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The effects of interaural time and level differences on the binaural interaction component of the auditory brainstem response in Cope's gray treefrogs.

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Title: The effects of interaural time and level differences on the binaural interaction component of the auditory brainstem response in Cope's gray treefrogs.
Authors: Pushpalatha Krishnan J; Department of Biology, Oklahoma State University, Stillwater, OK, USA., Chawla A; Department of Biology, Oklahoma State University, Stillwater, OK, USA., McCullagh EA; Department of Biology, Oklahoma State University, Stillwater, OK, USA., Reichert MS; Department of Biology, Oklahoma State University, Stillwater, OK, USA. michael.reichert@okstate.edu.
Source: Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology [J Comp Physiol A Neuroethol Sens Neural Behav Physiol] 2026 Sep; Vol. 212 (5), pp. 869-885. Date of Electronic Publication: 2026 May 03.
Publication Type: Journal Article
Language: English
Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 101141792 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1351 (Electronic) Linking ISSN: 03407594 NLM ISO Abbreviation: J Comp Physiol A Neuroethol Sens Neural Behav Physiol Subsets: MEDLINE
Imprint Name(s): Original Publication: Berlin ; New York : Springer, c2001-
MeSH Terms: Evoked Potentials, Auditory, Brain Stem*/physiology , Anura*/physiology , Sound Localization*/physiology , Brain Stem*/physiology , Auditory Perception*/physiology, Reaction Time/physiology ; Animals ; Female ; Male ; Acoustic Stimulation ; Time Factors
Abstract: Processing binaural cues is crucial for many acoustic communication tasks, and understanding the neural mechanisms of binaural sound processing gives important insights into how receivers localize signalers, which in anurans is a key component of mate selection. We characterized the binaural interaction component (BIC) of the auditory brainstem response (ABR) by collecting monaural and binaural ABRs using click stimuli with varying interaural time difference (ITD) and interaural level difference (ILD) in male and female Cope's gray treefrogs (Hyla chrysoscelis). We hypothesized that the latency of the BIC peaks would increase with larger ITDs and ILDs. We also hypothesized that females would show a stronger relationship between binaural cues and BIC characteristics than males because of the greater importance of directional hearing for females. We characterized two prominent BIC peaks, DN1 and DN2. Both BIC peak latencies had a positive relationship with ITD, but there was no effect of ITD on peak amplitudes. The amplitude and latency of the BIC peaks were not affected by variation in ILD. There were no sex or body size effects on ABR or BIC characteristics. Our findings demonstrate that the BIC is driven primarily by ITD in H. chrysoscelis. This is the first study to characterize the BIC in an amphibian, which expands the comparative understanding of the neural mechanisms of binaural hearing in vertebrates.
(© 2026. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Competing Interests: Declarations. Conflict of interest: The authors declare no competing interests.
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Contributed Indexing: Keywords: Auditory brainstem response; Binaural interaction component; Directional hearing; Interaural level difference; Interaural time difference; Sexual selection
Entry Date(s): Date Created: 20260503 Date Completed: 20261006 Latest Revision: 20261010
Update Code: 20261010
DOI: 10.1007/s00359-026-01811-7
PMID: 42070176
Database: MEDLINE
Description
ISSN:1432-1351
DOI:10.1007/s00359-026-01811-7