Academic Journal
Dynamic and integrative visual processing abilities in schizophrenia.
| Τίτλος: | Dynamic and integrative visual processing abilities in schizophrenia. |
|---|---|
| Συγγραφείς: | Lan M; State Key Laboratory of Cognitive Science and Mental Health, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China; University of Chinese Academy of Sciences, 100049, Beijing, China., Wang L; State Key Laboratory of Cognitive Science and Mental Health, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China., Wang B; State Key Laboratory of Cognitive Science and Mental Health, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China; University of Chinese Academy of Sciences, 100049, Beijing, China; Institute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, China., Cao T; State Key Laboratory of Cognitive Science and Mental Health, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China., Wang Z; Beijing HuiLongguan Hospital, Peking University HuiLongGuan Clinical Medical School, Beijing, China., Wang K; Institute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, China; Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, China., He S; State Key Laboratory of Cognitive Science and Mental Health, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China; University of Chinese Academy of Sciences, 100049, Beijing, China; Institute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, China. Electronic address: hes@ibp.ac.cn. |
| Πηγή: | Schizophrenia research [Schizophr Res] 2026 Aug; Vol. 294, pp. 155-163. Date of Electronic Publication: 2026 May 05. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Elsevier Science Publisher B. V Country of Publication: Netherlands NLM ID: 8804207 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2509 (Electronic) Linking ISSN: 09209964 NLM ISO Abbreviation: Schizophr Res Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Amsterdam : Elsevier Science Publisher B. V., c1988- |
| Ιατρικοί όροι (MeSH): | Schizophrenia*/complications , Schizophrenia*/physiopathology , Perceptual Disorders*/etiology , Visual Perception*/physiology , Schizophrenic Psychology*, Motion Perception/physiology ; Humans ; Female ; Male ; Adult ; Photic Stimulation ; Middle Aged ; Neuropsychological Tests ; Young Adult ; Vision, Binocular |
| Περίληψη: | Background: Visual perceptual functions are frequently disrupted in patients with schizophrenia. The nature and degree of the visual abnormalities experienced by patients provide important information about altered cognitive mechanisms and may serve as potential endophenotypes for classification and diagnosis of schizophrenia. Methods: To characterize dynamic and integrative visual functions and distinguish patients with schizophrenia from healthy controls, we compared performance on six visual tasks between patients and healthy controls. The tasks included binocular rivalry (interocular dynamics), structure from motion (3D-surface dynamics), surround suppression of contrast (contextual modulation), contour integration (form integration), coherent motion (motion integration), and motion speed discrimination (motion sensitivity). The same set of tests was conducted in 61 early-stage outpatients and 69 chronic inpatients and controls, allowing us to see the effects of long-term treatment on patients' visual functions. Results: Compared with healthy controls, patients experienced slower switching in binocular rivalry but faster switching in structure from motion, along with impaired spatial form integration. Inpatients had reduced motion sensitivity, while outpatients had deficits in motion integration, two groups differed in susceptibility to surround contrast suppression. Multidimensional test data supported more accurate classification between patients and controls. Conclusions: Patients with schizophrenia have specific patterns of visual perceptual abnormalities in dynamic and integrative information processing, with deficit in coherent motion (considered more state-linked) more apparent in early-stage outpatients and poor motion speed discrimination (linked to stable traits) seen in chronic inpatients. There is a significant advantage of using multiple independent tests to assist in the classification and diagnosis of schizophrenia. (Copyright © 2026 Elsevier B.V. All rights reserved.) |
| Competing Interests: | Declaration of competing interest The authors declare that they have no conflict of interest. |
| Contributed Indexing: | Keywords: Binocular rivalry; Contour integration; Motion perception; Multidimensional testing; Schizophrenia |
| Entry Date(s): | Date Created: 20260507 Date Completed: 20260611 Latest Revision: 20260611 |
| Update Code: | 20260611 |
| DOI: | 10.1016/j.schres.2026.04.029 |
| PMID: | 42092306 |
| Βάση Δεδομένων: | MEDLINE |
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