Academic Journal
Προβολή σε EDS
Συνδεδεμένο Πλήρες Κείμενο

The link between basic visual processing and higher-level social cognition: Eye gaze perception as a bridge in a transdiagnostic sample enriched with social dysfunction.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: The link between basic visual processing and higher-level social cognition: Eye gaze perception as a bridge in a transdiagnostic sample enriched with social dysfunction.
Συγγραφείς: Mathis K; Department of Psychiatry and Behavioral Health, https://ror.org/00rs6vg23The Ohio State University, Columbus, OH, United States., Blain SD; Department of Psychiatry and Behavioral Health, https://ror.org/00rs6vg23The Ohio State University, Columbus, OH, United States., Locarno L; Department of Psychiatry and Behavioral Health, https://ror.org/00rs6vg23The Ohio State University, Columbus, OH, United States., Lasagna CA; Department of Psychology, https://ror.org/00jmfr291University of Michigan, Ann Arbor, MI, United States., DeStefani S; Department of Psychiatry and Behavioral Health, https://ror.org/00rs6vg23The Ohio State University, Columbus, OH, United States., Kraft J; Department of Psychology, https://ror.org/0043h8f16University of South Dakota, Vermillion, SD, United States., Colombi C; https://ror.org/02w8ez808IRCCS Stella Maris Foundation, 56128 Pisa, Italy., Thakkar KN; Department of Psychology, https://ror.org/05hs6h993Michigan State University, East Lansing, MI, United States., Burton CZ; Department of Psychology, https://ror.org/00jmfr291University of Michigan, Ann Arbor, MI, United States.; Department of Psychiatry, https://ror.org/00jmfr291University of Michigan, Ann Arbor, MI, United States., Tso IF; Department of Psychiatry and Behavioral Health, https://ror.org/00rs6vg23The Ohio State University, Columbus, OH, United States.; Department of Psychology, https://ror.org/00jmfr291University of Michigan, Ann Arbor, MI, United States.; Department of Psychiatry, https://ror.org/00jmfr291University of Michigan, Ann Arbor, MI, United States.
Πηγή: Psychological medicine [Psychol Med] 2026 May 14; Vol. 56, pp. e152. Date of Electronic Publication: 2026 May 14.
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Cambridge University Press Country of Publication: England NLM ID: 1254142 Publication Model: Electronic Cited Medium: Internet ISSN: 1469-8978 (Electronic) Linking ISSN: 00332917 NLM ISO Abbreviation: Psychol Med Subsets: MEDLINE
Imprint Name(s): Publication: London : Cambridge University Press
Original Publication: London, British Medical Assn.
Ιατρικοί όροι (MeSH): Theory of Mind*/physiology , Visual Perception*/physiology , Fixation, Ocular*/physiology , Facial Recognition*/physiology , Social Cognition* , Social Perception*, Contrast Sensitivity/physiology ; Humans ; Female ; Male ; Adolescent ; Young Adult ; Emotions
Περίληψη: Background: Social cognitive deficits are common across many psychiatric conditions and contribute to broader social dysfunction. One hypothesized mechanism involves altered basic visual processing, which may disrupt the perception of low-level social cues and, in turn, compromise broader social cognitive processes. Here, we examined relations between basic visual processing and different levels of social cognition in a transdiagnostic youth sample.
Methods: A sample of 148 youth, ranging from healthy individuals to individuals with neuropsychiatric diagnoses and significant social dysfunction, completed two measures of basic visual processing (contrast sensitivity and visual integration) and a battery of social cognition tasks spanning lower-level (gaze perception) to mid-level (emotion recognition) to higher-level (theory of mind) social cognition. We used a four-level path model to test whether basic visual processing predicts gaze perception, which in turn predicts emotion recognition, which predicts theory of mind.
Results: Poorer contrast sensitivity and visual integration were associated with less precise gaze perception, which was, in turn, associated with worse emotion recognition, which was associated with worse theory of mind. This four-level path model demonstrated good fit and showed superior fit compared to alternative models.
Conclusions: These findings suggest that basic visual processing influences the perception of basic social cues (e.g. gaze direction), which subsequently impairs more complex social perception and inference. Notably, this study extends prior observations from individuals with chronic schizophrenia to a transdiagnostic youth sample, indicating that altered basic visual processing may be a shared mechanism contributing to social cognitive deficits across psychiatric disorders and illness stages.
