genome Center, University of California-Davis (UC-D), Davis, CA, USA.; Department of Molecular and Cellular Biology, College of Biological Sciences, UC-D, Davis, CA, USA., Lloyd KCK; Department of Molecular and Cellular Biology, College of Biological Sciences, UC-D, Davis, CA, USA.; Department of Surgery, School of Medicine, UC-D, Sacramento, CA, USA.; MMRRC-UC Davis and Mouse Biology Program, UC-D, Davis, CA, USA., Lutz C; The Jackson Laboratory, Bar Harbor, ME, USA., Lynch RM; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA.; MMRRC-UNC, UNC-CH, Chapel Hill, NC, USA., Magnuson T; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA.; MMRRC-UNC, UNC-CH, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, School of Medicine, UNC-CH, Chapel Hill, NC, USA., Murray SA; The Jackson Laboratory, Bar Harbor, ME, USA., Patel S; MMRRC-ICSC (Informatics, Coordination and Service Center), Genome Center, University of California-Davis (UC-D), Davis, CA, USA., Reinholdt LG; The Jackson Laboratory, Bar Harbor, ME, USA., Sigmon JS; MMRRC-UNC, UNC-CH, Chapel Hill, NC, USA.; Department of Computer Science, UNC-CH, Chapel Hill, NC, USA., Willis B; MMRRC-UC Davis and Mouse Biology Program, UC-D, Davis, CA, USA., Xenakis JG; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA. |
| Πηγή: | Science (New York, N.Y.) [Science] 2026 May 14; Vol. 392 (6799), pp. 698-700. Date of Electronic Publication: 2026 May 14. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Imprint Name(s): | Publication: Original Publication: New York, N.Y. : [s.n.] 1880- |
| Ιατρικοί όροι (MeSH): | Animal Experimentation*/standards , Mice, Mutant Strains*/genetics , Quality Control*, Animals ; Mice ; Reproducibility of Results |
| Περίληψη: | A quality control process using the latest technology can help address inconsistencies and expectations. |
| References: | Nat Genet. 2011 May 29;43(7):648-55. (PMID: 21623374) Elife. 2022 Feb 04;11:. (PMID: 35119362) PeerJ. 2013 Sep 05;1:e148. (PMID: 24032093) Genetics. 2020 Dec;216(4):905-930. (PMID: 33067325) Science. 2013 Dec 20;342(6165):1508-12. (PMID: 24357318) J Clin Invest. 2023 Sep 15;133(18):. (PMID: 37712424) Am J Hum Genet. 2017 Aug 3;101(2):177-191. (PMID: 28777930) Mamm Genome. 2024 Dec;35(4):524-536. (PMID: 39304538) Nat Commun. 2024 Jul 2;15(1):5574. (PMID: 38956430) Science. 1995 Jul 14;269(5221):230-4. (PMID: 7618084) Science. 2026 May 14;392(6799):698-700. (PMID: 42133765) |
| Grant Information: | P30 CA093373 United States CA NCI NIH HHS; U42 OD010983 United States OD NIH HHS; U42 OD010924 United States OD NIH HHS; U42 OD012210 United States OD NIH HHS; U42 OD010921 United States OD NIH HHS; U42 OD010918 United States OD NIH HHS; P42 ES031007 United States ES NIEHS NIH HHS |
| Entry Date(s): | Date Created: 20260514 Date Completed: 20260514 Latest Revision: 20261009 |
| Update Code: | 20261009 |
| PubMed Central ID: | PMC13215183 |
| DOI: | 10.1126/science.aec3177 |
| PMID: | 42133765 |
| Βάση Δεδομένων: | MEDLINE |
| FullText | Text: Availability: 0 |
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| Header | DbId: cmedm DbLabel: MEDLINE An: 42133765 AccessLevel: 3 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Improve genetic quality control to increase rigor and reproducibility of mouse research. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Pardo-Manuel+de+Villena+F%22">Pardo-Manuel de Villena F</searchLink>; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA.; MMRRC-UNC, UNC-CH, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, School of Medicine, UNC-CH, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Amos-Landgraf+JM%22">Amos-Landgraf JM</searchLink>; MMRRC-MU, Department of Pathobiology and Integrative Biosciences, University of Missouri, Columbia, MO, USA.