Mechanistic insights into Cd resilience enhancement by molybdenum trioxide nanoparticles in Solanum nigrum L.: Distinct molecular regulation from Mo6+ through multi-omics perspective.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Mechanistic insights into Cd resilience enhancement by molybdenum trioxide nanoparticles in Solanum nigrum L.: Distinct molecular regulation from Mo6+ through multi-omics perspective.
Συγγραφείς: Qin M; College of Environmental Science and Engineering and Key Laboratory of Environmental Biology and Pollution Control, Hunan University, Changsha 410082, China; Greater Bay Area Institute for Innovation, Hunan University, Guangzhou 511300, China; Shenzhen Institute, Hunan University, Shenzhen 518000, China., Gong J; College of Environmental Science and Engineering and Key Laboratory of Environmental Biology and Pollution Control, Hunan University, Changsha 410082, China; Greater Bay Area Institute for Innovation, Hunan University, Guangzhou 511300, China; Shenzhen Institute, Hunan University, Shenzhen 518000, China. Electronic address: jilaigong@gmail.com., Zeng G; College of Environmental Science and Engineering and Key Laboratory of Environmental Biology and Pollution Control, Hunan University, Changsha 410082, China. Electronic address: zgming@hnu.edu.cn., Song B; College of Environmental Science and Engineering and Key Laboratory of Environmental Biology and Pollution Control, Hunan University, Changsha 410082, China; Greater Bay Area Institute for Innovation, Hunan University, Guangzhou 511300, China; Shenzhen Institute, Hunan University, Shenzhen 518000, China., Cao W; School of Geographical Sciences, Hunan Normal University, Changsha 410081, China., Li H; College of Environmental Science and Engineering and Key Laboratory of Environmental Biology and Pollution Control, Hunan University, Changsha 410082, China; Greater Bay Area Institute for Innovation, Hunan University, Guangzhou 511300, China; Shenzhen Institute, Hunan University, Shenzhen 518000, China., Xu F; College of Environmental Science and Engineering and Key Laboratory of Environmental Biology and Pollution Control, Hunan University, Changsha 410082, China.
Πηγή: Journal of environmental sciences (China) [J Environ Sci (China)] 2026 Jun; Vol. 164, pp. 620-631. Date of Electronic Publication: 2025 Sep 27.
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: IOS Press Country of Publication: Netherlands NLM ID: 100967627 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1001-0742 (Print) Linking ISSN: 10010742 NLM ISO Abbreviation: J Environ Sci (China) Subsets: MEDLINE
Imprint Name(s): Publication: Amsterdam : IOS Press
Original Publication: Beijing : Editorial Dept. of Journal of Environmental Sciences (China), 1989-
Ιατρικοί όροι (MeSH): Molybdenum*/chemistry , Cadmium*/toxicity , Cadmium*/metabolism , Oxides*/chemistry , Solanum nigrum*/physiology , Solanum nigrum*/drug effects , Soil Pollutants*/toxicity , Soil Pollutants*/metabolism , Metal Nanoparticles*/chemistry, Nanoparticles/chemistry ; Biodegradation, Environmental ; Multiomics
Περίληψη: Recent studies have emphasized the promising application of nanotechnology to facilitate traditional phytoremediation of heavy metal pollution, while the systemic coordination between nano-enabled strategy and plant intrinsic regulatory pathways remains insufficiently characterized. This study comparatively analyzed the regulation of nano-scale molybdenum trioxide (MoO3 NPs) and ionic Mo (Mo6+) in enhancing both Cd tolerance and phytoextraction ability of Solanum nigrum L. through synchronized physiological profiling and multi-dimensional omics characterization. Experimental results indicated that both Mo materials enhanced leaf chlorophyll biosynthesis, nutrient assimilation, and antioxidative systems, meanwhile reallocating Cd distribution patterns to elevate resilience under Cd stress. A multi-omics analysis combined with transcriptomic and metabolomic analysis uncovered a root-mediated regulatory divergence between the two material types. Specifically, Mo6+ preferentially activated root primary metabolite biosynthesis and nutrient assimilation to counteract adverse influences on plant performances, while MoO3 NPs amplified stronger root expressions of intrinsic defense-related pathways, including antioxidative system, secondary metabolisms, phytohormone regulations, and heavy metal-tolerant protein, leading to more significant alleviation in the Cd-induced metabolic perturbations. These findings indicated the crosstalk between genetic regulations and biochemical responses of MoO3 NPs-exerted enhancement in Cd resistance of hyperaccumulator S. nigrum, providing mechanistic insights of nanomaterial-plant interaction for enhancing hyperaccumulator resilience during practical phytoremediation.
(Copyright © 2026. Published by Elsevier B.V.)
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Contributed Indexing: Keywords: Cadmium; Hyperaccumulator; Metabolomic; Molybdenum trioxide nanoparticles; Transcriptomic
Substance Nomenclature: 81AH48963U (Molybdenum)
00BH33GNGH (Cadmium)
0 (Oxides)
22FQ3F03YS (molybdenum trioxide)
0 (Soil Pollutants)
Entry Date(s): Date Created: 20260503 Date Completed: 20260716 Latest Revision: 20260716
Update Code: 20260716
DOI: 10.1016/j.jes.2025.09.051
PMID: 42070854
Βάση Δεδομένων: MEDLINE