Academic Journal
Changes of borderline symptoms, personality functioning, and dysfunctional personality traits after dialectical-behavioral therapy in borderline personality disorder.
| Τίτλος: | Changes of borderline symptoms, personality functioning, and dysfunctional personality traits after dialectical-behavioral therapy in borderline personality disorder. |
|---|---|
| Συγγραφείς: | Kunz JI; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336, Munich, Germany. Julia.Kunz@med.uni-muenchen.de.; DZPG (German Center for Mental Health), Partner Site Munich-Augsburg, Munich, Germany. Julia.Kunz@med.uni-muenchen.de., Zwick A; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336, Munich, Germany., Boll JJ; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336, Munich, Germany., Wolf J; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336, Munich, Germany.; DZPG (German Center for Mental Health), Partner Site Munich-Augsburg, Munich, Germany., Meinhardt J; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336, Munich, Germany., Hüttner S; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336, Munich, Germany., Grigo R; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336, Munich, Germany., Musil R; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336, Munich, Germany.; Oberberg Fachklinik Bad Tölz, Buchener Str. 17, 83646, Bad Tölz, Germany., Goerigk S; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336, Munich, Germany.; DZPG (German Center for Mental Health), Partner Site Munich-Augsburg, Munich, Germany.; Charlotte Fresenius Hochschule Munich, Infanteriestr. 11a, 80797, Munich, Germany., Jobst A; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336, Munich, Germany.; DZPG (German Center for Mental Health), Partner Site Munich-Augsburg, Munich, Germany., Padberg F; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336, Munich, Germany.; DZPG (German Center for Mental Health), Partner Site Munich-Augsburg, Munich, Germany., Reinhard MA; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336, Munich, Germany.; DZPG (German Center for Mental Health), Partner Site Munich-Augsburg, Munich, Germany. |
| Πηγή: | European archives of psychiatry and clinical neuroscience [Eur Arch Psychiatry Clin Neurosci] 2026 Aug; Vol. 276 (5), pp. 2159-2172. Date of Electronic Publication: 2026 May 08. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Springer International Country of Publication: Germany NLM ID: 9103030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1433-8491 (Electronic) Linking ISSN: 09401334 NLM ISO Abbreviation: Eur Arch Psychiatry Clin Neurosci Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Berlin ; New York : Springer International, c1990- |
| Ιατρικοί όροι (MeSH): | Borderline Personality Disorder*/therapy , Borderline Personality Disorder*/physiopathology , Borderline Personality Disorder*/rehabilitation , Borderline Personality Disorder*/psychology , Dialectical Behavior Therapy*/methods , Personality*/physiology, Humans ; Female ; Adult ; Male ; Psychiatric Status Rating Scales ; Young Adult ; Treatment Outcome |
| Περίληψη: | Borderline Personality Disorder (BPD) is a complex and debilitating condition characterized by limited treatment response and high dropout rates across treatments, even in leading therapeutic approaches, such as Dialectical-Behavioral Therapy (DBT). Given the heterogeneity of BPD symptomatology and the current shift toward dimensional assessments of personality disorders, this study investigates whether dimensional measures according to the DSM-5's Alternative Model for Personality Disorders (AMPD) may serve as additional markers of treatment outcome and dropout. Eighty-five participants with BPD were recruited from a naturalistic inpatient DBT program. Associations between BPD symptoms (Borderline Symptom List, Borderline Personality Disorder Severity Index), personality functioning (Level of Personality Functioning Scale - Brief Form 2.0), and dysfunctional personality traits (Personality Inventory for DSM-5 and ICD-11 - Brief Form Plus) were examined at baseline, as well as their sensitivity to change after DBT. At baseline, both personality functioning and dysfunctional personality traits, except antagonism, were associated with BPD symptoms (all r ≥ 0.4). After 10 weeks of DBT, parallel improvements were observed in personality functioning and dysfunctional personality traits, with significant reductions in negative affectivity and detachment. Elevated baseline levels of negative affectivity and psychoticism were associated with less BPD symptom change. DBT dropout was linked to higher impairment in negative affectivity and anankastia at admission. Personality functioning showed greater sensitivity to change throughout DBT compared to dysfunctional personality traits. These findings emphasize how AMPD may yield benefits beyond categorical BPD diagnoses, potentially contributing to more personalized and effective treatment planning and preventing dropouts. (© 2026. The Author(s).) |
| Competing Interests: | Declarations. Conflict of interest: FP is a member of the European Scientific Advisory Board of Brainsway Inc., Jerusalem, Israel, and the International Scientific Advisory Board of Sooma, Helsinki, Finland. He has received speaker’s honoraria from Mag&More GmbH and the neuroCare Group. His lab has received support with equipment from neuroConn GmbH, Ilmenau, Germany, and Mag&More GmbH and Brainsway Inc., Jerusalem, Israel. RM has received financial research support from the EU (H2020 No. 754740) and served as PI in clinical trials from Abide Therapeutics, Böhringer-Ingelheim, Emalex Biosciences, Lundbeck GmbH, Nuvelution TS Pharma Inc., Oryzon, Otsuka Pharmaceuticals and Therapix Biosciences. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Ethical Approval: This study was part of an ongoing naturalistic study of the Department of Psychiatry and Psychotherapy of the LMU University Hospital, LMU Munich, Germany (German Clinical Trial Register ID: DRKS00019821) which was approved by the local ethics committee of the Faculty of Medicine, LMU Munich (EK-No. 713 − 15). The study was designed in accordance with the Declaration of Helsinki of 1964 as well as its subsequent amendments. All methods followed the German Psychological Society’s ethical guidelines, a German adaptation of the “Ethical Principles of Psychologists and Code of Conduct” of the American Psychiatric Association. Consent to Participate: All participants gave written informed consent. Consent to Publish: All participants gave written informed consent regarding publishing. |
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| Contributed Indexing: | Keywords: Alternative model for personality disorders; Borderline personality disorder; Dialectical-behavioral therapy; Dysfunctional personality traits; Personality functioning |
| Entry Date(s): | Date Created: 20260508 Date Completed: 20260818 Latest Revision: 20260820 |
| Update Code: | 20260820 |
| PubMed Central ID: | PMC13481579 |
| DOI: | 10.1007/s00406-026-02215-z |
| PMID: | 42101495 |
| Βάση Δεδομένων: | MEDLINE |
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