Academic Journal
Screening of microalgal strains with elevated α-tocopherol levels and antioxidant capacity for biotechnological applications.
| Τίτλος: | Screening of microalgal strains with elevated α-tocopherol levels and antioxidant capacity for biotechnological applications. |
|---|---|
| Συγγραφείς: | Maltseva I; Melitopol State University, Melitopol, Russia, 272312., Yakoviichuk A; Melitopol State University, Melitopol, Russia, 272312.; К.A. Timiryazev Institute of Plant Physiology RAS, IPP RAS, Moscow, 127276, Russia., Maltseva S; К.A. Timiryazev Institute of Plant Physiology RAS, IPP RAS, Moscow, 127276, Russia., Cherkashina S; Melitopol State University, Melitopol, Russia, 272312., Kulikovskiy M; К.A. Timiryazev Institute of Plant Physiology RAS, IPP RAS, Moscow, 127276, Russia., Maltsev Y; К.A. Timiryazev Institute of Plant Physiology RAS, IPP RAS, Moscow, 127276, Russia. ye.maltsev@gmail.com. |
| Πηγή: | Archives of microbiology [Arch Microbiol] 2026 Apr 24; Vol. 208 (7). Date of Electronic Publication: 2026 Apr 24. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0410427 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-072X (Electronic) Linking ISSN: 03028933 NLM ISO Abbreviation: Arch Microbiol Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Berlin, New York, Springer-Verlag. |
| Ιατρικοί όροι (MeSH): | alpha-Tocopherol*/metabolism , alpha-Tocopherol*/analysis , Microalgae*/metabolism , Microalgae*/chemistry , Microalgae*/classification , Microalgae*/growth & development , Microalgae*/genetics , Antioxidants*/metabolism , Antioxidants*/analysis, Chlorophyta/metabolism ; Chlorophyta/chemistry ; Chlorophyta/growth & development ; Biotechnology ; Phylogeny ; Biomass |
| Περίληψη: | One of the world's most important scientific challenges is addressing the global food crisis. Products offering potential health benefits, including various supplements with protective properties, have become a priority. Vitamin E is among the compounds gaining increasing attention from consumers. It is a group of compounds, with α-tocopherol of natural origin being the most bioavailable and valuable. This study investigated variations in α-tocopherol content, productivity, and antioxidant status at different growth stages in 15 microalgae strains from the Chlorophyta and Heterokontophyta. Results showed considerable diversity in α-tocopherol content, ranging from 8.0 to 773.8 µg g-1 dry weight, with a maximum for the Heterochlamydomonas strain at the late stationary phase. Significant intra‑species variability was observed, underscoring the importance of strain selection for biotechnological applications. Principal component analysis revealed distinct clustering patterns, distinguishing strains with high α-tocopherol content and antioxidant enzyme activity from those with lower levels. This underscored the intricate interplay between phylogeny, growth conditions, and antioxidant defences in microalgae. The obtained results provided opportunities for screening microalgae to obtain biomass with a high content of natural α-tocopherol, and opened new avenues for their utilisation in food supplements, cosmetics, and pharmaceuticals. (© 2026. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.) |
| Competing Interests: | Declarations. Conflict of interest: The authors declare no competing interests. Consent to participate: Not applicable. Consent for publication: Not applicable. |
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| Grant Information: | 25-14-00125 Russian Science Foundation; 124040100028-6 Ministry of Science and Higher Education of the Russian Federation; 124052200012-7 Ministry of Science and Higher Education of the Russian Federation |
| Contributed Indexing: | Keywords: Bracteacoccus; Coccomyxa; Heterochlamydomonas; Parietochloris; Vischeria; Algal collection; Enzymes; Thiobarbituric acid reactive substances; Vitamin E |
| Substance Nomenclature: | H4N855PNZ1 (alpha-Tocopherol) 0 (Antioxidants) |
| Entry Date(s): | Date Created: 20260424 Date Completed: 20260715 Latest Revision: 20260715 |
| Update Code: | 20260716 |
| DOI: | 10.1007/s00203-026-04923-5 |
| PMID: | 42030024 |
| Βάση Δεδομένων: | MEDLINE |
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