Grant Information: R01 MH122491 United States MH NIMH NIH HHS; R01MH122491 United States MH NIMH NIH HHS; DGE-1841052 National Science Foundation Graduate Research Fellowship Program
Contributed Indexing: Keywords: contrast sensitivity; emotion recognition; gaze perception; social cognition; theory of mind; transdiagnostic; vision; visual integration
Entry Date(s): Date Created: 20260514 Date Completed: 20260717 Latest Revision: 20260717
Update Code: 20260717
PubMed Central ID: PMC13200143
DOI: 10.1017/S0033291726104589
PMID: 42132002
Βάση Δεδομένων: MEDLINE
FullText Links:
  – Type: other
    Url: https://resolver.ebsco.com:443/public/rma-ftfapi/ejs/direct?AccessToken=456CB7BE7BE2803BDB5E&Show=Object
Text:
  Availability: 0
Header DbId: cmedm
DbLabel: MEDLINE
An: 42132002
AccessLevel: 3
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: The link between basic visual processing and higher-level social cognition: Eye gaze perception as a bridge in a transdiagnostic sample enriched with social dysfunction.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Mathis+K%22">Mathis K</searchLink>; Department of Psychiatry and Behavioral Health, https://ror.org/00rs6vg23The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Blain+SD%22">Blain SD</searchLink>; Department of Psychiatry and Behavioral Health, https://ror.org/00rs6vg23The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Locarno+L%22">Locarno L</searchLink>; Department of Psychiatry and Behavioral Health, https://ror.org/00rs6vg23The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Lasagna+CA%22">Lasagna CA</searchLink>; Department of Psychology, https://ror.org/00jmfr291University of Michigan, Ann Arbor, MI, United States.<br /><searchLink fieldCode="AU" term="%22DeStefani+S%22">DeStefani S</searchLink>; Department of Psychiatry and Behavioral Health, https://ror.org/00rs6vg23The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Kraft+J%22">Kraft J</searchLink>; Department of Psychology, https://ror.org/0043h8f16University of South Dakota, Vermillion, SD, United States.<br /><searchLink fieldCode="AU" term="%22Colombi+C%22">Colombi C</searchLink>; https://ror.org/02w8ez808IRCCS Stella Maris Foundation, 56128 Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Thakkar+KN%22">Thakkar KN</searchLink>; Department of Psychology, https://ror.org/05hs6h993Michigan State University, East Lansing, MI, United States.<br /><searchLink fieldCode="AU" term="%22Burton+CZ%22">Burton CZ</searchLink>; Department of Psychology, https://ror.org/00jmfr291University of Michigan, Ann Arbor, MI, United States.; Department of Psychiatry, https://ror.org/00jmfr291University of Michigan, Ann Arbor, MI, United States.<br /><searchLink fieldCode="AU" term="%22Tso+IF%22">Tso IF</searchLink>; Department of Psychiatry and Behavioral Health, https://ror.org/00rs6vg23The Ohio State University, Columbus, OH, United States.; Department of Psychology, https://ror.org/00jmfr291University of Michigan, Ann Arbor, MI, United States.; Department of Psychiatry, https://ror.org/00jmfr291University of Michigan, Ann Arbor, MI, United States.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%221254142%22">Psychological medicine</searchLink> [Psychol Med] 2026 May 14; Vol. 56, pp. e152. <i>Date of Electronic Publication: </i>2026 May 14.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: Language
  Label: Language
  Group: Lang
  Data: English
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cambridge+University+Press%22">Cambridge University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>1254142 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1469-8978 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200332917%22">00332917 </searchLink><i>NLM ISO Abbreviation: </i>Psychol Med <i>Subsets: </i>MEDLINE
– Name: PublisherInfo
  Label: Imprint Name(s)
  Group: PubInfo
  Data: <i>Publication</i>: London : Cambridge University Press<br /><i>Original Publication</i>: London, British Medical Assn.
– Name: SubjectMESH
  Label: MeSH Terms
  Group: Su
  Data: <searchLink fieldCode="MM" term="%22Theory+of+Mind%22">Theory of Mind*</searchLink>/<searchLink fieldCode="MM" term="%22Theory+of+Mind+physiology%22">physiology</searchLink> <br /><searchLink fieldCode="MM" term="%22Visual+Perception%22">Visual Perception*</searchLink>/<searchLink fieldCode="MM" term="%22Visual+Perception+physiology%22">physiology</searchLink> <br /><searchLink fieldCode="MM" term="%22Fixation%2C+Ocular%22">Fixation, Ocular*</searchLink>/<searchLink fieldCode="MM" term="%22Fixation%2C+Ocular+physiology%22">physiology</searchLink> <br /><searchLink fieldCode="MM" term="%22Facial+Recognition%22">Facial Recognition*</searchLink>/<searchLink fieldCode="MM" term="%22Facial+Recognition+physiology%22">physiology</searchLink> <br /><searchLink fieldCode="MM" term="%22Social+Cognition%22">Social Cognition*</searchLink> <br /><searchLink fieldCode="MM" term="%22Social+Perception%22">Social Perception*</searchLink><br /><searchLink fieldCode="MH" term="%22Contrast+Sensitivity%22">Contrast Sensitivity</searchLink>/<searchLink fieldCode="MH" term="%22Contrast+Sensitivity+physiology%22">physiology</searchLink> ; <searchLink fieldCode="MH" term="%22Humans%22">Humans</searchLink> ; <searchLink fieldCode="MH" term="%22Female%22">Female</searchLink> ; <searchLink fieldCode="MH" term="%22Male%22">Male</searchLink> ; <searchLink fieldCode="MH" term="%22Adolescent%22">Adolescent</searchLink> ; <searchLink fieldCode="MH" term="%22Young+Adult%22">Young Adult</searchLink> ; <searchLink fieldCode="MH" term="%22Emotions%22">Emotions</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Social cognitive deficits are common across many psychiatric conditions and contribute to broader social dysfunction. One hypothesized mechanism involves altered basic visual processing, which may disrupt the perception of low-level social cues and, in turn, compromise broader social cognitive processes. Here, we examined relations between basic visual processing and different levels of social cognition in a transdiagnostic youth sample.