Academic Journal
Phenylpropanoid- and Flavonoid-Centered Metabolic Adaptation to Continuous Cropping Stress in Ornamental Gourd.
| Τίτλος: | Phenylpropanoid- and Flavonoid-Centered Metabolic Adaptation to Continuous Cropping Stress in Ornamental Gourd. |
|---|---|
| Συγγραφείς: | Li HY; Liaocheng Academy of Agricultural Sciences, Liaocheng 252000, China., Guo YP; Liaocheng Academy of Agricultural Sciences, Liaocheng 252000, China., Xie ZG; Liaocheng Academy of Agricultural Sciences, Liaocheng 252000, China., Xuan HQ; Liaocheng Academy of Agricultural Sciences, Liaocheng 252000, China., Wang SM; College of Food and Bio-Engineering, Beijing Vocational College of Agriculture, Beijing 102442, China., Wang XJ; Liaocheng Academy of Agricultural Sciences, Liaocheng 252000, China., Li WW; Liaocheng Academy of Agricultural Sciences, Liaocheng 252000, China., Lin GC; Liaocheng Academy of Agricultural Sciences, Liaocheng 252000, China., Hou X; College of Plant Protection, Shandong Agricultural University, Tai'an 271000, China. |
| Πηγή: | Metabolites [Metabolites] 2026 Mar 03; Vol. 16 (3). Date of Electronic Publication: 2026 Mar 03. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101578790 Publication Model: Electronic Cited Medium: Print ISSN: 2218-1989 (Print) Linking ISSN: 22181989 NLM ISO Abbreviation: Metabolites Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Original Publication: Basel : MDPI |
| Περίληψη: | Background: Continuous cropping severely restricts ornamental gourd productivity through yield decline, microbial dysbiosis, and rhizosphere autotoxin production. This study characterized rhizosphere-root-leaf metabolic reorganization under three-year monoculture, identifying key metabolites, pathways, and a hierarchical cascade for stress adaptation. Methods: Ornamental gourd seedlings were potted in three-year monoculture soil exhibiting replanting disorders. At the seven-leaf stage, rhizosphere soil, roots, and leaves were sampled for untargeted UHPLC-MS/MS metabolomics, followed by PCA, OPLS-DA, differential analysis (VIP > 1, p < 0.05), and KEGG pathway enrichment analysis. Results: A total of 10,792 metabolic features were detected in positive mode and 8992 in negative mode. PCA explained 83.84% of the variance, with PC1 at 56.35% and PC2 at 27.49%, clearly separating the compartments of the study. A total of 1132 shared metabolites were suppressed, with log2 fold changes exceeding -1. Roots displayed activation, with upregulated metabolites outnumbering downregulated ones, and log2 fold changes frequently exceeding +3. Leaves exhibited mean log2 fold changes of approximately +1 for phenylpropanoid intermediates, indole, and terpenoid biosynthesis. The enriched pathways included amino acid metabolism, phenylpropanoid and flavonoid biosynthesis, lipid metabolism, and hormone signaling. Conclusions: Continuous cropping induces a hierarchical rhizosphere-root-leaf metabolic cascade, linking suppressed soil activity with reinforced root defense and coordinated leaf signaling, centered on the phenylpropanoid and flavonoid pathways as key drivers of adaptation. |
| References: | BMC Genom Data. 2025 Sep 29;26(1):71. (PMID: 41023632) Plants (Basel). 2024 Nov 09;13(22):. (PMID: 39599358) Food Chem X. 2024 Feb 01;21:101159. (PMID: 38328697) Genes (Basel). 2024 Dec 27;16(1):. (PMID: 39858577) Plants (Basel). 2021 Apr 10;10(4):. (PMID: 33920170) Molecules. 2020 Nov 11;25(22):. (PMID: 33187049) Front Microbiol. 2025 Jul 30;16:1466452. (PMID: 40809056) Front Plant Sci. 2023 Jul 11;14:1192371. (PMID: 37496863) Plant Direct. 2025 Jun 01;9(6):e70074. (PMID: 40458253) Appl Biochem Biotechnol. 2025 May;197(5):3521-3547. (PMID: 39960613) F1000Res. 2020 Feb 26;9:. (PMID: 32148778) BMC Genomics. 2023 Feb 7;24(1):65. (PMID: 36750773) Front Plant Sci. 2025 Jun 26;16:1571825. (PMID: 40641862) Ecotoxicol Environ Saf. 2025 Mar 01;292:118005. (PMID: 40043503) Am J Transl Res. 2023 Aug 15;15(8):5216-5227. (PMID: 37692958) Front Plant Sci. 2022 May 09;13:881032. (PMID: 35615133) Int J Mol Sci. 2023 Aug 05;24(15):. (PMID: 37569843) Front Plant Sci. 2025 Jun 24;16:1603547. (PMID: 40630734) Biology (Basel). 2022 Jul 19;11(7):. (PMID: 36101454) J Agric Food Chem. 2025 Jan 29;73(4):2678-2695. (PMID: 39834325) Plant J. 2024 May;118(3):626-644. (PMID: 38241088) Foods. 2025 Mar 19;14(6):. (PMID: 40232096) Genomics. 2023 Sep;115(5):110675. (PMID: 37390936) Sci Rep. 2024 Dec 2;14(1):29999. (PMID: 39622925) Curr Res Food Sci. 2024 Nov 29;10:100938. (PMID: 39717680) Planta. 2024 Aug 20;260(4):77. (PMID: 39164400) Sci Rep. 2024 Aug 27;14(1):19865. (PMID: 39191882) Int J Mol Sci. 2025 Apr 25;26(9):. (PMID: 40362312) Chemosphere. 2021 May;270:128634. (PMID: 33082004) Plant Physiol Biochem. 2024 Oct;215:109064. (PMID: 39191042) Front Plant Sci. 2025 Apr 28;16:1489918. (PMID: 40357149) Plant Physiol Biochem. 2026 Feb;231:111011. (PMID: 41539149) BMC Plant Biol. 2024 Oct 12;24(1):954. (PMID: 39394556) Plants (Basel). 2023 Apr 14;12(8):. (PMID: 37111873) Int J Biol Macromol. 2024 Nov;279(Pt 1):135103. (PMID: 39197628) Plant J. 2017 Feb;89(4):825-838. (PMID: 27859865) Molecules. 2022 Nov 30;27(23):. (PMID: 36500459) Int J Mol Sci. 2024 Jul 29;25(15):. (PMID: 39125858) Genes (Basel). 2023 Dec 13;14(12):. (PMID: 38137030) Int J Mol Sci. 2013 Mar 01;14(3):4885-911. (PMID: 23455464) |
| Grant Information: | SDARS-05 Shandong Agriculture Research System; 2025YD87 Liaocheng Bureau of Science and Technology |
| Contributed Indexing: | Keywords: continuous cropping; flavonoid metabolism; metabolic reprogramming; phenylpropanoid; tissue-specific differentiation; untargeted metabolomics |
| Entry Date(s): | Date Created: 20260327 Date Completed: 20260327 Latest Revision: 20260813 |
| Update Code: | 20260813 |
| PubMed Central ID: | PMC13027611 |
| DOI: | 10.3390/metabo16030168 |
| PMID: | 41893319 |
| Βάση Δεδομένων: | MEDLINE |
καταχωρήστε σχόλιο πρώτοι!