<br /><searchLink fieldCode="AU" term="%22Bell+TA%22">Bell TA</searchLink>; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Blanchard+MW%22">Blanchard MW</searchLink>; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA.; MMRRC-UNC, UNC-CH, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Brennan+J%22">Brennan J</searchLink>; MMRRC-UNC, UNC-CH, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Carlson+C%22">Carlson C</searchLink>; MMRRC-ICSC (Informatics, Coordination and Service Center), Genome Center, University of California-Davis (UC-D), Davis, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ciavatta+DJ%22">Ciavatta DJ</searchLink>; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA.; MMRRC-UNC, UNC-CH, Chapel Hill, NC, USA.; UNC Kidney Center, School of Medicine, UNC-CH, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Cotney+PA%22">Cotney PA</searchLink>; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Ferris+MT%22">Ferris MT</searchLink>; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Hock+P%22">Hock P</searchLink>; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA.; MMRRC-UNC, UNC-CH, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Korf+I%22">Korf I</searchLink>; MMRRC-ICSC (Informatics, Coordination and Service Center), Genome Center, University of California-Davis (UC-D), Davis, CA, USA.; Department of Molecular and Cellular Biology, College of Biological Sciences, UC-D, Davis, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lloyd+KCK%22">Lloyd KCK</searchLink>; Department of Molecular and Cellular Biology, College of Biological Sciences, UC-D, Davis, CA, USA.; Department of Surgery, School of Medicine, UC-D, Sacramento, CA, USA.; MMRRC-UC Davis and Mouse Biology Program, UC-D, Davis, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lutz+C%22">Lutz C</searchLink>; The Jackson Laboratory, Bar Harbor, ME, USA.<br /><searchLink fieldCode="AU" term="%22Lynch+RM%22">Lynch RM</searchLink>; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA.; MMRRC-UNC, UNC-CH, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Magnuson+T%22">Magnuson T</searchLink>; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA.; MMRRC-UNC, UNC-CH, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, School of Medicine, UNC-CH, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Murray+SA%22">Murray SA</searchLink>; The Jackson Laboratory, Bar Harbor, ME, USA.<br /><searchLink fieldCode="AU" term="%22Patel+S%22">Patel S</searchLink>; MMRRC-ICSC (Informatics, Coordination and Service Center), Genome Center, University of California-Davis (UC-D), Davis, CA, USA.<br /><searchLink fieldCode="AU" term="%22Reinholdt+LG%22">Reinholdt LG</searchLink>; The Jackson Laboratory, Bar Harbor, ME, USA.<br /><searchLink fieldCode="AU" term="%22Sigmon+JS%22">Sigmon JS</searchLink>; MMRRC-UNC, UNC-CH, Chapel Hill, NC, USA.; Department of Computer Science, UNC-CH, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Willis+B%22">Willis B</searchLink>; MMRRC-UC Davis and Mouse Biology Program, UC-D, Davis, CA, USA.<br /><searchLink fieldCode="AU" term="%22Xenakis+JG%22">Xenakis JG</searchLink>; Department of Genetics, University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220404511%22">Science (New York, N.Y.)</searchLink> [Science] 2026 May 14; Vol. 392 (6799), pp. 698-700. <i>Date of Electronic Publication: </i>2026 May 14. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: Language Label: Language Group: Lang Data: English – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0404511 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1095-9203 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200368075%22">00368075 </searchLink><i>NLM ISO Abbreviation: </i>Science <i>Subsets: </i>MEDLINE – Name: PublisherInfo Label: Imprint Name(s) Group: PubInfo Data: <i>Publication</i>: <Oct. 4, 1991- > : Washington, DC : American Association for the Advancement of Science<br /><i>Original Publication</i>: New York, N.Y. : [s.n.] 1880- – Name: SubjectMESH Label: MeSH Terms Group: Su Data: <searchLink fieldCode="MM" term="%22Animal+Experimentation%22">Animal Experimentation*</searchLink>/<searchLink fieldCode="MM" term="%22Animal+Experimentation+standards%22">standards</searchLink> <br /><searchLink fieldCode="MM" term="%22Mice%2C+Mutant+Strains%22">Mice, Mutant Strains*</searchLink>/<searchLink fieldCode="MM" term="%22Mice%2C+Mutant+Strains+genetics%22">genetics</searchLink> <br /><searchLink fieldCode="MM" term="%22Quality+Control%22">Quality Control*</searchLink><br /><searchLink fieldCode="MH" term="%22Animals%22">Animals</searchLink> ; <searchLink fieldCode="MH" term="%22Mice%22">Mice</searchLink> ; <searchLink fieldCode="MH" term="%22Reproducibility+of+Results%22">Reproducibility of Results</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: A quality control process using the latest technology can help address inconsistencies and expectations. – Name: Ref Label: References Group: RefInfo Data: Nat Genet. 