<br />Methods: A sample of 148 youth, ranging from healthy individuals to individuals with neuropsychiatric diagnoses and significant social dysfunction, completed two measures of basic visual processing (contrast sensitivity and visual integration) and a battery of social cognition tasks spanning lower-level (gaze perception) to mid-level (emotion recognition) to higher-level (theory of mind) social cognition. We used a four-level path model to test whether basic visual processing predicts gaze perception, which in turn predicts emotion recognition, which predicts theory of mind.<br />Results: Poorer contrast sensitivity and visual integration were associated with less precise gaze perception, which was, in turn, associated with worse emotion recognition, which was associated with worse theory of mind. This four-level path model demonstrated good fit and showed superior fit compared to alternative models.<br />Conclusions: These findings suggest that basic visual processing influences the perception of basic social cues (e.g. gaze direction), which subsequently impairs more complex social perception and inference. Notably, this study extends prior observations from individuals with chronic schizophrenia to a transdiagnostic youth sample, indicating that altered basic visual processing may be a shared mechanism contributing to social cognitive deficits across psychiatric disorders and illness stages.
– Name: GrantInfo
  Label: Grant Information
  Group: Grant
  Data: R01 MH122491 United States MH NIMH NIH HHS; R01MH122491 United States MH NIMH NIH HHS; DGE-1841052 National Science Foundation Graduate Research Fellowship Program
– Name: SubjectMinor
  Label: Contributed Indexing
  Group:
  Data: <i>Keywords: </i>contrast sensitivity; emotion recognition; gaze perception; social cognition; theory of mind; transdiagnostic; vision; visual integration
– Name: DateEntry
  Label: Entry Date(s)
  Group: Date
  Data: <i>Date Created: </i>20260514 <i>Date Completed: </i>20260717 <i>Latest Revision: </i>20260717
– Name: DateUpdate
  Label: Update Code
  Group: Date
  Data: 20260717
– Name: PubmedCentralID
  Label: PubMed Central ID
  Group: ID
  Data: PMC13200143
– Name: DOI
  Label: DOI
  Group: ID
  Data: 10.1017/S0033291726104589
– Name: AN
  Label: PMID
  Group: ID
  Data: 42132002
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=cmedm&AN=42132002
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1017/S0033291726104589
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: e152
    Subjects:
      – SubjectFull: Contrast Sensitivity physiology
        Type: general
      – SubjectFull: Humans
        Type: general
      – SubjectFull: Female
        Type: general
      – SubjectFull: Male
        Type: general
      – SubjectFull: Adolescent
        Type: general
      – SubjectFull: Young Adult
        Type: general
      – SubjectFull: Emotions
        Type: general
      – SubjectFull: Theory of Mind physiology
        Type: general
      – SubjectFull: Visual Perception physiology
        Type: general
      – SubjectFull: Fixation, Ocular physiology
        Type: general
      – SubjectFull: Facial Recognition physiology
        Type: general
      – SubjectFull: Social Cognition
        Type: general
      – SubjectFull: Social Perception
        Type: general
    Titles:
      – TitleFull: The link between basic visual processing and higher-level social cognition: Eye gaze perception as a bridge in a transdiagnostic sample enriched with social dysfunction.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Mathis K
      – PersonEntity:
          Name:
            NameFull: Blain SD
      – PersonEntity:
          Name:
            NameFull: Locarno L
      – PersonEntity:
          Name:
            NameFull: Lasagna CA
      – PersonEntity:
          Name:
            NameFull: DeStefani S
      – PersonEntity:
          Name:
            NameFull: Kraft J
      – PersonEntity:
          Name:
            NameFull: Colombi C
      – PersonEntity:
          Name:
            NameFull: Thakkar KN
      – PersonEntity:
          Name:
            NameFull: Burton CZ
      – PersonEntity:
          Name:
            NameFull: Tso IF
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 14
              M: 05
              Text: 2026 May 14
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1469-8978
          Numbering:
            – Type: volume
              Value: 56
          Titles:
            – TitleFull: Psychological medicine
              Type: main
ResultId 1