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Continuous Beat-to-Beat Cuffless Blood Pressure Monitoring Using Wearable Radial Artery Tonometry.

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Τίτλος: Continuous Beat-to-Beat Cuffless Blood Pressure Monitoring Using Wearable Radial Artery Tonometry.
Συγγραφείς: Almadi M, Zhu G, Zheng Y, Li Q, Yang Y, Gong JS, Strangman G, Xiang T, Liu Z, Zhang Y, Clifford GD, Zhang Q
Πηγή: IEEE transactions on bio-medical engineering [IEEE Trans Biomed Eng] 2026 Mar 25; Vol. PP. Date of Electronic Publication: 2026 Mar 25.
Publication Model: Ahead of Print
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Institute Of Electrical And Electronics Engineers Country of Publication: United States NLM ID: 0012737 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-2531 (Electronic) Linking ISSN: 00189294 NLM ISO Abbreviation: IEEE Trans Biomed Eng Subsets: MEDLINE
Imprint Name(s): Publication: New York, NY : Institute Of Electrical And Electronics Engineers
Original Publication: New York, IEEE Professional Technical Group on Bio-Medical Engineering.
Περίληψη: Objective: To evaluate the feasibility of continuous beat-to-beat blood pressure (BP) monitoring using radial artery tonometry under controlled dynamic conditions in healthy adults.
Methods: Twenty healthy adults participated in laboratory recordings that included seated rest and controlled dynamic challenges, including isometric handgrip, cold pressor testing, and inspiratory threshold loading. Beat-to-beat BP was estimated from the tonometry waveform, with periodic cuff-anchored drift correction and automated signal quality indices applied to exclude corrupted segments. Tonometric BP measurements were compared against a Finapres continuous noninvasive reference device.
Results: Fourteen recordings met the stability criterion (94.2 $\pm$ 6.3% data retention, approximately 42,000 accepted beats). Agreement with the reference was strong, with Pearson correlation coefficients of 0.933, 0.945, and 0.954 for systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP), respectively. Corresponding mean absolute differences were 7.1 $\pm$ 5.7, 2.5 $\pm$ 2.5, and 3.8 $\pm$ 3.0 mmHg.
Conclusion: Radial artery tonometry with periodic drift correction and signal quality filtering demonstrated reliable beat-to-beat BP tracking during extended recordings that included controlled dynamic BP changes.
Significance: These findings support the feasibility of wearable radial artery tonometry for continuous cuffless BP monitoring and provide a reproducible basis for evaluating long-duration tonometric recordings under physiological stress conditions.
Grant Information: R01 EB027122 United States EB NIBIB NIH HHS
Entry Date(s): Date Created: 20260325 Latest Revision: 20260929
Update Code: 20260930
PubMed Central ID: PMC13268102
DOI: 10.1109/TBME.2026.3677590
PMID: 41880252
Βάση Δεδομένων: MEDLINE
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  Data: Continuous Beat-to-Beat Cuffless Blood Pressure Monitoring Using Wearable Radial Artery Tonometry.
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  Data: Objective: To evaluate the feasibility of continuous beat-to-beat blood pressure (BP) monitoring using radial artery tonometry under controlled dynamic conditions in healthy adults.<br />Methods: Twenty healthy adults participated in laboratory recordings that included seated rest and controlled dynamic challenges, including isometric handgrip, cold pressor testing, and inspiratory threshold loading. Beat-to-beat BP was estimated from the tonometry waveform, with periodic cuff-anchored drift correction and automated signal quality indices applied to exclude corrupted segments. Tonometric BP measurements were compared against a Finapres continuous noninvasive reference device.<br />Results: Fourteen recordings met the stability criterion (94.2 $\pm$ 6.3% data retention, approximately 42,000 accepted beats). Agreement with the reference was strong, with Pearson correlation coefficients of 0.933, 0.945, and 0.954 for systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP), respectively. Corresponding mean absolute differences were 7.1 $\pm$ 5.7, 2.5 $\pm$ 2.5, and 3.8 $\pm$ 3.0 mmHg.<br />Conclusion: Radial artery tonometry with periodic drift correction and signal quality filtering demonstrated reliable beat-to-beat BP tracking during extended recordings that included controlled dynamic BP changes.<br />Significance: These findings support the feasibility of wearable radial artery tonometry for continuous cuffless BP monitoring and provide a reproducible basis for evaluating long-duration tonometric recordings under physiological stress conditions.
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