2011 May 29;43(7):648-55. (PMID: <searchLink fieldCode="PM" term="%2221623374%22">21623374)</searchLink><br />Elife. 2022 Feb 04;11:. (PMID: <searchLink fieldCode="PM" term="%2235119362%22">35119362)</searchLink><br />PeerJ. 2013 Sep 05;1:e148. (PMID: <searchLink fieldCode="PM" term="%2224032093%22">24032093)</searchLink><br />Genetics. 2020 Dec;216(4):905-930. (PMID: <searchLink fieldCode="PM" term="%2233067325%22">33067325)</searchLink><br />Science. 2013 Dec 20;342(6165):1508-12. (PMID: <searchLink fieldCode="PM" term="%2224357318%22">24357318)</searchLink><br />J Clin Invest. 2023 Sep 15;133(18):. (PMID: <searchLink fieldCode="PM" term="%2237712424%22">37712424)</searchLink><br />Am J Hum Genet. 2017 Aug 3;101(2):177-191. (PMID: <searchLink fieldCode="PM" term="%2228777930%22">28777930)</searchLink><br />Mamm Genome. 2024 Dec;35(4):524-536. (PMID: <searchLink fieldCode="PM" term="%2239304538%22">39304538)</searchLink><br />Nat Commun. 2024 Jul 2;15(1):5574. (PMID: <searchLink fieldCode="PM" term="%2238956430%22">38956430)</searchLink><br />Science. 1995 Jul 14;269(5221):230-4. (PMID: <searchLink fieldCode="PM" term="%227618084%22">7618084)</searchLink><br />Science. 2026 May 14;392(6799):698-700. (PMID: <searchLink fieldCode="PM" term="%2242133765%22">42133765)</searchLink> – Name: GrantInfo Label: Grant Information Group: Grant Data: P30 CA093373 United States CA NCI NIH HHS; U42 OD010983 United States OD NIH HHS; U42 OD010924 United States OD NIH HHS; U42 OD012210 United States OD NIH HHS; U42 OD010921 United States OD NIH HHS; U42 OD010918 United States OD NIH HHS; P42 ES031007 United States ES NIEHS NIH HHS – Name: DateEntry Label: Entry Date(s) Group: Date Data: <i>Date Created: </i>20260514 <i>Date Completed: </i>20260514 <i>Latest Revision: </i>20261009 – Name: DateUpdate Label: Update Code Group: Date Data: 20261009 – Name: PubmedCentralID Label: PubMed Central ID Group: ID Data: PMC13215183 – Name: DOI Label: DOI Group: ID Data: 10.1126/science.aec3177 – Name: AN Label: PMID Group: ID Data: 42133765 |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=cmedm&AN=42133765 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1126/science.aec3177 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 698 Subjects: – SubjectFull: Animals Type: general – SubjectFull: Mice Type: general – SubjectFull: Reproducibility of Results Type: general – SubjectFull: Animal Experimentation standards Type: general – SubjectFull: Mice, Mutant Strains genetics Type: general – SubjectFull: Quality Control Type: general Titles: – TitleFull: Improve genetic quality control to increase rigor and reproducibility of mouse research. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Pardo-Manuel de Villena F – PersonEntity: Name: NameFull: Amos-Landgraf JM – PersonEntity: Name: NameFull: Bell TA – PersonEntity: Name: NameFull: Blanchard MW – PersonEntity: Name: NameFull: Brennan J – PersonEntity: Name: NameFull: Carlson C – PersonEntity: Name: NameFull: Ciavatta DJ – PersonEntity: Name: NameFull: Cotney PA – PersonEntity: Name: NameFull: Ferris MT – PersonEntity: Name: NameFull: Hock P – PersonEntity: Name: NameFull: Korf I – PersonEntity: Name: NameFull: Lloyd KCK – PersonEntity: Name: NameFull: Lutz C – PersonEntity: Name: NameFull: Lynch RM – PersonEntity: Name: NameFull: Magnuson T – PersonEntity: Name: NameFull: Murray SA – PersonEntity: Name: NameFull: Patel S – PersonEntity: Name: NameFull: Reinholdt LG – PersonEntity: Name: NameFull: Sigmon JS – PersonEntity: Name: NameFull: Willis B – PersonEntity: Name: NameFull: Xenakis JG IsPartOfRelationships: – BibEntity: Dates: – D: 14 M: 05 Text: 2026 May 14 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1095-9203 Numbering: – Type: volume Value: 392 – Type: issue Value: 6799 Titles: – TitleFull: Science (New York, N.Y.) Type: main |
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