Academic Journal
Prevalence and determinants of human papillomavirus vaccine hesitancy among parents of young girls in Morocco.
| Τίτλος: | Prevalence and determinants of human papillomavirus vaccine hesitancy among parents of young girls in Morocco. |
|---|---|
| Συγγραφείς: | Essayagh T; Hassan First University of Settat, Institut supérieur des sciences de la santé, Laboratoire Sciences et Ingénierie Biomédicale, Biophysique et Santé, Settat, Morocco., Essayagh M; Office National de Sécurité Sanitaire des produits Alimentaires, Meknès, Morocco., Lemriss H; Hassan First University of Settat, Institut supérieur des sciences de la santé, Laboratoire Sciences et Ingénierie Biomédicale, Biophysique et Santé, Settat, Morocco., Mourad R; Hassan First University of Settat, Institut supérieur des sciences de la santé, Laboratoire Sciences et Ingénierie Biomédicale, Biophysique et Santé, Settat, Morocco., Nmila K; Hassan First University of Settat, Institut supérieur des sciences de la santé, Laboratoire Sciences et Ingénierie Biomédicale, Biophysique et Santé, Settat, Morocco., Slibani H; Hassan First University of Settat, Institut supérieur des sciences de la santé, Laboratoire Sciences et Ingénierie Biomédicale, Biophysique et Santé, Settat, Morocco., Hachimi SE; Hassan First University of Settat, Institut supérieur des sciences de la santé, Laboratoire Sciences et Ingénierie Biomédicale, Biophysique et Santé, Settat, Morocco., Boukhari ME; Hassan First University of Settat, Institut supérieur des sciences de la santé, Laboratoire Sciences et Ingénierie Biomédicale, Biophysique et Santé, Settat, Morocco., Addakiri K; Hassan First University of Settat, Institut supérieur des sciences de la santé, Laboratoire Sciences et Ingénierie Biomédicale, Biophysique et Santé, Settat, Morocco., Zadran R; National Infectious Diseases Hospital Laboratory, Kabul, Afghanistan. rt.zadran2025@gmail.com., Tigaidi H; Faculty of Public and Environmental Health, University of Kordofan, Elobeid, Sudan., Lemriss S; Laboratoire of Research and Medical Analysis of Gendarmerie Royale, Department of Biosafety PCL3, Rabat, 10100, Morocco., Essayagh S; Hassan First University of Settat, Faculté des Sciences et Techniques, Laboratoire Agroalimentaire et Santé, Settat, Morocco. |
| Πηγή: | Scientific reports [Sci Rep] 2026 May 11; Vol. 16 (1). Date of Electronic Publication: 2026 May 11. |
| Τύπος έκδοσης: | Journal Article; Multicenter Study |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: London : Nature Publishing Group, copyright 2011- |
| Ιατρικοί όροι (MeSH): | Papillomavirus Vaccines*/administration & dosage , Parents*/psychology , Papillomavirus Infections*/prevention & control , Papillomavirus Infections*/epidemiology , Papillomavirus Infections*/virology , Vaccination Hesitancy*/statistics & numerical data , Vaccination Hesitancy*/psychology , Uterine Cervical Neoplasms*/prevention & control , Uterine Cervical Neoplasms*/virology , Human Papillomavirus Viruses*/immunology, Morocco/epidemiology ; Vaccination/psychology ; Humans ; Female ; Adolescent ; Cross-Sectional Studies ; Prevalence ; Health Knowledge, Attitudes, Practice ; Adult ; Child ; Middle Aged ; Surveys and Questionnaires |
| Περίληψη: | The vaccination against Human papillomavirus (HPV) effectively prevents cervical cancer, nevertheless, parental hesitancy limits coverage and reduces the impact of prevention programs. This study sought to estimate the prevalence of parental hesitancy toward HPV vaccination in Morocco and to identify the factors associated with it. A multicenter cross-sectional survey was conducted between March and September 2025 among parents of girls aged 11-14 years attending healthcare centers in Morocco. Trained interviewers administered a structured questionnaire to collect data on socioeconomic characteristics, knowledge of cervical cancer and HPV vaccination, trust in the healthcare system, social influences, and perceptions of HPV infection. We then applied multivariate logistic regression to identify factors associated with vaccine hesitancy. Data were analyzed using Epi Info™ software, version 7.2.0.1. A total of 2,088 parents with an average age of 37.9 ± 6.3 years were surveyed. Among these parents, 1,771 stated that they were hesitant to have their daughters vaccinated, representing a prevalence of 84.8% (1,771/2,088). Factors significantly associated with hesitancy included lack trust in the healthcare system (Adjusted Odds Ratio (AOR) 17.23; 95% CI [4.31-68.8]; p-value = 0.0001), low trust in the healthcare system (AOR 1.91; 95% CI [1.21-3.02]; p = 0.004), absence of recommendation from healthcare professionals (AOR 6.8; CI [2.99-15.47]; p < 0.001), not having ever heard of cervical cancer (AOR 2.94; CI [1.71-5.07]; p = 0.0001), negative media influences (AOR 2.68; CI [1.53-4.68]; p = 0.0005), societal norms (AOR 2.68; CI [1.68-4.30]; p < 0.01), low perception of HPV severity (AOR 2.58; CI [1.22-5.43]; p = 0.01), concerns about adverse reactions (AOR 2.34; CI [1.39-3.94]; p = 0.01), walking to the health center (AOR 2.23; CI [1.54-3.23]; p < 0.001), rural residence (AOR 2.01; CI [1.37-2.95]; p = 0.0004), and limited knowledge of cervical cancer complications (AOR1.88; CI [1.15-3.07]; p = 0.01). Higher monthly income was protective against hesitancy (AOR 0.39; CI [0.25-0.62]; p = 0.0001). Parental hesitancy toward HPV vaccination in Morocco is shaped by social, knowledge, and access factors. Addressing these barriers requires a comprehensive approach, including education and awareness campaigns, bolstering healthcare trust, improving access to vaccination services, and community mobilization to promote vaccine adoption. (© 2026. The Author(s).) |
| Competing Interests: | Declarations. Competing interests: The authors declare no competing interests. |
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| Grant Information: | AP24-01559 TD/EMRO |
| Contributed Indexing: | Keywords: Barriers and implications; Girls; Hesitancy; Human papillomavirus; Prevalence; Vaccine |
| Substance Nomenclature: | 0 (Papillomavirus Vaccines) |
| Entry Date(s): | Date Created: 20260511 Date Completed: 20260708 Latest Revision: 20260813 |
| Update Code: | 20260813 |
| PubMed Central ID: | PMC13346954 |
| DOI: | 10.1038/s41598-026-52998-3 |
| PMID: | 42115278 |
| Βάση Δεδομένων: | MEDLINE |
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