Academic Journal
Executive dysfunction in military PTSD with ecological sleep assessment: A cross-sectional study.
| Τίτλος: | Executive dysfunction in military PTSD with ecological sleep assessment: A cross-sectional study. |
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| Συγγραφείς: | Sipahimalani G; Department of Psychiatry, Percy National Military Teaching Hospital, 2 Rue Lieutenant Raoul Batany 92140 Clamart, France. Electronic address: gilles.sipahi@hotmail.fr., Sauvet F; UMR 7330 VIFASOM (Vigilance, Fatigue, Sleep and Public Health), Université Paris Cité, 85 Boulevard Saint-Germain 75006 Paris, France; French Armed Forces Biomedical Research Institute (IRBA), 1 Place General Valerie Andre 91220 Bretigny-sur-Orge France; Val-de-Grâce French Military Medical Academy, 1 Place Alphonse Laveran 75005 Paris, France. Electronic address: fabien.sauvet@intradef.gouv.fr., Quiquempoix M; UMR 7330 VIFASOM (Vigilance, Fatigue, Sleep and Public Health), Université Paris Cité, 85 Boulevard Saint-Germain 75006 Paris, France; French Armed Forces Biomedical Research Institute (IRBA), 1 Place General Valerie Andre 91220 Bretigny-sur-Orge France., Feingold D; UMR 7330 VIFASOM (Vigilance, Fatigue, Sleep and Public Health), Université Paris Cité, 85 Boulevard Saint-Germain 75006 Paris, France., Jacques C; UMR 7330 VIFASOM (Vigilance, Fatigue, Sleep and Public Health), Université Paris Cité, 85 Boulevard Saint-Germain 75006 Paris, France., Guillard M; UMR 7330 VIFASOM (Vigilance, Fatigue, Sleep and Public Health), Université Paris Cité, 85 Boulevard Saint-Germain 75006 Paris, France; French Armed Forces Biomedical Research Institute (IRBA), 1 Place General Valerie Andre 91220 Bretigny-sur-Orge France., Lahutte B; Val-de-Grâce French Military Medical Academy, 1 Place Alphonse Laveran 75005 Paris, France; Department of Psychiatry, Begin National Military Teaching Hospital, 69 Avenue de Paris 94160 Saint-Mandé, France. Electronic address: bertrand.lahutte@intradef.gouv.fr., Chennaoui M; UMR 7330 VIFASOM (Vigilance, Fatigue, Sleep and Public Health), Université Paris Cité, 85 Boulevard Saint-Germain 75006 Paris, France; French Armed Forces Biomedical Research Institute (IRBA), 1 Place General Valerie Andre 91220 Bretigny-sur-Orge France. Electronic address: mounir1.chennaoui@intradef.gouv.fr., Saguin E; UMR 7330 VIFASOM (Vigilance, Fatigue, Sleep and Public Health), Université Paris Cité, 85 Boulevard Saint-Germain 75006 Paris, France; Val-de-Grâce French Military Medical Academy, 1 Place Alphonse Laveran 75005 Paris, France. Electronic address: emeric.saguin@intradef.gouv.fr. |
| Πηγή: | Psychiatry research [Psychiatry Res] 2026 Aug; Vol. 362, pp. 117211. Date of Electronic Publication: 2026 Apr 30. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Ireland NLM ID: 7911385 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7123 (Electronic) Linking ISSN: 01651781 NLM ISO Abbreviation: Psychiatry Res Subsets: MEDLINE |
| Imprint Name(s): | Publication: Limerick : Elsevier/North-Holland Biomedical Press Original Publication: Amsterdam, Elsevier/North-Holland Biomedical Press. |
| Ιατρικοί όροι (MeSH): | Stress Disorders, Post-Traumatic*/complications , Stress Disorders, Post-Traumatic*/psychology , Military Personnel*/psychology , Executive Function*/physiology , Cognition Disorders*/etiology , Sleep Wake Disorders*/etiology, Memory, Short-Term/physiology ; Humans ; Male ; Adult ; Cross-Sectional Studies ; Neuropsychological Tests ; Female ; Polysomnography ; Attention ; Psychiatric Status Rating Scales ; Inhibition, Psychological |
| Περίληψη: | Background: Post-Traumatic Stress Disorder (PTSD) is consistently linked to deficits in executive functions, including attention, working memory, and inhibitory control, which impact clinical outcomes. This study examined these cognitive functions in military personnel with PTSD and its associations with clinical symptoms and objective sleep parameters. Methods: French active-duty and veteran service members with PTSD (n = 130) and healthy military controls (n = 65) completed computerized cognitive tasks: inhibition (Go/No-Go), sustained attention (0-Back), and working memory (2-Back). Sleep was monitored under ecological conditions using a polysomnographic headband. Clinical assessments included PTSD severity (PCL-5) and depression (BDI). Efficiency scores combining accuracy and speed were calculated for each task. Group comparisons, correlations, and multiple regressions were conducted. Executive impairment thresholds were derived from the controls to estimate prevalence in the PTSD group. Results: PTSD participants showed lower performance across the three cognitive tasks. Using normative thresholds, 36.6% met criteria for executive impairment. In the PTSD group, clinical and sleep variables explained only a small proportion of the variance in cognitive performance (R² = 0.12), with REM sleep and PTSD severity showing the largest albeit modest contributions. In contrast, predictors explained a greater proportion of variance in controls (R² = 0.35), suggesting stronger predictive utility. Exploratory analyses indicated that medication burden was the strongest individual predictor of executive performance in PTSD. Conclusion: Executive dysfunction is frequent among military personnel with PTSD and only partially explained by standard clinical and sleep measures. Cognitive impairment likely reflects multiple interacting mechanisms not captured by standard assessments, underscoring the need for integrative and multimodal approaches. (Copyright © 2026 The Author(s). Published by Elsevier B.V. All rights reserved.) |
| Competing Interests: | Declaration of competing interest The authors report no conflict of interest. |
| Contributed Indexing: | Keywords: Cognitive impairment; Cognitive performance; Executive function; Military personnel; Post-traumatic stress disorder; Psychotropic drugs; Sleep disturbances |
| Entry Date(s): | Date Created: 20260508 Date Completed: 20260716 Latest Revision: 20260716 |
| Update Code: | 20260716 |
| DOI: | 10.1016/j.psychres.2026.117211 |
| PMID: | 42102530 |
| Βάση Δεδομένων: | MEDLINE |
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